Navigation Links
EPO Effective For Cancer Patients Suffering From Anemia

According to the third phase of clinical trail conducted by researchers at St. Jude Children's Research Hospital it was found that a weekly dose of erythropoietin //(EPO) is a very effective treatment for children suffering from cancer who develop anemia during chemotherapy.

EPO is a natural hormone that stimulates production of hemoglobin. It reduces the need for red blood cell (RBC) transfusions in these children. This is the first large-scale study of anemic children with cancer that randomly assigned patients to receive either EPO or a placebo (inactive ‘drug’) intravenously, and the first to measure the effect of EPO on quality of life in children, according to Bassem Razzouk, M.D., an associate member of the Department of Oncology at St. Jude.

Razzouk is the lead author of a report on this study that appears in the August 1 issue of the Journal of Clinical Oncology. ‘EPO was already known to benefit adults with cancer by increasing their hemoglobin level and improving their quality of life,’ Razzouk said. ‘But even though many children with cancer are anemic, there has been little evidence to support the use of EPO in such children who are receiving chemotherapy.’

Chemotherapy can suppress the production of red blood cells and cause anemia. ‘Our study showed that EPO not only improves the child's condition, but is also well tolerated, which makes it more acceptable to the patient,’ he added. The study was also significant because a smaller clinical trial at another institution included three subcutaneous injections per week of EPO, while children in the current study received EPO only once a week intravenously. ‘Our use of intravenous administration of EPO instead of subcutaneous injections reduced the suffering of children and allowed us to complete a major clinical trial that demonstrated the effectiveness of this treatment,’ Razzouk said.

The study, which was led by St. Jude, was conducted at 26 sites in the United States and included anemic patients 5 to 18 years of age who were receiving chemotherapy for solid tumors (excluding brain tumors), lymphoma and leukemia. A total of 111 patients received EPO and 111 received a placebo. The researchers studied the effect of EPO treatment on quality of life using a test called the Pediatric Quality of Life InventoryTM 4.0 Generic Core Scales (PedsQLTM-GCS), a survey that includes questions on physical, emotional and social functioning as well as school performance. The team concluded that EPO increases Hb levels in children with anemia, reduces their need for transfusions and improves the quality of life in those who have an increase in Hb.

Source: Euekalert
'"/>




Related medicine news :

1. New Way to "See" Genes, Evaluate Effectiveness of Gene Therapies Discovered
2. Inhaled Steroids Safe & Effective for Children with Asthma
3. ZD1839 Proves Effective - A Breakthrough in fighting Lung Cancer
4. Fluoride Found Effective in Osteoporosis
5. Aspirin and Warfarin Are Equally Effective for Stroke Prevention
6. Implantable Contact Lens Found Safe and Effective
7. Effective And Economical Agent For Anthrax
8. Stem Cell Transplants May Be Effective For MS Patients
9. Effective therapy for Huntingtons disease
10. Chemotherapy Effective for Bladder Cancer
11. Drug Effective for Vascular Dementia
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/22/2017)... (PRWEB) , ... February 22, 2017 , ... ... its certification exam and eligibility requirements effective with the April 2017 testing period. ... 1995. , “The Care Manager Certified (CMC) exam is periodically re-calibrated to ...
(Date:2/22/2017)... ... February 22, 2017 , ... In a ... skipping doses or not filling a prescription because they could not afford to ... problems getting medications were 30-60%*. At the same time, hospitals, pharmacies, ...
(Date:2/22/2017)... Colorado (PRWEB) , ... February ... ... the availability of their newest advanced absorption cannabidiol (CBD) serum, “NANOCALM 300” ... delivery system®, which provides instant absorption from the mouth into the bloodstream. ...
(Date:2/22/2017)... WV (PRWEB) , ... February 22, 2017 , ... ... awarded a contract to Quality Insights to help small practices in Delaware, New ... Payment Program, established by the Medicare Access and CHIP Reauthorization Act of 2015 ...
(Date:2/22/2017)... ... February 22, 2017 , ... Michael ... new media platform connecting healthcare technology professionals and other key stakeholders with an ... quarterly publication starting on March 1, announced Michael J. Hennessy, Jr., president of ...
Breaking Medicine News(10 mins):
(Date:2/22/2017)... -- Andre, DiMino, CEO of ADM Tronics Unlimited, Inc. (OTCQB: ... and products, commented on ADMT,s third quarter fiscal year ... the Company,s quarterly report on Form 10Q available at ... stated "During the quarter ended December 31, 2016 we ... portion of our engineering efforts into the development of ...
(Date:2/22/2017)... , Feb. 22, 2017 Summary ... infarction partnering deals and agreements entered into by ... full report: http://www.reportlinker.com/p03605670-summary/view-report.html Description The ... understanding and access to partnering deals and agreements ... - Trends in partnering deals ...
(Date:2/22/2017)... 22, 2017 Summary Provides ... partnering deals and agreements entered into by the ... report: http://www.reportlinker.com/p03605673-summary/view-report.html Description The Global ... understanding and access to partnering deals and agreements ... - Trends in partnering deals ...
Breaking Medicine Technology: