Navigation Links
Drugs disrupt formation of blood vessels

Scientists have made a signficant step forward in their attempt to starve cancer tumours by stopping the growth of the blood vessels that feed them nutrients. Four drugs that disrupt angiogenesis - blood vessel formation - have been shown for the first time to be effective. It also provides the first indication that the drugs, known as angiogenesis inhibitors, vary in effectiveness depending on the stage of cancer targeted.

// Senior researcher Dr Douglas Hanahan, professor of biochemistry at the University of California in San Francisco, USA, said: " We've shown that these drugs have beneficial effects when used to treat mice developing organ-specific cancer ". The work on mice is significant because scientists believe it closely mirrors the conditions found in human tumours. Mice used in the study were genetically engineered to produce a form of cancer of the pancreas.

The scientists tested drugs to see if they could stop the signals that are emitted to trigger the formation of the blood vessels that fuel the growth of tumours. Four compounds, known as AGM-1470, BB-94, angiostatin and endostatin, together with a combination of the last two, were tested.

They found that if administered early enough all the drugs prevented the tumour from triggering the formation of blood vessels in more than half the cases where it should have occurred. All four drugs were effective, impairing growth by between 60% and 88%. Dr Hanahan said: "Our findings are encouraging about the potential value of angiogenesis inhibitors for treating cancer; we believe we can do even better."


'"/>




Page: 1

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
3. Nasal Spray Could Take Drugs Direct to Brain.
4. Emphasis to ban Drugs ads by Doctors
5. Osteoporosis Drugs: right time to take-off
6. Drugs to stop burgeon of HIV
7. Misleading Advertisements for Prescription Drugs
8. Drugs For Anthrax May Interfere With Oral Contraceptives
9. Over-The-Counter Drugs May Prevent Alzheimers
10. Steps To Improve Quality Of Plant-Based Drugs
11. Nasal Spray Could Take Drugs Directly to Brain
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... “America On ... Christian identity. “America On The Brink” is the creation of published author, William ... several great-grandchildren. As a WWII veteran, he spent thirty years in the Navy. ...
(Date:10/12/2017)... ... 12, 2017 , ... Planet Fitness, one of the largest and fastest growing ... open a flagship location in Covington, LA at 401 N. U.S. Highway 190, in ... to Office Depot in the Holiday Square shopping center. Its location allows it to ...
(Date:10/12/2017)... MD (PRWEB) , ... October 12, 2017 , ... The ... of Excellence to Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual ... – 8. , In honor of Morris F. Collen, a pioneer in the field ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... has recently contributed a medical article to the newly revamped Cosmetic Town ... article spotlights the hair transplant procedure known as Follicular Unit Extraction ...
(Date:10/12/2017)... ... 2017 , ... On Saturday, October 21, the Health & Wellness Center at ... raise money for the American Heart Association Heart Walk. Teams of up to 10 ... to keep their treadmills moving for 5 hours. Treadmills will start at 7:00 p.m. ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... , Oct. 2, 2017  Eli Lilly and ... financial results for the third quarter of 2017 on ... conference call on that day with the investment community ... The conference call will begin at 9 ... can access a live webcast of the conference call ...
(Date:10/2/2017)... 2017 Halo Labs announces the European launch of their ... HORIZON at MIBio 2017 in Cambridge, U.K ... matter in biopharmaceutical samples with unprecedented speed and sensitivity while using ... Backgrounded Membrane Imaging. ... subvisible particle analysis system ...
(Date:9/28/2017)... Hill-Rom Holdings, Inc. (NYSE: HRC), will host ... webcast on Friday, November 3, 2017, beginning at 7:00 ... approximately 8:30 a.m. (CDT) / 9:30 a.m. (EDT). ... performance and guidance for 2018, Hill-Rom executives will also ... performance, and long-range financial outlook through 2020. ...
Breaking Medicine Technology: