Navigation Links
Drugs disrupt formation of blood vessels

Scientists have made a signficant step forward in their attempt to starve cancer tumours by stopping the growth of the blood vessels that feed them nutrients. Four drugs that disrupt angiogenesis - blood vessel formation - have been shown for the first time to be effective. It also provides the first indication that the drugs, known as angiogenesis inhibitors, vary in effectiveness depending on the stage of cancer targeted.

// Senior researcher Dr Douglas Hanahan, professor of biochemistry at the University of California in San Francisco, USA, said: " We've shown that these drugs have beneficial effects when used to treat mice developing organ-specific cancer ". The work on mice is significant because scientists believe it closely mirrors the conditions found in human tumours. Mice used in the study were genetically engineered to produce a form of cancer of the pancreas.

The scientists tested drugs to see if they could stop the signals that are emitted to trigger the formation of the blood vessels that fuel the growth of tumours. Four compounds, known as AGM-1470, BB-94, angiostatin and endostatin, together with a combination of the last two, were tested.

They found that if administered early enough all the drugs prevented the tumour from triggering the formation of blood vessels in more than half the cases where it should have occurred. All four drugs were effective, impairing growth by between 60% and 88%. Dr Hanahan said: "Our findings are encouraging about the potential value of angiogenesis inhibitors for treating cancer; we believe we can do even better."


'"/>




Page: 1

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
3. Nasal Spray Could Take Drugs Direct to Brain.
4. Emphasis to ban Drugs ads by Doctors
5. Osteoporosis Drugs: right time to take-off
6. Drugs to stop burgeon of HIV
7. Misleading Advertisements for Prescription Drugs
8. Drugs For Anthrax May Interfere With Oral Contraceptives
9. Over-The-Counter Drugs May Prevent Alzheimers
10. Steps To Improve Quality Of Plant-Based Drugs
11. Nasal Spray Could Take Drugs Directly to Brain
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... ... 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic ... World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. ... some of the world’s leading providers of cereal and other breakfast foods. Its residents ...
(Date:6/26/2016)... Cary, North Carolina (PRWEB) , ... June 26, 2016 , ... ... the release of a new product that was developed to enhance the health of ... harvested for centuries. , The two main herbs in the PawPaws Cat Kidney ...
(Date:6/26/2016)... Lake Orion, Clarkston, Michigan (PRWEB) , ... June ... ... direction with respect to fertility once they have been diagnosed with endometriosis. These ... tolerable intercourse but they also require a comprehensive approach that can help for ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, ... Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. ... skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was ...
(Date:6/25/2016)... ... 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users can ... CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn ... X . Simply select a ProHand generator and drag it above media or text ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... -- According to a new market research ... Safety Pen Needles), Needle Length (4mm, 5mm, 6mm, 8mm, ... Purchase (Retail, Non-Retail) - Trends & Global Forecasts to ... for the forecast period of 2016 to 2021. This ... 2021 from USD 1.65 Billion in 2016, growing at ...
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, ... less invasive and more durable cerebrospinal fluid treatments, ... funding.  The Series-A funding is led by Innova ... Fund, and other private investors.  Arkis, new financing ... instrumentation and the market release of its in-licensed ...
(Date:6/23/2016)... 23, 2016 Any dentist who has made an ... current process. Many of them do not even offer this ... and high laboratory costs involved. And those who ARE able ... such a high cost that the majority of today,s patients ... Parsa Zadeh , founder of Dental Evolutions Inc. and ...
Breaking Medicine Technology: