Navigation Links
Drug to Delay the Onset of Arthritis

Arthritis is a common health problem worldwide. Both osteoarthritis and rheumatoid arthritis cause joint pain and stiffness in patients.There is no cure for arthritis and no effective treatment to repair damaged cartilage. //

A new study could help lead doctors towards a drug to prevent the onset of arthritis. The research pinpoints the molecular pathway and an enzyme that play a pivotal role in the onset of the condition. Researchers from Cardiff University conducted research to better understand the molecular pathway involved in the onset of arthritis.

Early research has shown activity levels of two enzymes, MMP-2 and MMP-9, are frequently increased in the cartilage of people suffering from osteoarthritis. Researchers also know, in patients with arthritis, the cartilage releases a substance called proteoglycan. Scientists cultured cartilage cells in vitro to study this pathway as osteoarthritis develops.

The researchers stimulated the cells with two molecules that activate the arthritis processes. This caused the increased release of proteoglycan and the production and activation of MMPs. Researchers then inhibited the enzyme PKR in the cells. This time they found no increase in the activation of MMPs and that the release of proteoglycan was significantly reduced.

Researchers say the results of this study imply that PKR is involved in the molecular pathways that are implicated in the progression of arthritis. They hope this understanding will help in the discovery of novel targets for arthritis drugs.
'"/>




Page: 1

Related medicine news :

1. Smoking Delays Pregnancy
2. Delaying Parkinson’s Diseas
3. Lifestyle changes Can Delay the Onset Of Dementia
4. Lifestyle changes Can Delay the Onset Of Dementia
5. Lifestyle changes Can Delay the Onset Of Dementia
6. A Vitamin A Day May Delay The Life span Of HIV Patients
7. Delaying The Progression Of Alzheimer’s Disease
8. The Effects Of Delaying A Delivery Questioned
9. Delaying pregnancy may lessen life expectancy of the child
10. In Early Epilepsy Delay in medications Recommended
11. Delay medicine for early epilepsy, says scientists
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/19/2017)... Viejo, CA (PRWEB) , ... February 19, 2017 , ... ProBrand Glitch is a set ... . With ProBrand Glitch users can easily reveal any logo with a glitch reveal in ... X users control over the style and animation of each preset. Use these presets to ...
(Date:2/18/2017)... , ... February 17, 2017 , ... ... source of disruptive innovation in the industry, according to the recent NEJM Catalyst ... based on surveys of the NEJM Catalyst Insights Council, a qualified group of ...
(Date:2/18/2017)... ... February 18, 2017 , ... ... Pixel Film Studios ’ ProParagraph Fashion Volume 2 for all multi-line FCPX ... applications. Users can pick and choose from hand-crafted trend-setting designs with smooth ...
(Date:2/17/2017)... ... February 17, 2017 , ... The Alliance Healthcare Foundation ... to further positively impact the health and wellness of our community in San ... our duty to seriously consider releasing our assets beyond our 5% targeted distribution ...
(Date:2/17/2017)... Verdes, CA (PRWEB) , ... February 17, 2017 ... ... emotional flow is Dr. Carol Francis' goals for each and every ... Conference, Dr. Carol Francis will demonstrate five different brainwave tools which help energize ...
Breaking Medicine News(10 mins):
(Date:2/20/2017)... 20, 2017  Today from HIMSS17, Ambra Health ... suite, announced the launch of  Ambra for Developers ... Built around modern, RESTful web-services, this is the first ... With these new APIs, IT departments at health ... data into other applications such as population health or ...
(Date:2/20/2017)... Feb 20, 2017 Research and Markets ... Global Market -Forecast to 2022" report to their offering. ... ... in aging population, rising adoption of tension free repair procedures ... growth of hernia repair devices global market. However, Inconsistent reimbursement ...
(Date:2/20/2017)... Feb. 20, 2017  There has been a paradigm ... (NCDs) across sub-Saharan Africa, which in turn is driving ... of more Western lifestyle diseases such as cardiovascular disease ... infectious and parasitic illness, will present the pharmaceutical industry ... opportunity of $40.8 billion in 2019. "An ...
Breaking Medicine Technology: