Navigation Links
Drug increases hemoglobin in Myelodysplastic Syndrome

Patients with Bone marrow disorder Myelodysplastic Syndrome (MDS), treated with 500 mcg of Aranesp (Darbepoetin alfa) for every three weeks found to improve the hemoglobin content in 70% of patients. //The new drug Aranesp is manufactured by Amgen Biotech, which conducted a Phase II trial with 200 low-risk MDS patients who were administered with 500 mcg of Aranesp every three weeks. MDS is a pre-leukemia stage in which the bone marrow does not produce the required blood cells. MDS is associated with abnormal blood counts resulting in anemia (low red blood cell count), Neutropenia (low white blood cell count) and Thrombocytopenia (low blood platelet count).

Professor Janice Gabrilove, Medical Oncologist, Mount Sinai School of Medicine, New York said that, “During the course of their disease, the majority of MDS patients develop clinically significant anemia, which can lead to fatigue and the need for red blood cell transfusions currently, there are no recombinant erythropoietic products approved for the treatment of anemia in MDS patients."

The Phase II trial was conducted for 13 weeks and their erythroid response was evaluated by measuring the hemoglobin, 70 percent of patients had an erythroid response, with 49 percent classified as major response , 67% of patients achieved the target hemoglobin level of 11 g/dL. 19% in the erythropoietin-naive group had at least one transfusion during the 13-week observation period. In the group previously treated with an erythropoietic agent (n= 59), 44 percent experienced an erythroid response, with 24 percent classified as major. Forty-five percent of patients achieved the target hemoglobin level of 11 g/dL, and 29 percent had at least one transfusion.

Source: Eurekalert.


'"/>




Page: 1

Related medicine news :

1. Human gene number increases
2. Stress response increases suicide risk
3. Sleep apnoea increases post-operative risks
4. Vaginosis increases risk of miscarriage
5. Serotonin increases stroke risk
6. Depression increases heart attacks
7. Excess vitamin A increases fracture risk
8. High vitamin A increases risk of hip fractures
9. Less sleep increases mortality rates
10. Smoking during pregnancy increases risk of cleft palate
11. Obesity increases health costs
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/20/2017)... , ... September 20, 2017 , ... ... Maintain® methodology and industry-leading compliance software, The Guard®, has helped another long-time client ... (OCR) HIPAA audit and properly satisfy the law. , Thanks to the help ...
(Date:9/20/2017)... (PRWEB) , ... September 20, 2017 , ... ... digital and social campaign, “Humans With Vaginas.” The goal is to ignite conversation ... of non-toxic personal care products. The brand has declared September “Humans with Vaginas” ...
(Date:9/20/2017)... ... 20, 2017 , ... Medicare doesn’t have the authority to ... for their prescription drugs, according to a new comparison of drug plans by ... behalf, there’s no consistency in drug pricing among drug plans,” states TSCL’s Medicare ...
(Date:9/20/2017)... ... ... “The Trials I Face to Receive God’s Grace”: a mesmerizing take on ... to better one’s life through God. “The Trials I Face to Receive God’s Grace” ... places, found a love for writing. Green feels that expressing his feelings through prayer ...
(Date:9/20/2017)... ... ... Houston, Texas, investment firm CORDA Investment Management, LLC, believes in giving back. ... work and rolled up their sleeves to help with relief efforts. The team picked ... process of rebuilding. , CORDA founder Bonner C. Barnes notes that investment management firms ...
Breaking Medicine News(10 mins):
(Date:9/5/2017)... , Sept. 5, 2017  Just 18 months ... Insight is pleased to announce the appointment of three ... Tammy Wynne , Dominic Jones-Phillips and ... industry. Tammy ... team of market access writers. She has over ten ...
(Date:9/1/2017)... Ind. , Sept. 1, 2017  Explorers Like Us ... capture America,s greatest aural experiences — and deliver these experiences ... experience to help people feel and heal better. ... While nothing beats a ... and refresh your mind, Life Environments™ is the next best ...
(Date:8/29/2017)... Va. , Aug. 29, 2017 ivWatch, LLC, the ... peripheral IV infiltrations, announced it has been awarded an Innovative Technology ... company in the country. ... continuous monitoring device to aid in the early detection of peripheral ... The Innovative ...
Breaking Medicine Technology: