Navigation Links
Drug for Blood Pressure also Treats Lung Cancer

tensin-converting enzyme (ACE) inhibitors. These drugs, which include Capoten? and Lotensin?, increase levels of angiotensin-(1-7) in the bloodstream.

Gallagher and Tallant have been working with angiotensin -(1-7) for years as members of the Hypertension and Vascular Research Center faculty. Carlos M. Ferrario, M.D., center director, discovered angiotensin-(1-7) in 1988, and found it to be a critical element of the blood pressure control system. The hormone relaxes (dilates) the walls of the blood vessels, causing blood pressure to be lowered. ACE inhibitors may work by increasing angiotensin-(1-7).

For the current study, human cancer cells were obtained from the American Tissue Culture Collection. Mice were inoculated with the cells and 32 days later were randomly selected to receive either an intravenous treatment of angiotensin-(1-7) or saline for 28 days. The blood levels of angiotensin-(1-7) achieved through treatment were similar to levels in humans being treated with an ACE inhibitor.

'The study may explain the molecular mechanism for a decreased risk of lung cancers in patients with high blood pressure taking ACE inhibitors,' said Tallant.

The researchers believe that angiotensin-(1-7) reduces cyclooxygenase-2 (COX-2), an enzyme that regulates cell growth. COX-2 is found at higher levels in 70 to 90 percent of malignant lung tumors.

Theoretically, drugs to reduce COX-2 would also be effective at shrinking tumors. But the drugs, such as Vioxx?, have been shown to increase the risk of heart attack, stroke and angina.

The researchers said that additional studies of angiotensin-(1-7) are needed, but that the hormone shows promise as a lung cancer treatment – either alone or in combination with other drugs.

Source-Eurekalert
'"/>




Page: 1 2

Related medicine news :

1. Recommendations for Treatment of Blood Pressue
2. Blood Cells Capable of Regenerating Liver
3. Blood clots likely in long travel
4. Hemochromatosis Patients Blood is Safe
5. Blood transfusions beneficial after heart attacks
6. Blood Pressure Drug may slow wasting in burn victims
7. Levels Of Blood Proteins May Help Heart Disease Care
8. Blood test may identify ovarian cancer
9. A Blood test for suicide risk?
10. Blood Pressure Drugs maintain muscle strength
11. Blood test diagnoses heart failure in short time
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Drug for Blood Pressure also Treats Lung Cancer

(Date:3/2/2015)... While many hospitals have implemented medical interpretation ... Rights Act, the unique needs of children with limited ... to the value of video remote interpreting (VRI) services. ... 20 U.S. children have LEP—a number that rises to ... Stratus Video Interpreting enables healthcare providers and ...
(Date:3/2/2015)... (PRWEB) March 02, 2015 Gummy smile ... reshaping procedures. Gum reshaping can involve one or several procedures ... regenerate lost gum tissue for a more even gum line. ... gum line treatment that can permanently lighten discolored or ... smile approach, which involves a personalized treatment plan to address ...
(Date:3/2/2015)... March 02, 2015 New York ... Unplugged™—will be delivering a plenary address entitled Finding ... the Art of Healing and Recovery at this ... Behavioral Healthcare Executive Summit (BHES).     , With more ... songs have been recorded by some of the ...
(Date:3/2/2015)... 2015 The minimally invasive surgical ... CAGR of 6.1% to reach $14,133.0 million by ... Factors such as advantages of minimally invasive surgeries ... to minimally invasive surgeries and increasing number of ... the global minimally invasive surgical instruments market. , ...
(Date:3/2/2015)... Washington, DC (PRWEB) March 02, 2015 ... the publication of AIS’s Directory of Health Plans: ... comprehensive resource available on the U.S. health plan market, ... operating in the United States. , Available as ... “Executive Summary” of enrollment trends in quick-view tables and ...
Breaking Medicine News(10 mins):Health News:Stratus Video Addresses Inadequate Language Interpreting for 2.4 Million U.S. Children 2Health News:Stratus Video Addresses Inadequate Language Interpreting for 2.4 Million U.S. Children 3Health News:Stratus Video Addresses Inadequate Language Interpreting for 2.4 Million U.S. Children 4Health News:Gummy Smile Expert, Dr. Alex Farnoosh, is Now Offering Gum Reshaping Procedures 2Health News:Richie Supa Announced as a Plenary Speaker at NCAD 2015 2Health News:Minimally Invasive Surgical Instrument Market - Global Forecast to 2019 - New Report by MarketsandMarkets 2Health News:Now Available from AIS: 12th Edition of Annual Book Containing Health Plan Enrollment Data, Contact Information 2
... AIDS Alliance Fund, WASHINGTON, Sept 24 Today ... new proposal,for what the US needs to do next ... To address the crisis outside the US, Senator Edwards, ... to prevention and,treatment. He provides a strong emphasis on ...
... Cosmetic Dermatology Organization Urges Consumers to ... ... the American Society of Cosmetic Dermatology and Aesthetic,Surgery (ASCDAS), responded to the ... State Board of Healing Arts to ban the,liposuction treatment, Lipodissolve. "This procedure ...
... be successful, PITTSBURGH, Sept. 24 For ... be the path to becoming smoke-free. While,there are ... a new national,survey conducted by Nicorette Cinnamon Surge ... an advance plan.(1) In fact, half (49,percent) of ...
... RIVER, N.Y., Sept. 24 Wyeth (NYSE: WYE ... Pearl River, N.Y.,research and manufacturing facility, honoring the generations ... advances in medical science,and human health. The 550-acre ... New York City, employs approximately 3,200 people and is ...
... 24, 2007 -- A new study reports important ... those diagnosed with schizophrenia. Schizophrenia is considered ... psychiatric disorders, which has three distinct facets, often ... emotions, reduced capacity for pleasure), and cognitive (impairments ...
... Introduces its proprietary PhreesiaPad The ... SAN DIEGO and NEW YORK, Sept. 24 ... company to offer a free patient check-in,solution in ... to automating the check-in process, Phreesia delivers fully,interactive ...
Cached Medicine News:Health News:Edwards' Plan on AIDS Unveiled Today 2Health News:Lipodissolve - Is it Safe??? 2Health News:Photos: New Survey Shows Many Successful Quit Smoking Attempts Made Without Advance Planning 2Health News:Photos: New Survey Shows Many Successful Quit Smoking Attempts Made Without Advance Planning 3Health News:Photos: New Survey Shows Many Successful Quit Smoking Attempts Made Without Advance Planning 4Health News:Wyeth's Pearl River, N.Y. Facility Celebrates 100 Years of Achievements in Health care 2Health News:Wyeth's Pearl River, N.Y. Facility Celebrates 100 Years of Achievements in Health care 3Health News:Wyeth's Pearl River, N.Y. Facility Celebrates 100 Years of Achievements in Health care 4Health News:Potential new approach to treat cognitive impairments in schizophrenia 2Health News:Phreesia Launches at DEMOfall 07 2Health News:Phreesia Launches at DEMOfall 07 3
(Date:3/2/2015)... Mount Elizabeth Novena Hospital will soon become ... to treat cancer using the TrueBeam™ STx system ... VAR ).  At a Grand Opening event ... advanced forms of treatment including radiosurgery, a precise method ... a tumor from outside the body, without performing surgery.  ...
(Date:3/2/2015)... , March 2, 2015 Valencia Technologies Corporation ... patient with its radically small device for the ... early results in this randomized, double-blinded, controlled trial are ... of confidence that it will succeed in a large ... early clinical results, Valencia has ...
(Date:3/2/2015)... SAN FRANCISCO, Calif. , March 2, 2015 ... for the treatment of cancer, today announced the ... of leading researchers and clinicians in the fields ... The new advisory boards will provide ... wholly owned pipeline of precision immunotherapies and Probody ...
Breaking Medicine Technology:Mount Elizabeth Novena Hospital to Deliver First TrueBeam STx Radiosurgery Treatments in Singapore 2Mount Elizabeth Novena Hospital to Deliver First TrueBeam STx Radiosurgery Treatments in Singapore 3Valencia Technologies Implants its 48th Patient, Continues Equity Crowdfunding 2CytomX Expands Scientific and Clinical Advisory Boards with Leading Experts in Cancer Immunotherapy and Antibody Drug Conjugates 2CytomX Expands Scientific and Clinical Advisory Boards with Leading Experts in Cancer Immunotherapy and Antibody Drug Conjugates 3
... 2, 2011 Men who take non-steroidal anti-inflammatory drugs three ... times more likely to have erectile dysfunction compared to men ... Kaiser Permanente study published online in The Journal of ... trend toward this same finding, this observational study used electronic ...
... SILVER SPRING, Md., March 2, 2011 The U.S. ... that manufacture, distribute, or market certain unapproved prescription oral ... be legally marketed in the United States. ... cough, cold, and allergy drug products have not been ...
Cached Medicine Technology:Non-Steroidal Anti-Inflammatory Drugs Linked to Increased Risk of Erectile Dysfunction 2Non-Steroidal Anti-Inflammatory Drugs Linked to Increased Risk of Erectile Dysfunction 3FDA Prompts Removal of Unapproved Drugs From Market 2FDA Prompts Removal of Unapproved Drugs From Market 3
... Digital Multichannel, with it's streamlined ... of routine laboratory tasks. The ... features: Soft-touch tip ejection, Super ... (0.5-10ul models), Entire pipette autoclavable, ...
... wide variety of applications. • Whole pipette is ... freely rotated against the handle to work in ... angle towards the microtiter plate. • The special ... common pipette tips, and provides a firm, parallel ...
... to operate in a wide variety of applications. ... The manifold can be freely rotated against the ... always at an optimum angle towards the microtiter ... the use of most common pipette tips, and ...
... Features and Benefits: 1-8channel ... a new product number, created ... number. If showing no availability ... old Sigma-Aldrich number (Z37,174-2) or ...
Medicine Products: