( 0 cardiac surgery patients having a pro...)Drug Used in Coronary Artery Bypass Surgery may Increase Risk of Death,Health

0 cardiac surgery patients having a profile similar to patients in our study. For such patients, our study found a 5-percent absolute increase in five-year mortality (1 percent per year for five years) associated with aprotinin use, compared with either aminocaproic or tranexamic acid use."

"These findings indicate that in addition to the previously reported acute renal and vascular safety concerns, aprotinin use is associated with an increased risk of long-term mortality following CABG surgery. Use of aprotinin among patients undergoing CABG surgery does not appear prudent because safer and less expensive alternatives (i.e., aminocaproic acid and tranexamic acid) are available," the authors conclude.

Source-Eurekalert
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