Navigation Links
Drug Eluting Nanostructured Coatings Enable Targeted Drug Therapy for Orthopedic Patients

Drug delivery systems have progressed from the teaspoon to time-release capsules to drug-eluting stents .

Nanotechnology promises yet another advance by delivering therapeutic agents at desired rates exactly where needed in the body.

In a paper presented at the NSTI Nanotech 2007 Conference, researchers at the University of California, San Francisco demonstrate how they have created nanotubes from biocompatible metal oxides that can hold therapeutic proteins or drugs and deliver these agents in a highly-controlled manner.

The fabrication strategies developed by the authors is flexible in terms of controlling the diameter and length scales of the tubes. By changing these physical parameters of nanotubes, they could precisely control the dosage and deliver drugs at physiological rates for desired duration of time.

In the case of orthopedic implants with nanotubes on the implant surfaces, drugs such as antibiotics can be loaded in the tubes and released right at the site of implantation. This method, which targets the drug where it is needed, can avoid the side effects due to high dosages normally given to patients. Further, in cases where a very long treatment regimen is needed, such as in growth factor therapy, nanotubes may provide superior performance.

According to Ketul C. Popat, "When a person has an orthopedic implant surgery, they normally will have to take antibiotics and growth factors either orally or by injection. There are several side effects associated with taking drugs this way which can be very painful for the patient.

However, by placing the drugs on to the surface of these implants, we can deliver them right where they are needed and can avoid larger doses and side effects. The nanostructured coating on the implant surface helps the drug to maintain its bioavailability as well as deliver the drugs at physiological rates for a desired duration of time."


'"/>




Page: 1

Related medicine news :

1. Drug-Eluting Stents Ensure Patency Of The Saphenous Vein Grafts
2. Poor Andhra Women Enable Bypass Surgery Paying 50 Paise Each
3. Small Biosensor To Enable Cancer Detection
4. New Technique Enables Better Nursing Of Robin Sequence Infants
5. Bad Enzymes Found To Enable Brain Recovery Following Stroke
6. Decision-Making Enabled By Neurons: Value Assigned To Available Choices.
7. Micro vascular Disease Enabled with a Superior Test, Courtesy: Women’s Heart Progra
8. Glucose Enables Speedy Recovery From Malaria
9. Single Sugar Enables Antibody to Treat Inflammation
10. Cochlear Implants in Both Ears Enables Better Hearing
11. Electronic Nerve Stimulator Enables Walking
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... 2017 , ... The American Board of Family Medicine's (ABFM) Board of Directors ... Officer, succeeding Dr. James C. Puffer upon his retirement. Dr. Newton will serve in ... retirement at the end of 2018. Upon assuming the role of President and CEO ...
(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a leading Health and Nutrition ... the Purzorb™process to full spectrum CBD oil will revolutionize the rapidly growing CBD market ... can be easily incorporated into liquid products, while reducing costs to end users. , ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Lori R. Somekh, ... member of ElderCounsel, a national organization of elder law and special needs planning attorneys. ... and rules. It also provides a forum to network with elder law attorneys nationwide,” ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance ... care insurance companies have a waiver for care if the client has a cognitive ... the family pays for care, is often waived, so the benefits from their insurance ...
(Date:10/13/2017)... NY (PRWEB) , ... October 13, 2017 , ... Ellevate ... people in business to advocate for action towards gender equality at their inaugural Summit ... from around the globe, and reached a social audience of over 3 million. To ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... , Sept. 25, 2017  EpiVax, Inc., a ... design, and immune-engineering today announced the launch of ... development of personalized therapeutic cancer vaccines. EpiVax has ... exclusive access to enabling technologies to the new ... will lead EpiVax Oncology as Chief Executive Officer. ...
(Date:9/22/2017)... 22, 2017 AVACEN Medical (AVACEN) announced that ... successfully helping those with the widespread pain associated with ... Amanda in Essex, England commented, ... hair, experiencing no sleep at all, tremendous pain, with ... cannot recommend [the AVACEN 100] enough, how this has ...
(Date:9/18/2017)... , Pa. and KALAMAZOO, Mich. , ... Allentown, Penn. , and OptiMed Specialty Pharmacy of ... business partnership to offer a strategic hub service that ... Healthcare,s highly sought-after personal spirometer, Spiro PD 2.0, and ... A spirometer is a medical device used to ...
Breaking Medicine Technology: