Navigation Links
Drug Company Halts Late-Stage Trial of Sickle-Cell Disease Drug

Drug manufacturer Icagen announced that it has ended its Phase III clinical trial of its sickle-cell treatment senicapoc, citing lack of effectiveness//, the Raleigh News & Observer reports.

Sickle-cell disease is a genetic blood disorder primarily affecting blacks, but can also be found Hispanics and people from the Middle East, Southeast Asia and the Mediterranean region.

Final testing in the 160-participant senicapoc study began in February 2005, and concerns about the treatment's effectiveness arose in August 2006 after the study's data monitoring committee suggested that senicapoc likely would benefit only a small number of people.

Icagen and Johnson & Johnson -- which paid $15 million to market and help develop the drug -- at that point decided to adjust the number of participants and treatment options being tested in the trial.

Recently, the committee said preliminary trial data show that senicapoc does not prevent chronic pain, one of the disease's most prominent complications. However, the drug consistently has been able to reduce the number of deformed blood cells associated with the disease. That effect "might make the drug suitable to reduce elevated blood pressure in the lungs of some sickle-cell patients and the stroke risk for pediatric sickle-cell patients," according to the News & Observer.

Currently, there is only one other treatment available for the disease. Richard Katz, Icagen's senior vice president of finance and corporate development, said that despite the findings, "it would be premature to say senicapoc is dead." He said the drug's future should be clearer in a few months.

Source-Kaiser Family Foundation/M
'"/>




Page: 1

Related medicine news :

1. Problems Of a Growing Company
2. Teenagers Take More Risk-Taking Behaviors In The Company Of Same Sex Friends
3. Australian Company Gets $10 million For Developing Skin Cancer Gel
4. Elderly People Prefer The Company Of Pet Dogs
5. Ossur Acquires the U.S. Orthopaedics Company
6. Britain Approves Indian Company For Supplying Medicines
7. Drug Company Admits Knowledge Of Side Effects In Monkeys
8. Ranbaxy Expands By Acquiring A Generic Company In Belgium
9. Indian Training Company To Train Children In Dubai, Sharjah
10. GE Healthcare to Acquire Swedish Medical Company
11. Drug Company Seeks Approval for Human Testing of Vaccine against H5N1 Virus
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/3/2016)... ... May 03, 2016 , ... AvePoint, ... release of DocAve 6 Service Pack (SP) 7, the enterprise-class infrastructure ... 2016 and take advantage of the platform’s latest features – whether in an ...
(Date:5/3/2016)... ... May 03, 2016 , ... LunchSkins is changing the future of ... of single-use, throw away plastic baggies. The mission-driven bags give back to global leaders ... “The LunchSkins mission is all about reducing global plastic waste and we’ve ...
(Date:5/2/2016)... ... May 03, 2016 , ... ... FDA approved sSOIP telemedicine stethoscope software that enables the stethoscope stream to go ... PCP-SSP and works with RNK’s flagship PCP-USB stethoscope. , Remote auscultation involves two ...
(Date:5/2/2016)... ... ... As directed by its board of directors during its April 26 meeting, The ... nurse practitioners (CNP) to practice to the full scope of their license without the ... and 3,600 hours. , In addition, HAP supports CNPs who are licensed in another ...
(Date:5/2/2016)... (PRWEB) , ... May 02, 2016 , ... ... educational website to help consumers better understand life insurance throughout various life stages. ... including an easy-to-use life insurance needs calculator and content specific to the times ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... ORANGE COUNTY, Calif. , April 29, 2016 ... technology industry is projected to shift from systems ... can replace all types of modality CRT Medical ... set-up." Although there are a host of foreseeable ... a serious concern; will existing modalities have to ...
(Date:4/29/2016)... 2016 Interview ... Sanofi, leader mondial et diversifié ... pour le premier trimestre 2016. Le ... commente les résultats du premier trimestre ... le reste de l,année. ...
(Date:4/28/2016)... 2016   Click here for supplemental information ... DPLO), the nation,s largest independent specialty pharmacy, announced ... to acquire Valley Campus Pharmacy, Inc., doing business ... specialty pharmacy that provides individualized patient care, based ... In 2015, TNH generated approximately $400 million in ...
Breaking Medicine Technology: