Navigation Links
Drinks and Breast Cancer – How It Happen

This bit of information may be a life saver for today’s urban woman, who thinks it cool, hip and what other cliché there is, to swig drinks at social gatherings or home,// alone, like she was to the wine glass or beer mug, born.

That breast cancer is linked to alcohol consumption is a well-established fact. Recent studies have shown that 60 percent of breast cancer cases can be traced to alcohol consumption. Yet, the how part, has always proved elusive for scientists. Not anymore, according to researchers of the University of Mississippi.

A study led by Dr. Jian-Wei Gu of the University of Mississippi Medical Center, which was presented at the American Physiological Society’s annual meeting shows exactly how alcohol consumption can lay the foundation for a woman to develop breast cancer.

The researchers fed normal 6-week old female mice with regular drinking water or water containing 1 percent alcohol, which is equivalent to about 2 to 4 drinks in humans (normal consumption rates for most people), for 4 weeks. In week 2, the animals were inoculated with mouse breast cancer cells, next to their mammary glands.

"We found after about 4 weeks that breast tumor size (averaging 1.5 g) almost doubled in mice that drank alcohol compared to control mice given plain water," Gu noted.

Along with this was a noteworthy increase in tumor blood vessels in mice that consumed alcohol, compared with those of no alcohol intake. The development of new blood vessels, called angiogenesis, is crucial to the development of tumor cells. These tumor cells require a profuse rush of oxygen and nutrients, which can be supplied to them only by new blood vessels, needed to sustain their rapid growth and proliferation. And this is the starting point of cancer development, say scientists.

As expected, there was also the significant increase of the key growth factor known as vascular endothelial growth factor or VEGF, in the tumors of the mice that consumed alcohol. VEGF incidentally, is needed for the formation of new blood vessels.

This study could conclude that moderate alcohol consumption stimulates the growth and progression of breast cancer by fueling the development of new blood vessels, mandatory for cancer cell growth. Says Gu: “VEGF can promote the formation of new blood vessels. This suggests that alcohol can induce tumor angiogenesis."

In other words, the scientists suggest the difference in tumor weight is a result of jacked-up growth in blood vessels due to alcohol consumption. That’s because when a rodent, or a human, gulps down a drink, the cells in their bodies go into overdrive to get rid of the “toxins.” The stressed-out cells then send out the hormone VEGF that stimulates the growth of blood vessels.

According to Gu, this study is the first of its kind to use an animal model that accurately mimics breast cancer. Previous studies injected human breast-cancer cells into “nude” mice, or those lacking an immune system. Without a line of defense, the mice’s bodies would let the foreign cells grow and scientists could run experiments.

“In regular mice, if you implant a human tumor, it won’t grow because it’s foreign [so the immune system would stage an attack],” says study team member Emily Young. That also meant any results would apply only to an organism lacking an immune system.

Instead, “we used regular mice and we implanted the mouse breast-cancer form into it,” Young added.

There have also been many studies, which used toxic levels of alcohol, leading to results that were less applicable to humans who typically don’t consume that much booze. The researchers say their results, unlike the others, can be squarely translated to humans and have implications to both prevent and help treat breast cancer.

“Normal people produce cancer cells every day,” Gu says, “but at the beginning the cancer doe sn’t have blood vessels.” This makes it easier for the body’s immune system to fend them off. Yet, once the cancerous cells acquire a blood-vessel lifeline, which this study suggests is set off by alcohol, the tumor growth succeeds.


Related medicine news :

1. Weight-Loss Drinks Can Make You Gassy
2. Sugar - Sweetened Drinks Found To Increase Risk of Diabetes
3. The Link Between Caffeine Drinks And Obesity
4. Obesity Can Be Caused By Consumption Of Energy Drinks
5. Soft Drinks May Reduce Esophageal Cancer Risk
6. Soft Drinks Can Strengthen Memory Power
7. High Levels Of Cancer Chemical Found In Soft Drinks
8. Soft Drinks May Be Banned In Rajasthan Schools
9. Tooth Enamel Eaten Away By Popular Drinks
10. Alcohol-illusion: Alcohol and Energy Drinks Combo, Maintains Sobriety?
11. Chemicals causing Cancer Found In Soft Drinks In UK
Post Your Comments:

(Date:11/30/2015)... (PRWEB) , ... November 30, 2015 , ... ... a new product dealer. Joining more than 30 HealthPostures’ dealers located throughout the ... space and increase the number of corporate, industrial, manufacturing and government workers and ...
(Date:11/30/2015)... ... 30, 2015 , ... Bayco Products, Inc today announced the introduction of three Nightstick® brand LED ... of three different colors; red ( NSP-1632 ), yellow ( NSP-1634 ) and blue ( ... in constant-on mode, or 27 hours in blinking strobe mode using a fresh set of ...
(Date:11/29/2015)... Lake Orion, Clarkston, Metamora, Michigan (PRWEB) , ... ... ... Women's Excellence is once again accredited by the American Institute of ... review process that allows practices to demonstrate that they meet or exceed ...
(Date:11/29/2015)... ... 29, 2015 , ... NewsWatch featured X-wing as part of its monthly Tech ... a technology expert and special reporter for NewsWatch, conducted the review and shared with ... It’s the future because flying cars are about to become a reality. Where’s the ...
(Date:11/29/2015)... ... 29, 2015 , ... Doctors who missed a case of mesothelioma in a ... mesothelioma and push for a diagnosis, especially in people exposed to asbestos. Surviving Mesothelioma ... read it now. , Researchers at Gifu Prefectural Tajimi Hospital in Japan ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... India , November 26, 2015 ... --> adds ... Report" and "Investigation Report on China ... and 2021 forecasts data and information ... . ...
(Date:11/26/2015)... , November 26, 2015 ... the addition of the  "2016 Future ... European Cell Surface Marker Testing Market: ...  report to their offering.  --> ... addition of the  "2016 Future Horizons ...
(Date:11/25/2015)... , Nov. 25, 2015  The American Academy ... Gynecologists (ACOG), and the March of Dimes cheered ... Protecting Our Infants Act of 2015 (S.799), ... of newborns born exposed to drugs, such as ... bill,s introduction, all three organizations have worked together ...
Breaking Medicine Technology: