Navigation Links
Drinks and Breast Cancer – How It Happen

This bit of information may be a life saver for today’s urban woman, who thinks it cool, hip and what other cliché there is, to swig drinks at social gatherings or home,// alone, like she was to the wine glass or beer mug, born.

That breast cancer is linked to alcohol consumption is a well-established fact. Recent studies have shown that 60 percent of breast cancer cases can be traced to alcohol consumption. Yet, the how part, has always proved elusive for scientists. Not anymore, according to researchers of the University of Mississippi.

A study led by Dr. Jian-Wei Gu of the University of Mississippi Medical Center, which was presented at the American Physiological Society’s annual meeting shows exactly how alcohol consumption can lay the foundation for a woman to develop breast cancer.

The researchers fed normal 6-week old female mice with regular drinking water or water containing 1 percent alcohol, which is equivalent to about 2 to 4 drinks in humans (normal consumption rates for most people), for 4 weeks. In week 2, the animals were inoculated with mouse breast cancer cells, next to their mammary glands.

"We found after about 4 weeks that breast tumor size (averaging 1.5 g) almost doubled in mice that drank alcohol compared to control mice given plain water," Gu noted.

Along with this was a noteworthy increase in tumor blood vessels in mice that consumed alcohol, compared with those of no alcohol intake. The development of new blood vessels, called angiogenesis, is crucial to the development of tumor cells. These tumor cells require a profuse rush of oxygen and nutrients, which can be supplied to them only by new blood vessels, needed to sustain their rapid growth and proliferation. And this is the starting point of cancer development, say scientists.

As expected, there was also the significant increase of the key growth factor known as vascular endothelial growth factor or VEGF, in the tumors of the mice that consumed alcohol. VEGF incidentally, is needed for the formation of new blood vessels.

This study could conclude that moderate alcohol consumption stimulates the growth and progression of breast cancer by fueling the development of new blood vessels, mandatory for cancer cell growth. Says Gu: “VEGF can promote the formation of new blood vessels. This suggests that alcohol can induce tumor angiogenesis."

In other words, the scientists suggest the difference in tumor weight is a result of jacked-up growth in blood vessels due to alcohol consumption. That’s because when a rodent, or a human, gulps down a drink, the cells in their bodies go into overdrive to get rid of the “toxins.” The stressed-out cells then send out the hormone VEGF that stimulates the growth of blood vessels.

According to Gu, this study is the first of its kind to use an animal model that accurately mimics breast cancer. Previous studies injected human breast-cancer cells into “nude” mice, or those lacking an immune system. Without a line of defense, the mice’s bodies would let the foreign cells grow and scientists could run experiments.

“In regular mice, if you implant a human tumor, it won’t grow because it’s foreign [so the immune system would stage an attack],” says study team member Emily Young. That also meant any results would apply only to an organism lacking an immune system.

Instead, “we used regular mice and we implanted the mouse breast-cancer form into it,” Young added.

There have also been many studies, which used toxic levels of alcohol, leading to results that were less applicable to humans who typically don’t consume that much booze. The researchers say their results, unlike the others, can be squarely translated to humans and have implications to both prevent and help treat breast cancer.

“Normal people produce cancer cells every day,” Gu says, “but at the beginning the cancer doe sn’t have blood vessels.” This makes it easier for the body’s immune system to fend them off. Yet, once the cancerous cells acquire a blood-vessel lifeline, which this study suggests is set off by alcohol, the tumor growth succeeds.

Sorce-Medindia
ANN/V
'"/>




Related medicine news :

1. Weight-Loss Drinks Can Make You Gassy
2. Sugar - Sweetened Drinks Found To Increase Risk of Diabetes
3. The Link Between Caffeine Drinks And Obesity
4. Obesity Can Be Caused By Consumption Of Energy Drinks
5. Soft Drinks May Reduce Esophageal Cancer Risk
6. Soft Drinks Can Strengthen Memory Power
7. High Levels Of Cancer Chemical Found In Soft Drinks
8. Soft Drinks May Be Banned In Rajasthan Schools
9. Tooth Enamel Eaten Away By Popular Drinks
10. Alcohol-illusion: Alcohol and Energy Drinks Combo, Maintains Sobriety?
11. Chemicals causing Cancer Found In Soft Drinks In UK
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/23/2017)... ... , ... The 89th Academy Awards will be celebrated this weekend, which means ... Bunkum Award. We invite you to enjoy our 11th annual tongue-in-cheek “salute” to the ... Center for American Progress (CAP), for its report, Lessons From State Performance on NAEP: ...
(Date:2/23/2017)... Chapel Hill, NC (PRWEB) , ... February 23, 2017 , ... ... the Platinum Sponsor for ACPA’s 74th Annual Meeting. KLS is a longtime supporter ... in 2017 as an exhibitor and Platinum Sponsor," said Dr. Bob Havlik, 2017 ACPA ...
(Date:2/23/2017)... ... February 23, 2017 , ... Rosica Communications, ... relations, content marketing, social media management, corporate communications, SEO and cause marketing, is ... and in nearby New Hampshire, Massachusetts and Canada, Rosica will focus on expanding ...
(Date:2/23/2017)... ... ... Dr. David Mahon leads Siena Dental, a comprehensive dental practice located at 10075 ... Patient Rated Henderson Dentist by Find Local Doctors earlier this year. ... who have earned high ratings and superior patient reviews from multiple credible sources. , ...
(Date:2/23/2017)... ... , ... Current Meditation , a new meditation concept ... U.S. starting this spring. Current Meditation focuses on “meditation for the modern world,” ... will be the first meditation concept in the U.S. offering franchising opportunities, setting ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... Im Rahmen seiner Schlüsselwachstumsstrategie arbeitet die Guian ... Provinz Guizhou, 2017 mit dem Angebot von Anreize schaffenden Strategien ... einer eingebetteten Hightech-Schlüsselindustrie. Foto - http://mma.prnewswire.com/media/471342/First_CRH__CHina_Railway_High_Speed__Train_Enters_Guian.jpg ... ... ...
(Date:2/23/2017)... New York , February 23, 2017 ... implications arising from increasing caseload for varicose veins in ... across the globe are prompting the adoption of endovenous ... study on global endovenous laser therapy market, ... towards aftereffects of lifestyle choices and consequences of obesity ...
(Date:2/23/2017)... -- As National Nutrition Month approaches, USA Medical is providing ... people live healthier lives by providing discounts on ... all 50 states including:  Texas Prescription Assistance Program ... Assistance Program . USA Medical also shares ... nutritious eating habits: Limit ...
Breaking Medicine Technology: