Navigation Links
Downstate Researchers Target Multiple Sclerosis

Researchers at SUNY Downstate Medical Center have developed a substance that inhibits the progress of multiple sclerosis (MS) in an animal model//. The agent, a novel calpain inhibitor, can be administered orally.

Calpains are a family of proteolytic enzymes naturally found in the human body. Inappropriate activation of calpain is associated with a number of neurodegenerative and autoimmune diseases such as MS. It is known to destroy the myelin sheath that coats and protects the nerves.

In a paper published in the Journal of Neuroimmunology, SUNY Downstate and Maimonides Medical Center researchers described the use of the calpain inhibitor for the treatment of a mouse model of MS. Whether administered by injection or by mouth, the inhibitor produced an almost complete cessation of the disease's progress.

The calpain inhibitor, developed at Downstate, was shown to reduce clinical illness signs and prevent demyelination and inflammatory infiltration in a dose- and time-dependant manner, and holds promise in treating both the acute and chronic phases of MS. The inhibitor may also prove beneficial for treating other degenerative illnesses, such as Alzheimer's, Huntington's and Parkinson's disease.

Source-Eurekalert
'"/>




Page: 1

Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers trick Alzheimers Enzyme
4. Researchers find new HIV hiding place
5. New Hair in 15 Days Could Now Be A Possibility Say Researchers
6. Researchers developed world’s smallest toothbrus
7. Researchers discover receptor cells that can cause epilepsy
8. 15 Anti-SARS Drugs Identified By China-Europe Team of Researchers
9. Researchers reversed the process of memory loss
10. Researchers Identify Key Gene That May Help Brain Treatment
11. Researchers Discover Protein That Causes Malaria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/2/2016)... ... May 02, 2016 , ... Pets bring laughter, joy and ... appreciation, pet owners celebrate National Pet Week, which falls on the first full week ... owners to cherish the human-animal bond and recognize responsible pet ownership. Pet owners can ...
(Date:5/2/2016)... ... May 02, 2016 , ... The Civilian Corps of the U.S. Army Medical ... that care for its uniformed service members, the retired service members, their families and ... 6th through May 12th National Nurses Week. It acknowledges the hard work and dedication ...
(Date:5/2/2016)... ... May 02, 2016 , ... ... help consumers better understand life insurance throughout various life stages. , The site ... life insurance needs calculator and content specific to the times when life insurance ...
(Date:5/2/2016)... ... May 02, 2016 , ... In honor of National Physical ... incentive to people who share their fitness journey on social media. , The ... products, will award a $100 product voucher each week during May to one winner. ...
(Date:5/2/2016)... ... , ... WestHarbor Growth Partners, a growth, expansion and turnaround ... Healthy Vending’s newly revamped brand campaign. Grow Healthy Vending is headquartered in ... North America with locations across the United States as well as internationally. ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... 2016  In the next ten years, the ... systems dependent on CRTs monitors to those reliant on ... Medical monitors and will automatically sync to existing ... foreseeable benefits to this technological advancement, it also ... to be replaced in order to be LCD ...
(Date:4/29/2016)... Glycotope GmbH, a clinical-stage immuno-oncology company built ... Dr. Alfredo Zurlo as Chief Medical Officer. ... years clinical experience and a proven track record in ... at Mologen AG where he was Chief Medical Officer ... held various positions at F Hoffmann La Roche and ...
(Date:4/28/2016)... 2016 Research and Markets has ... Products Market 2016-2020" report to their offering. ... The global plastic surgery products market is expected ... period 2016-2020. , ,The growing adoption of laser in ... of the market. Lasers are used to treat a ...
Breaking Medicine Technology: