Navigation Links
Domino Transplants Creates new wave In the Field Of Kidney Transplantation

According to Robert A. Montgomery, M.D., chief of transplantation at the Johns Hopkins University School of Medicine domino transplants can increase the usefulness of selfless kidney donors.//

Domino transplants strategy if used widely can also be able to solve the problem of scarcity in organ donation and reduce the waiting list. The results of the study are published in the British journal Lancet. Domino transplants also serve the needs of multiple recipients. Under the terms of the domino-paired donation program, a kidney transplant patient who has a willing but incompatible living organ donor is matched with an altruistic, compatible donor. The incompatible kidney from the recipient's intended donor is then domino-matched with the next compatible patient on the United Network of Organ Sharing (UNOS) waiting list. This strategy can be further used to enable a triple transplant by simply adding an additional incompatible donor-recipient pair to the chain.

However, because there is currently no national system of this kind in place, Montgomery says altruistic donor kidneys often end up on an Internet donation site or at individual transplant centers and so are subject to variable ethical criteria. For example, in some cases, the kidney goes to the patient deemed to have the best chance for long-term survival; in others, the organ is given to the patient in greatest need or the candidate at the top of the UNOS waiting list, regardless of outcome or need. ‘With domino-paired donation, all three of these ethical tenets are satisfied,’ says Montgomery. Specifically, the likelihood of a good outcome is increased by spreading the risk of recipient graft loss across more people.

The neediest patients are served, since in many cases patients with incompatible donors suffer disproportionately long waiting times. Those on the UNOS waiting list also benefit by receiving the last kidney in the chain. To date, Hopkins surgeons have performed t wo triple and one double domino-paired kidney transplant initiated by three altruistic donors who were able to provide eight recipients with compatible kidneys. According to Montgomery, if conventional allocation strategies had been used, only three of these recipients would have benefited from these altruistic donations. UNOS reports that since the first altruistic donor came forward in 1998, 302 altruistic kidney transplants have been performed in the United States. Using a computer simulation program, Montgomery and his team calculated that 583 transplants could have been achieved if the domino-donation model had been in place.

Altruistic donor programs have come under recent attack by critics who argue that altruistic donors may be vulnerable to coercion and have suspect motivations. Montgomery says altruistic donors go through the same rigorous and comprehensive psychological and social evaluation programs as any other person coming forward to be evaluated for living organ donation. ‘In light of the crisis the transplant community continues to experience in terms of the number of available organs,’ Montgomery says, ‘the fact that people are coming forward voluntarily to help ease this shortage should not be treated with suspicion but rather should be considered morally praiseworthy. These are good people doing good things.’

Source: Eurekaert
'"/>




Related medicine news :

1. Stem Cell Transplants May Be Effective For MS Patients
2. Kidney Failure after Non-Kidney Transplants
3. Transplants Help Liver Cancer Patients
4. Steroid-Free Liver Transplants
5. Umbilical Cord Blood Offers Hope For Patients Who Require Bone Marrow Transplants
6. Rejection Rate for Liver Transplants Patient Reduced
7. The Use Of Steroids After Liver Transplants Questioned
8. Strategies To Boost Living Donor Kidney Transplants
9. Face Transplants To Commence In The UK
10. Double Kidney Transplants to Solve Organ Donor Shortage
11. Neurological Damage Can Be Reduced By Stem Cell Transplants
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a leading Health ... technology. Applying the Purzorb™process to full spectrum CBD oil will revolutionize the rapidly growing ... form that can be easily incorporated into liquid products, while reducing costs to end ...
(Date:10/13/2017)... ... ... The Visiting Nurse Association (VNA) of Somerset Hills is proud to host ... items from across the nation, this holiday-themed event will raise funds and awareness for ... The boutique will be open Saturday, November 4 (10:00 a.m. – 5:00 p.m.) ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Agile Software Development, has been awarded a contract by the Center for Medicare ... (BPA) aims to accelerate the enterprise use of Agile methodologies in a consistent ...
(Date:10/12/2017)... LA (PRWEB) , ... October 12, 2017 , ... Planet ... in the U.S., announced today its plans to open a flagship location in Covington, ... occupy the former Rooms To Go store next to Office Depot in the Holiday ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information about the technology: ... develop to enable prevention of a major side effect of chemotherapy in children. ... pediatric patients. For cisplatin, hearing loss is FDA listed on-label as a dose ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)...  AllianceRx Walgreens Prime, the combined central specialty pharmacy ... benefit manager Prime Therapeutics LLC (Prime), today officially began ... unveiling of new signage at its headquarters in ... a few other company-owned facilities across the country. This ... of whom will begin to see the AllianceRx Walgreens ...
(Date:9/28/2017)... Cohen Veterans Bioscience and Early Signal Foundation announce a ... sensors for real-time monitoring of patients with trauma-related and ... focused on disruptive health solutions for rare disorders and ... record and integrate behavioral, cognitive, physiological and contextual data. ... ...
(Date:9/25/2017)... , Sept. 25, 2017  EpiVax, Inc., a ... design, and immune-engineering today announced the launch of ... development of personalized therapeutic cancer vaccines. EpiVax has ... exclusive access to enabling technologies to the new ... will lead EpiVax Oncology as Chief Executive Officer. ...
Breaking Medicine Technology: