Navigation Links
Digestive acid production dependent on newly found hormone

A newly discovered hormone has been found to play an important role in the digestion of fat, cholesterol, and fat-soluble vitamins, such as vitamins A, E, and D. The hormone is found to control the production of bile acid by sending signals to the liver//.

The bile acids play a very important role in the emulsification of fats that enables absorption. The hormone is called fibroblast growth factor (FGF 15), the secretion of which depends on the level of bile acid secretion. FGF15 in turn limits further production of bile acid by the liver by negative feedback mechanism.

Bile acids are powerful detergents; the concentrations must be tightly regulated for proper functioning of the human body. The body needs enough quantity of the bile acid to absorb fat and other nutrients. However, too much can damage tissues and organs. This new mechanism probably holds the key to protect the body from the effects of over production of the bile acid.

Researchers have identified a receptor that senses bile acid and responds by secreting FGF15. In the liver, the secreted intestinal protein limits the activity of an enzyme called cholesterol 7a-hydroxylase (CYP7A1) critical to bile acid production. Animal models lacking FGF15 were found to have increased CYP7A1 activity and excrete greater quantities of bile acid.

The results of the present study have valuable clinical implications. For example, the above mentioned feedback mechanism might be an explanation to the liver damage associated with intravenous infusion of nutrients.

The findings also raise additional questions about the role that the circulating hormone may play in other parts of the body. An additional insight into cholesterol-derived bile acids might also yield important clues regarding cholesterol control. However, further studies in human beings are needed at the moment.
'"/>




Page: 1

Related medicine news :

1. Breast-fed Children Weather Digestive Disease
2. Obesity: Digestive Disorders Come In The Way Of Exercise
3. Silence Puts Comfort For Digestive Syndrome
4. Many Irish in the Grips of Digestive Disorders
5. Bioengineering production strains - Microbia develops new methods
6. Roche confirms Tamiflu production talks in US
7. Pigs have another utility: production of healthy oils!
8. WHO takes initiative to fight corruption tainted medicine production-supply chain
9. Adult bone health is dependent on lifestyle we live
10. Religious sensitivity of medicos gender-dependent
11. Time for Bono to Rock The Independent For AIDS Awareness
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/12/2017)... ... October 12, 2017 , ... Information about the technology: , ... to enable prevention of a major side effect of chemotherapy in children. Cisplatin ... patients. For cisplatin, hearing loss is FDA listed on-label as a dose limiting ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a ... of a 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners ... October 11, 2017. , The annual award competition recognizes editorial and design excellence across ...
(Date:10/12/2017)... ... October 12, 2017 , ... On Saturday, October 21, the Health & ... by Moonlight to raise money for the American Heart Association Heart Walk. Teams of ... will work together to keep their treadmills moving for 5 hours. Treadmills will start ...
(Date:10/12/2017)... ... , ... Health Literacy Innovations (HLI), creator of the Health ... Cancer Patient Education Network (CPEN), an independent professional organization that shares best practices ... , As CPEN’s strategic partner, HLI will help support CPEN members by ...
(Date:10/12/2017)... ... 12, 2017 , ... Vohra Chief Medical Officer Dr. Shark ... skilled nursing facility medical directors and other clinicians at various events in October. ... "At many of these conferences we get to educate other physicians, facility nurses, ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... , Oct. 11, 2017  Hill-Rom Holdings, Inc. ... Aspen Surgical facility in Las Piedras, Puerto ... scalpels and blades. ... that the facility sustained minor structural damage, temporary loss ... Maria. Repairs have been completed, manufacturing operations have resumed, ...
(Date:10/5/2017)... ROSEMONT, Ill. , Oct. 5, 2017 /PRNewswire-USNewswire/ ... American Association of Oral and Maxillofacial Surgeons (AAOMS) ... than opioids – to be used as a ... post-surgical pain. ... relationship, the AAOMS White Paper "Opioid Prescribing: Acute ...
(Date:10/2/2017)... , Oct. 2, 2017 Diplomat Pharmacy, Inc. ... Day Software and Consulting, LLC , and named its ... Software, based in Tennessee , will ... Day expands EnvoyHealth,s service offerings for health care partners ... "In an interoperable world, ...
Breaking Medicine Technology: