Navigation Links
Digestive acid production dependent on newly found hormone

A newly discovered hormone has been found to play an important role in the digestion of fat, cholesterol, and fat-soluble vitamins, such as vitamins A, E, and D. The hormone is found to control the production of bile acid by sending signals to the liver//.

The bile acids play a very important role in the emulsification of fats that enables absorption. The hormone is called fibroblast growth factor (FGF 15), the secretion of which depends on the level of bile acid secretion. FGF15 in turn limits further production of bile acid by the liver by negative feedback mechanism.

Bile acids are powerful detergents; the concentrations must be tightly regulated for proper functioning of the human body. The body needs enough quantity of the bile acid to absorb fat and other nutrients. However, too much can damage tissues and organs. This new mechanism probably holds the key to protect the body from the effects of over production of the bile acid.

Researchers have identified a receptor that senses bile acid and responds by secreting FGF15. In the liver, the secreted intestinal protein limits the activity of an enzyme called cholesterol 7a-hydroxylase (CYP7A1) critical to bile acid production. Animal models lacking FGF15 were found to have increased CYP7A1 activity and excrete greater quantities of bile acid.

The results of the present study have valuable clinical implications. For example, the above mentioned feedback mechanism might be an explanation to the liver damage associated with intravenous infusion of nutrients.

The findings also raise additional questions about the role that the circulating hormone may play in other parts of the body. An additional insight into cholesterol-derived bile acids might also yield important clues regarding cholesterol control. However, further studies in human beings are needed at the moment.
'"/>




Page: 1

Related medicine news :

1. Breast-fed Children Weather Digestive Disease
2. Obesity: Digestive Disorders Come In The Way Of Exercise
3. Silence Puts Comfort For Digestive Syndrome
4. Many Irish in the Grips of Digestive Disorders
5. Bioengineering production strains - Microbia develops new methods
6. Roche confirms Tamiflu production talks in US
7. Pigs have another utility: production of healthy oils!
8. WHO takes initiative to fight corruption tainted medicine production-supply chain
9. Adult bone health is dependent on lifestyle we live
10. Religious sensitivity of medicos gender-dependent
11. Time for Bono to Rock The Independent For AIDS Awareness
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/26/2017)... BC (PRWEB) , ... July 26, 2017 , ... ... (the “Company” or “Isodiol”) a global cannabis innovator, specializing in the development of ... the period from April 1, 2017 to June 30, 2017. Iso International LLC ...
(Date:7/26/2017)... ... 26, 2017 , ... The number of adults 65 years or older is ... improve asthma control in the population are not well described. In a study published ... official journal of the American Academy of Allergy, Asthma & Immunology (AAAAI), researchers identified ...
(Date:7/25/2017)... ... July 25, 2017 , ... Creative Pharmacist and ... provide the Pharmacist eCare Plan to Computer-Rx pharmacies through the STRAND ... ability to develop the Pharmacist eCare Plan, a shared document detailing a patient’s ...
(Date:7/25/2017)... ... July 25, 2017 , ... Nautilus Hyosung ... States, today announced its partnership with financial technology company, Automated Transaction Delivery (ATD), ... the solution lies within Hyosung’s superior ATMs, assisted self-service devices and associated software. ...
(Date:7/25/2017)... ... 2017 , ... SignatureCare Emergency Center – South Austin is treating both adult ... day. , The Emergency Room opened early March, making it the ... now and things are running smoothly,” said Aaron Braun, SignatureCare Emergency Center’s Chief Medical ...
Breaking Medicine News(10 mins):
(Date:7/14/2017)... International plc (NASDAQ: ENDP ) will announce its second-quarter ... senior management team will host a conference call and webcast before ... The dial-in number to access the call is U.S./ ... is 45397076. Please dial in 10 minutes prior to the scheduled ... of the call will be available from August 8, 2017 at ...
(Date:7/12/2017)... -- CarpalAID is a revolutionary new product that relieves painful carpal ... tunnel syndrome affects more than 8 million people a year. Women ... The common methods of treating CTS are painful surgery, the use ... gloves. ... CarpalAID is a clear patch worn on the palm of the ...
(Date:7/11/2017)... 11, 2017  Sysmex America, Inc., a leading ... equipment as well as middleware information systems technology, ... make quality assurance easier and more risk free ... known for the innovation that it delivers to ... quality assurance processes to a new level with ...
Breaking Medicine Technology: