Navigation Links
Digestive acid production dependent on newly found hormone

A newly discovered hormone has been found to play an important role in the digestion of fat, cholesterol, and fat-soluble vitamins, such as vitamins A, E, and D. The hormone is found to control the production of bile acid by sending signals to the liver//.

The bile acids play a very important role in the emulsification of fats that enables absorption. The hormone is called fibroblast growth factor (FGF 15), the secretion of which depends on the level of bile acid secretion. FGF15 in turn limits further production of bile acid by the liver by negative feedback mechanism.

Bile acids are powerful detergents; the concentrations must be tightly regulated for proper functioning of the human body. The body needs enough quantity of the bile acid to absorb fat and other nutrients. However, too much can damage tissues and organs. This new mechanism probably holds the key to protect the body from the effects of over production of the bile acid.

Researchers have identified a receptor that senses bile acid and responds by secreting FGF15. In the liver, the secreted intestinal protein limits the activity of an enzyme called cholesterol 7a-hydroxylase (CYP7A1) critical to bile acid production. Animal models lacking FGF15 were found to have increased CYP7A1 activity and excrete greater quantities of bile acid.

The results of the present study have valuable clinical implications. For example, the above mentioned feedback mechanism might be an explanation to the liver damage associated with intravenous infusion of nutrients.

The findings also raise additional questions about the role that the circulating hormone may play in other parts of the body. An additional insight into cholesterol-derived bile acids might also yield important clues regarding cholesterol control. However, further studies in human beings are needed at the moment.
'"/>




Page: 1

Related medicine news :

1. Breast-fed Children Weather Digestive Disease
2. Obesity: Digestive Disorders Come In The Way Of Exercise
3. Silence Puts Comfort For Digestive Syndrome
4. Many Irish in the Grips of Digestive Disorders
5. Bioengineering production strains - Microbia develops new methods
6. Roche confirms Tamiflu production talks in US
7. Pigs have another utility: production of healthy oils!
8. WHO takes initiative to fight corruption tainted medicine production-supply chain
9. Adult bone health is dependent on lifestyle we live
10. Religious sensitivity of medicos gender-dependent
11. Time for Bono to Rock The Independent For AIDS Awareness
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating ... many ways they remain in the eye of the beholder, according to experts who ... of The American Journal of Managed Care. For the full issue, click here ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements ... was developed to enhance the health of felines. The formula is all-natural and is ... herbs in the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus ...
(Date:6/25/2016)... D.C. (PRWEB) , ... June 25, 2016 , ... ... discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, ... their work on several important health care topics including advance care planning, healthcare ...
(Date:6/25/2016)... ... 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users can easily ... of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures ... . Simply select a ProHand generator and drag it above media or text in ...
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016   Bay ... Rehabilitation Network,s Dean Center for Tick Borne ... Medicine and Rehabilitation, MIT Hacking Medicine, University of ... Innovation, today announced the five finalists of ... Lyme disease.  More than 100 scientists, clinicians, researchers, ...
(Date:6/24/2016)... , June 24, 2016 ... the "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural ... Structural electronics involves electronic and/or ... protective structures, replacing dumb structures such as vehicle ...
(Date:6/24/2016)... , June 24, 2016 Dehaier Medical Systems ... "Company"), which develops, markets and sells medical devices and ... , signed a strategic cooperation agreement with Hongyuan Supply ... Supply Chain") on June 20, 2016, to develop Dehaier,s ... strategic cooperation agreement, Dehaier will leverage Hongyuan Supply Chain,s ...
Breaking Medicine Technology: