Navigation Links
Different Treatments Needed For Breathing Problems

Researchers have identified a particular gene that influences how severe a M. pneumoniae infection may be, which in turn suggests that a different strategy// might be needed for treating asthma resulting from this and similar lung infections rather than allergies.

"What this shows is that infectious asthma might have a different mechanism than allergic asthma. Most people think asthma is asthma, but it may be multifaceted," said Dr. Robert Hardy, an infectious disease specialist at UT Southwestern.

That's an important implication because the latest statistics show that asthma is on the rise. According to the U.S. Centers for Disease Control, more than 20 million Americans currently have asthma and another 10 million have been diagnosed with asthma at some point in their life. Roughly 6.5 million American children, or nearly 9 percent of the nation's pre-adult population, have asthma, figures released in December show.

Dr. Hardy, an assistant professor of internal medicine and pediatrics, has been using mice to study how certain pneumonia bacteria contribute to chronic asthma and, in this latest study, identified how a particular gene may contribute to more severe lung infection. The research appears in the January edition of Infection and Immunity.

Pneumonia is a lung infection typically characterized by breathing difficulties and spread by coughing and sneezing. Symptoms often include headache, fever, chills, coughs, chest pains, sore throat and nausea. Dr. Hardy's research involves pneumonia caused by the bacterium M. pneumoniae, commonly called walking pneumonia, a typically less severe form of the disease that accounts for 20 percent to 30 percent of community-acquired pneumonia.

To investigate the mechanism by which M. pneumoniae causes lung disease and respiratory difficulties, the UT Southwestern researchers inoculated two different types of mice with this bacterium. The study contrasted the re action of one normal group of mice with another group lacking a particular gene called IL-12, which is involved in immune response. The mice engineered without the gene showed significantly less lung inflammation than the mice that naturally had the gene, with some indicators showing seven times less inflammation.

"M. pneumoniae might be more of a cofactor in developing chronic asthma than a direct cause, similar to how high cholesterol or diabetes makes people more vulnerable to heart attacks," Dr. Hardy said, pointing to a number of previous studies. "It's probably not the only thing, but it's one of them. In some people it might incite asthma or it might exacerbate it."

Because the M. pneumoniae bacterium is difficult to kill and often remains in the lungs even after antibiotic treatment and the symptoms fade, Dr. Hardy said, it is important to find better treatments to prevent it from lingering.

Source-Eurekalert
SRI
'"/>




Related medicine news :

1. Different Sun Rays, Different Damage
2. Heart Attack Symptoms Different in Women
3. The Cause Of Visual Problems Different From Race To Race
4. Different Drug May Help Children With Duchenne Muscular Dystrophy
5. Learning Just How Different We Are
6. Different Types Of Multiple Sclerosis May Be Treated Differently
7. Have You Ever Wondered How We Perceive Different Sounds?
8. Resident Physicians Need More Preparations To Treat Patients From Different Cultures
9. Differentiated Thyroid Carcinoma Can Widely Infiltrate The Larynx
10. Men Use Their Brain Differently From Women
11. Alcohol Is Responsible For 60 Different Diseases
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2016)... ... April 28, 2016 , ... ... the open availability of a new CDISC standard, Clinical Trial Registry (CTR) ... trials. This innovative standard will make it possible to build applications that ...
(Date:4/28/2016)... ... April 28, 2016 , ... Trinity Health, one ... a leading force in the fight to reduce tobacco use and its deadly ... can help reduce tobacco use. The initiative brings together two organizations committed to ...
(Date:4/28/2016)... ... April 28, 2016 , ... In 2011, TIME magazine named Herr the “Leader ... biomechatronics, technology that marries human physiology with electromechanics. He continues that work as Director ... Founder of BionX , a leader in the field of prosthetic devices. , ...
(Date:4/28/2016)... ... April 28, 2016 , ... Cognizin® Citicoline is one of ... in the Healthy Ageing category, Cognizin® is being considered for this prestigious honor ... can include everything from antioxidants, lipids, proteins, and botanicals. NutraIngredients will choose a ...
(Date:4/28/2016)... ... ... Card reminds us that May is National Stroke Awareness Month. According to the Centers ... in the United States; someone has one every 40 seconds. Annually, almost 800,000 strokes ... old. A stroke is when blood flow to the brain is blocked or when ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... April 27, 2016 Shire plc (LSE: ... Poulton , Chief Financial Officer, will present at the Deutsche ... MA on Wednesday, May 04, 2016, 10:00 am ... be available on the Presentations and Webcasts section of Shire,s ... the webcast will be available on this same website for ...
(Date:4/27/2016)... 27, 2016 Oasmia Pharmaceutical ... of a new generation of drugs within human ... results for Paclical/Apealea in the Phase III study ... epithelial ovarian cancer. These preliminary results showed non-inferiority ... with carboplatin versus Taxol in combination with carboplatin. ...
(Date:4/27/2016)... , April 27, 2016 ... reach USD 2.06 billion by 2022, according to ... Increasing consumer awareness towards a healthy lifestyle is ... seven years.      (Logo: http://photos.prnewswire.com/prnh/20150105/723757 ... coupled with rising health treatment expenditure has urged ...
Breaking Medicine Technology: