nt to 54 percent in three consecutive five-year periods during a study of 4,596 patients who were discharged with a heart failure diagnosis at the two Mayo Clinic hospitals in Olmsted County, Minn., from 1987 through 2001. Among heart failure patients, the prevalence of diseases that cause diastolic heart failure and worsen its symptoms -- including hypertension, atrial fibrillation and diabetes -- also increased over the study period. The increase in the proportion of diastolic heart failure was due to increases in the number of diastolic heart failure cases with no change in the number of systolic heart failure cases.
On average, mortality rates for the two forms of heart failure were very similar. Importantly, while improvements in survival rates over the study period were seen for systolic heart failure, no such improvement was observed for diastolic heart failure, Dr. Redfield says. ‘There are a number of likely reasons why patients with systolic heart failure are doing better,’ she says. ‘Research has helped us discover many therapies for systolic heart failure -- drugs, devices and surgical procedures -- to counteract the mechanisms that cause or worsen systolic heart failure, and we've seen the proven benefit of those therapies in large scale clinical trials. This approach now needs to be expanded to the other half of the heart failure epidemic, patients with diastolic heart failure.’
Source: Eurealert
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