Navigation Links
Diarrhea Vaccine Trials Promises Prevention of Rotavirus Infection

Vaccine trials conducted on Rotateq and Rotarix in more than 1, 30, 000 children offer promise in the prevention of childhood diarrhea. The vaccines have been found to be 98% and 85% effective respectively. // The dreadful disease accounts for 1/3rd of all hospital infections worldwide.

A vaccine had been developed for the disease during the 1990’s. This however, was withdrawn from the market owing to the possibility of a potential life-threatening condition, referred to as intussusception. This condition is characterized by intestinal folding, followed by intestinal blockage.

Almost all children suffer from rotavirus infection, at age 2 or 3. The most signs of infection include vomiting, fever, pain in the abdomen, watery diarrhea that can be fatal. Asymptomatic presentation can also be seen in a small proportion of the cases.

The incidence of rotavirus infection is estimated to be 1 in 38 in the UK. The incidence is even higher in the developing and underdeveloped countries. This can be attributed to poor sanitation and the lack of proper health care access.

Merck, a leading pharmaceutical company, has developed the vaccine, Rotateq. The vaccine can effectively manage five major strains of the rotavirus, believed to be associated with 90% of the infections. The study participants were divided into two groups; one group received the vaccine while the other group received a placebo. The study participants were closely monitored for the presence of adverse effects. A comparative revealed that there was no increased risk of side effects in the vaccine group.

Rotarix, an oral vaccine has been developed by GlaxoSmithKline and clinical trials were conducted to analyze the safety and efficacy of the formulation in over 63,000 infants. The study further documented a significant reduction in the hospital admissions related to rotavirus infection. No difference was seen in the complication rate as well.

"As vaccines become licensed and used in the US and Europe, we should expect to see a substantial reduction in winter hospitalizations, visits to doctors and clinics and parents' workdays lost to childhood diarrhea", said Dr Roger Glass and Dr Umesh Parashar, from the US Centers for Disease Control.

"Both vaccines will need to demonstrate their efficacy in the difficult settings of developing countries if we are to achieve our goal of maximally decreasing global deaths from diarrhea”, they concluded.


Related medicine news :

1. Pakistani Quake Survivors Face Outbreak Of Diarrhea
2. Health Minister Inaugurates Institute for Diarrhea Diseases
3. A New Drug Promises To Be Very Effective In The Management Of Diarrhea
4. Two Die, 55 Afflicted With Gastroenteritis And Diarrhea
5. Mothers in African Study Undereducated on Diarrhea
6. GM Rice to Tackle Diarrhea
7. Vaccine to quit smoking?
8. First Vaccine Designed for Africa Cleared for Testing in Humans
9. Vaccine for Alzheimer’s diseas
10. Health Officials Recommend Flu Vaccine
11. Smallpox Vaccine May Help Fight Cervical Cancer
Post Your Comments:

(Date:6/27/2016)... ... 27, 2016 , ... "FCPX editors can now reveal their media with growing ... said Christina Austin - CEO of Pixel Film Studios. , ProSlice Color brings ... users can now reveal the media of their split screens with growing colorful panels. ...
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer care, ... remain in the eye of the beholder, according to experts who offered insights and ... Journal of Managed Care. For the full issue, click here . , For ...
(Date:6/26/2016)... ... June 26, 2016 , ... Many women are confused ... endometriosis. These women need a treatment plan to not only alleviate symptoms and ... help for preservation of fertility and ultimately achieving a pregnancy. The specialists at ...
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... ... the United States, named Dr. Sesan Ogunleye, as the Medical Director of its new ... the facility Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, ...
(Date:6/24/2016)... ... 24, 2016 , ... A recent article published June 14 on ... article goes on to state that individuals are now more comfortable seeking to undergo ... such as calf and cheek reduction. The Los Angeles area medical group, Beverly Hills ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... The Academy of Managed Care Pharmacy (AMCP) ... would allow biopharmaceutical companies to more easily share health ... and coverage decisions, a move that addresses the growing ... The recommendations address restrictions in the sharing of ... label, a prohibition that hinders decision makers from accessing ...
(Date:6/24/2016)... India , June 24, 2016 ... Needles Market by Type (Standard Pen Needles, Safety Pen ... Therapy (Insulin, GLP-1, Growth Hormone), Mode of Purchase (Retail, ... by MarketsandMarkets, This report studies the market for the ... expected to reach USD 2.81 Billion by 2021 from ...
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
Breaking Medicine Technology: