( ur understanding of diabetes and our ab...)Diabetes on the Rise among Filipinos,Health

ur understanding of diabetes and our ability to treat it effectively. Clearly the best way to prevent the serious health consequence of diabetes is to prevent it from occurring.”

A GSK study called the DREAM trial (or Diabetes Reduction Approaches with ramipril and rosiglitazone Medications) for pre-diabetes patients showed the risk of developing Type 2 Diabetes was reduced by 62 percent, compared to placebo among people at high risk of developing the said disease.

The results of the study, which involved the largest diabetes-prevention study of 5,269 respondents, were presented at the 42nd annual meeting of the European Association for the Study of Diabetes (EASD) in Copenhagen.

According to the study, over the three-year median follow-up period, 51 percent of those who received rosiglitazone returned to normal blood sugar levels compared to 30 percent of those who received placebo. Rosiglitazone maleate is the active component of Avandia, a product developed by GlaxoSmithKline, a global research-based pharmaceutical company.

The study was designed and conducted by the Population Health Research Institute at McMaster University, which indicates that 10.6 percent of those who received rosiglitazone progressed to Type 2 Diabetes compared to 25 percent of people treated with placebo. In the composite primary endpoint of development of diabetes or death from any cause, rosiglitazone demonstrated a 60-percent risk reduction relative to placebo.

Rosiglitazone belongs to the thiazolidinedione class of drugs. It provides long-term sugar control and is an approved treatment for Type 2 diabetes. So far no other drug has been approved for pre-diabetes treatment.



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