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Diabetes Risk Factors Develop Earlier in Women Than Men

sease. They received a physical examination when they entered the study and again for this six-year follow-up.

Standard measures - height, weight, waist girth, blood pressure - were taken, plus blood samples to determine concentrations of fasting glucose and insulin, specific proinflammatory markers, C-reactive protein and markers of dysfunction in the endothelial tissue, the tissue lining blood vessels.

Results showed that 52 women and 39 men had progressed from normal blood glucose levels to pre-diabetic status during the previous six years.

Donahue said the question of what explains the sex difference remains to be determined, and he plans to study this in the future. He suggested that women whose blood glucose increases over time, even if it doesn't reach diabetic levels, should be screened more intensively for cardiovascular disease.

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