Navigation Links
Diabetes Drug Dramatically Boosts Potency of Platinum Chemotherapy

erapy -- and proved capable of reducing growth of the cancer cells by 90 percent. Even when applied to colon cancer cells, a type of cancer not usually treated with platinum drugs, rosiglitazone and carboplatin lowered the growth rate by 70 percent. (Rosizitaglone did not show the same positive effect when paired with oxalyplatin.)

The drug combination also had striking growth-suppressing results when given to mice with human lung and ovarian tumors implanted under their skin and in mice that had received a chemical that causes them to develop colon cancer, explained Spiegelman, who is also a professor of cell biology at Harvard Medical School.

The experiments showed that the PPAR-gamma ligands suppressed the activity of metallothioneine genes, which are believed to trigger the development of cancer cells resistance to platinum chemotherapy.

"Our finding that PPAR-gamma activation dramatically increases the efficacy of carboplatin, potentially causing tumor stasis or even tumor shrinkage could represent a significant advance in chemotherapy," the researchers wrote.


'"/>




Page: 1 2 3

Related medicine news :

1. Is Diabetes the Leading Cause of Kidney Failure in India
2. Diabetes and Depression often go hand-in-hand
3. Thirty minutes of work up per day reduces the risk of Diabetes
4. Diabetes on the rise
5. Irregular Periods Linked to Diabetes
6. Cinnamon combats Diabetes
7. Good News For Women With Gestational Diabetes
8. Processed Meat, Diabetes connection Found
9. Pancreatic Cancer may be linked to Diabetes
10. Gestational Diabetes linked to Chromosomal defici
11. A way to slow the progression of Type 1 Diabetes
Post Your Comments:
(Date:9/22/2014)... 2014 One key emerging trend in ... investing in R&D to develop new and advanced biomaterial ... implants. The introduction of third-generation orthopedic biomaterials such as ... will increase the growth of the market in the ... market to grow at a CAGR of 10.78 ...
(Date:9/22/2014)... (PRWEB) September 22, 2014 AttorneyOne.com, a recognized ... latest information from the FDA on Twix . , ... Twix Unwrapped Bites 7 oz. Stand Up Pouch with specific ... for the recall is that Twix Unwrapped Bites ... contain peanuts and eggs without writing them on the ingredient ...
(Date:9/22/2014)... In CHAMPS Patient Experience's most recent blog ... Summer Meeting , Toya Gorley shares her thoughts on ... The Leader’s Board meeting this summer, which was comprised ... experience to be exhilarating! Many topics were discussed, including:, ... on the patient experience , Technology ...
(Date:9/22/2014)... September 22, 2014 Fancyflyingfox.com, the well-known wedding ... of 2014 plus size wedding dresses . In addition, ... for these fashionable plus size outfits. Each item in the ... up to 65% off. , The company has thousands ... them are now available at extremely affordable prices. Its products ...
(Date:9/21/2014)... cancer patients who smoke, those using e-cigarettes (in addition ... or less likely to have quit smoking traditional cigarettes ... a peer-reviewed journal of the American Cancer Society, the ... for helping cancer patients give up smoking. , Because ... who smoke should be advised to quit. But the ...
Breaking Medicine News(10 mins):Health News:Orthopedic Biomaterials Market to Grow at 10.78% CAGR by 2018, Forecasts a New Research Report at ReportsnReports.com 2Health News:Orthopedic Biomaterials Market to Grow at 10.78% CAGR by 2018, Forecasts a New Research Report at ReportsnReports.com 3Health News:Orthopedic Biomaterials Market to Grow at 10.78% CAGR by 2018, Forecasts a New Research Report at ReportsnReports.com 4Health News:Mars Chocolate North America Recalls Twix Bites: AttorneyOne Monitors and Keeps Consumers Informed 2Health News:CHAMPS' Toya Gorley Discusses the Thought-Provoking Conversation at The Leader’s Board Summer Meeting 2Health News:Discounted Plus Size Wedding Dresses Available At Fancyflyingfox.com 2Health News:E-cigarettes unhelpful in smoking cessation among cancer patients 2
... a changed version of dopamine// transporter in healthy ... with substance abuse or attention deficit hyperactivity disorder ... the hypothalamus and some areas of the central ... play an important role in hormonal, cardiovascular, renal ...
... is possible to increase the heights of children who ... improved dosages of the growth hormones. ,The researchers ... that the administration of the growth hormone GH-dependent hormone ... (IGF-I) can affect the growth of children in height. ...
... have found out new information about how neuro ... be possibly slowed. ,Researchers at the Rocky ... found novel insights into how abnormal prion proteins ... mice producing prion protein without a glycophosphoinositol (GPI) ...
... be used to detect cancer, says a new study that ... and son research team had been able to bind the ... that will make the tracing of cancer cells much easier. ... factor receptor (EFGR) over their surface. This protein is not ...
... be at less risk from colorectal// cancer. And women who ... B may have even reduced chance of having colorectal cancer. ... of abnormal or malignant cells within the lining of colon ... American researchers, said that inadequate intake of dietary vitamin B ...
... problems// like cognitive impairment in children. ,Researchers across the ... of pollutants like noise from the traffic and aircrafts on ... of 2844 children in the age group of 9 to ... Netherlands, Spain, and UK. Researchers had taken the help of ...
Cached Medicine News:
(Date:9/19/2014)... , Sept. 19, 2014 /PRNewswire-iReach/ -- Market ... Hydrochloride Industry, 2009-2019 is a professional and ... Oxybutynin Hydrochloride industry. The report firstly reviews ... its classification, application and manufacturing technology. The ... manufacturers of Oxybutynin Hydrochloride listing their product ...
(Date:9/19/2014)... CHICAGO, Ill. , Sept. 19, 2014  The ... ABBV ) declared a quarterly cash dividend of $0.42 ... payable Nov. 17, 2014 to stockholders of record at ... About AbbVie AbbVie is a global, research-based biopharmaceutical ... company,s mission is to use its expertise, dedicated people ...
(Date:9/19/2014)... -- Merck (NYSE: MRK ), known as MSD outside ... , is teaming with celebrity chef and cookbook author Leticia ... an educational program encouraging Hispanics with type 2 diabetes to achieve ... to help reduce the risk of serious health problems. Hispanics in ... risk for developing type 2 diabetes than non-Hispanic white adults, and ...
Breaking Medicine Technology:Oxybutynin Hydrochloride Industry 2014-2019 Chinese Forecasts & Analysis 2Oxybutynin Hydrochloride Industry 2014-2019 Chinese Forecasts & Analysis 3Oxybutynin Hydrochloride Industry 2014-2019 Chinese Forecasts & Analysis 4Oxybutynin Hydrochloride Industry 2014-2019 Chinese Forecasts & Analysis 5Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 2Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 3Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 4Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 5
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: