Navigation Links
Depression Increases the Risk of Disease Progression and Death in HIV-positive Women

Depression plays an important role in clinical disease progression and death in HIV-1-infected women in Sub-Saharan Africa, according to a study published// in the Journal of Acquired Immune Deficiency Syndromes. The study found that depression is common among HIV-infected Tanzanian women and recommends screening for depression and providing psychosocial interventions as part of a comprehensive HIV care.

There is increasing evidence that depression or stress may accelerate HIV disease progression. Depression might directly alter immune functions or might cause behavioral changes resulting in non-adherence to treatment regimes and a reduced food uptake.

The prevalence of psychiatric disorders among HIV-infected African women is not known. Although depression has been reported in 47% of Ugandan HIV-infected men and women and in about 30% of HIV-infected Rwandese women, there is a paucity of studies which link depression and HIV clinical disease progression in developing countries. A team of Tanzanian and US investigators has addressed this issue.

The study was nested within a randomized controlled trial of vitamin supplementation in pregnant women.

The primary end-points of the parent study included vertical transmission rates, pregnancy outcomes, HIV disease progression, and mortality among the women and their children born into the study. Nine hundred and ninety-six women with at least one depression measure taken during pregnancy or more than twelve months postpartum were eligible for the depression study. Post-partum depression was eliminated by excluding the depression data collected between delivery and twelve months postpartum.

The women were followed up monthly and later quarterly for approximately six to eight years after HIV diagnosis. Survival and mortality data were collected through tracing participants if a clinic visit was missed. A woman was classified as alive on the day of contact if a home visitor reported talking to or seeing her.

About two months after enrolment, every six months until 2001, and every twelve months thereafter, a psychosocial questionnaire was administered to assess depression /anxiety symptoms based on eight out of the 25-item scale of the Hopkins Symptoms Checklist (HSCL-25). A previous study in this population validated the usefulness of the eight point sub-scale for assessing depression. A social support scale, based on a ten-item questionnaire on emotional or affective (six) and material or instrumental (four) support, was used to assess social support among the patients.

A psychiatric nurse provided individual counseling in the clinic and facilitated a weekly peer support group for women who needed or required counseling for depressive or anxiety symptoms. Women were encouraged to visit the study clinic if they were ill or required counseling.

Depression is not only common but is an independent predictor of disease progression and death among HIV-infected African women, the authors conclude. This brings into sharp relief the urgent need for additional studies to assess the effectiveness of psychosocial interventions in preventing or delaying disease progression.

The policy implication is that, alongside antiretroviral drug treatment, management of depression and psychiatric disorders must be an integral part of the health care package provided to all HIV-infected patients.

Source-Bio-Bio Technology/M
'"/>




Related medicine news :

1. Low Cholesterol Linked to Severe Depression and Violent Behavior in Men
2. Depression may cause delayed wound healing
3. Diabetes and Depression often go hand-in-hand
4. Depression and heart failure
5. Depression disturbs heart rate
6. Depression a possible danger in elderly
7. Depression linked to mortality
8. Depression increases heart attacks
9. More People Seeking Treatment for Depression
10. Depression elevates heart failure risk
11. Depression hurts the heart
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Dickinson ... offers insurance and financial preparation services, is providing an update on a charitable ... , Rock City Rescue is a locally recognized nonprofit that provides shelter and ...
(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a leading Health ... technology. Applying the Purzorbℱprocess to full spectrum CBD oil will revolutionize the rapidly growing ... form that can be easily incorporated into liquid products, while reducing costs to end ...
(Date:10/13/2017)... , ... October 13, 2017 , ... The Visiting Nurse ... Market. Featuring a collection of specialty vendors and unique items from across the nation, ... quality-focused health and wellness services offered by the VNA. The boutique will be ...
(Date:10/13/2017)... VA (PRWEB) , ... October 13, 2017 , ... ... of DevOps and Agile Software Development, has been awarded a contract by the ... Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies ...
(Date:10/12/2017)... Orleans, LA (PRWEB) , ... October 12, 2017 , ... ... centers in the U.S., announced today its plans to open a flagship location in ... will occupy the former Rooms To Go store next to Office Depot in the ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)...  True Health, a leader in integrated diagnostics ... National Breast Cancer Awareness month to educate doctors ... Research recently published in ... than 10 million American women are at significant ... BRCA2 and have not had testing. These mutations can ...
(Date:10/7/2017)... 6, 2017   Provista, a proven leader ... billion in purchasing power, today announced a new resource ... The Newsroom is the online home for case ... expert bios, news releases, slideshows and events. ... wealth of resources at their fingertips, viewers can also ...
(Date:10/4/2017)... Mass. , Oct. 4, 2017 ... of single-use, self-contained, illuminating medical devices, today announced ... National Health Surveillance Agency (or AgĂȘncia Nacional de ... The first single-use, cordless surgical retractor with integrated ... provides optimal access, illumination and exposure of a ...
Breaking Medicine Technology: