Navigation Links
Depression Increases the Risk of Disease Progression and Death in HIV-positive Women

Depression plays an important role in clinical disease progression and death in HIV-1-infected women in Sub-Saharan Africa, according to a study published// in the Journal of Acquired Immune Deficiency Syndromes. The study found that depression is common among HIV-infected Tanzanian women and recommends screening for depression and providing psychosocial interventions as part of a comprehensive HIV care.

There is increasing evidence that depression or stress may accelerate HIV disease progression. Depression might directly alter immune functions or might cause behavioral changes resulting in non-adherence to treatment regimes and a reduced food uptake.

The prevalence of psychiatric disorders among HIV-infected African women is not known. Although depression has been reported in 47% of Ugandan HIV-infected men and women and in about 30% of HIV-infected Rwandese women, there is a paucity of studies which link depression and HIV clinical disease progression in developing countries. A team of Tanzanian and US investigators has addressed this issue.

The study was nested within a randomized controlled trial of vitamin supplementation in pregnant women.

The primary end-points of the parent study included vertical transmission rates, pregnancy outcomes, HIV disease progression, and mortality among the women and their children born into the study. Nine hundred and ninety-six women with at least one depression measure taken during pregnancy or more than twelve months postpartum were eligible for the depression study. Post-partum depression was eliminated by excluding the depression data collected between delivery and twelve months postpartum.

The women were followed up monthly and later quarterly for approximately six to eight years after HIV diagnosis. Survival and mortality data were collected through tracing participants if a clinic visit was missed. A woman was classified as alive on the day of contact if a home visitor reported talking to or seeing her.

About two months after enrolment, every six months until 2001, and every twelve months thereafter, a psychosocial questionnaire was administered to assess depression /anxiety symptoms based on eight out of the 25-item scale of the Hopkins Symptoms Checklist (HSCL-25). A previous study in this population validated the usefulness of the eight point sub-scale for assessing depression. A social support scale, based on a ten-item questionnaire on emotional or affective (six) and material or instrumental (four) support, was used to assess social support among the patients.

A psychiatric nurse provided individual counseling in the clinic and facilitated a weekly peer support group for women who needed or required counseling for depressive or anxiety symptoms. Women were encouraged to visit the study clinic if they were ill or required counseling.

Depression is not only common but is an independent predictor of disease progression and death among HIV-infected African women, the authors conclude. This brings into sharp relief the urgent need for additional studies to assess the effectiveness of psychosocial interventions in preventing or delaying disease progression.

The policy implication is that, alongside antiretroviral drug treatment, management of depression and psychiatric disorders must be an integral part of the health care package provided to all HIV-infected patients.

Source-Bio-Bio Technology/M
'"/>




Related medicine news :

1. Low Cholesterol Linked to Severe Depression and Violent Behavior in Men
2. Depression may cause delayed wound healing
3. Diabetes and Depression often go hand-in-hand
4. Depression and heart failure
5. Depression disturbs heart rate
6. Depression a possible danger in elderly
7. Depression linked to mortality
8. Depression increases heart attacks
9. More People Seeking Treatment for Depression
10. Depression elevates heart failure risk
11. Depression hurts the heart
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/24/2016)... , ... May 24, 2016 , ... How to Write ... Raleigh, NC, http://www.fdanews.com/humanerrordrugdevice , Human error is known to be the major ... human error will ever be totally eliminated, many human performance problems can be prevented. ...
(Date:5/24/2016)... ... May 24, 2016 , ... Loma Linda University Health (LLUH) has officially broken ... Children’s Hospital. Over 3,000 people looked on as the shovels hit the dirt at ... slidehsow. , During the program, Richard H. Hart, MD, DrPH, president, LLUH, recapped ...
(Date:5/24/2016)... ... May 24, 2016 , ... Eggsurance, ... the official relaunch of its community and education hub for women considering fertility ... is to create a safe and welcoming place for women to find cycle ...
(Date:5/24/2016)... ... May 24, 2016 , ... Tuesday, May 24, Women's Excellence in Wellness, powered ... Young Living Essential Oils, taught by Patti Dolan, RYT, a Young Living Gold ... Flow is 6:30pm - 7:15pm followed by a small intro to the Oils that ...
(Date:5/24/2016)... ... May 24, 2016 , ... In light of recent heavy flooding in Houston, ... contaminated well water throughout the Houston area. , Heavy floodwaters have led to destroyed ... to contaminants. Residents may not even be aware of the contamination of their water ...
Breaking Medicine News(10 mins):
(Date:5/23/2016)... 2016 Global Paclitaxel Market 2016 ... 12 companies and the Paclitaxel analysis in this study ... industry and its players. This is the ... details the current state of the industry while providing ... applications and industry chain structure. The Paclitaxel market analysis ...
(Date:5/23/2016)... May 23, 2016 According ... Share, Development, Growth and Demand Forecast to 2022 ... Other), by Application (Drug Discovery and Development, Proteomics, ... (Pharmaceuticals, Life Science and Biotechnology, Academic and Research ... Research, the global mass spectrometry market ...
(Date:5/23/2016)... , May 23, 2016 ... for detection of multiple diseases; ,Technology to be presented ... Yissum Research Development Company of the Hebrew ... into a research agreement with Aurum Ventures MKI, the technology ... development of a new diagnostic approach for early detection ...
Breaking Medicine Technology: