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Depression After Heart Attack Means More Heart Problems

e reuptake of the neurotransmitter serotonin in the brain; the medications have been shown to be safe and efficient in patients with heart disease. Serotonin affects emotions, mood and thought.

“In addition, improving social support, establishing a physical exercise regimen and addressing psychosocial issues, such as job situation, family conflicts and stress-causing health concerns, also may be necessary,” Dr. von K?nel said. “All of these things will work together to benefit quality of life, improve adherence to cardiac treatment and reduce health care costs.”

The next steps, Dr. von K?nel said, are to conduct additional research to ensure that patients receive the most effective treatments and to determine which of these treatments improve hard cardiovascular end-points, such as recurrent heart attack.

“There is no study showing to date that treatment of depression with psychotherapy improves cardiac or overall survival,” he said. “Non-randomized studies show, however, that SSRIs may benefit depressed patients after a heart attack in terms of improving cardiovascular outcome. A randomized double-blind, placebo-controlled trial with an antidepressant as well as an individually tailored psychotherapeutic intervention study are badly needed to resolve these issues.”
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