Navigation Links
Definite Connection Between Receptor Levels and Cocaine Abuse Reveals PET Imaging

Now, researchers adopting the technique of positron emission tomography (PET) have been able to confirm a link between a distinct character in the brain chemistry// and the susceptibility of an individual to resort to cocaine , to the extent of even becoming an addict.

The research, in animals, shows a significant correlation between the number of receptors in part of the brain for the neurotransmitter dopamine – measured before cocaine use begins – and the rate at which the animal will later self-administer the drug. The research was conducted in rhesus monkeys, which are considered an excellent model of human drug users.

Generally the lower the initial number of dopamine receptors, the higher the rate of cocaine use, the researchers found. The research was led by Michael A. Nader, Ph.D., professor of physiology and pharmacology at Wake Forest University School of Medicine.

It was already known that cocaine abusers had lower levels of a particular dopamine receptor known as D2, in both human and animal subjects, compared to non-users. But it was not known whether that was a pre-existing trait that predisposed individuals to cocaine abuse or was a result of cocaine use.

"The present findings in monkeys suggest that both factors are likely to be true," Nader and colleagues write in a study published online this week in the journal Nature Neuroscience. "The present findings also suggest that more vulnerable individuals are even more likely to continue using cocaine because of the cocaine-induced reductions in D2 receptor levels."

This was the first study ever to measure the baseline D2 levels of animals that had never used cocaine and compare those levels to changes in D2 receptors after the animals had started using. This kind of comparison is not possible with human subjects, and in previous monkey research, the brain chemistry of animals exposed to cocaine was compared only with non-using "controls."
<
'"/>




Page: 1 2 3

Related medicine news :

1. Obesity And Overweight Linked To Definite Cancer Risk
2. Definite Genetic Link Between Diabetes And Obesity Established
3. 3 –D Image of Influenza Virus – A Definite Breakthrouh
4. Dog Owners Definitely Healthier
5. MMR- Autism- Bowel Problems Connection To Be Investigated
6. Is There a Connection between Hearing loss and High-speed Dental Tools?
7. Studies Find Connection Between Acid Reflux And Esophageal Cancer
8. Connection between alcohol consumption and suicidal tendencies
9. Autism Connected to Improper Connections in Brain Cells
10. The Genetic Connection in Fatal Breast Cancers
11. A New Research Explores Connection Between Emotionality And Alcoholism
Post Your Comments:
(Date:7/25/2014)... Dental Perfection, a Derby cosmetic dentist ... general dentistry, clear braces and much more, has just ... in Derby. The new practice, which is scheduled to ... in Littleover, Derby. Patients may already pre-register for the ... dental practice, which is headed by Invisalign specialist and ...
(Date:7/25/2014)... (PRWEB) July 26, 2014 ... China Gel Permeation Chromatography Industry” is a ... Global and China Gel Permeation Chromatography market. ... information, including Gel Permeation Chromatography definition, classification, ... as industry overview. This research covers the ...
(Date:7/25/2014)... Los Angeles, CA (PRWEB) July 25, 2014 ... to talk about, and eager to reverse the symptoms associated ... health in the media at large, a new case ... the real benefits of testosterone therapy using bioidentical ... Jason, a 38-year-old father from Seattle who found himself beginning ...
(Date:7/25/2014)... 2014 American motor vehicle owners who ... can pay higher premiums for vehicle insurance on average. ... network to provide SR22 insurance for high risk motorists ... different coverage network of local agencies providing direct price ... platform now publicly available for any car owner to ...
(Date:7/25/2014)... As reported by the Statesman Journal in ... (7/20), police in Salem, MA as well as several ... recent heroin epidemic that has taken many lives during the ... overdose case in which police were able to make two ... By pretending to be the victim and claiming to want ...
Breaking Medicine News(10 mins):Health News:Derby Cosmetic Dentist Dental Perfection to Open New Practice in Littleover, Derby this September 2Health News:2014 China & Global GPC Industry - Gel Permeation Chromatography Development Trends Now at DeepResearchReports.com 2Health News:2014 China & Global GPC Industry - Gel Permeation Chromatography Development Trends Now at DeepResearchReports.com 3Health News:New Case Study Highlights Effectiveness of Testosterone Therapy in Fighting Weight Gain and Fatigue 2Health News:New Case Study Highlights Effectiveness of Testosterone Therapy in Fighting Weight Gain and Fatigue 3Health News:SR22 Insurance for High Risk Motorists Added to Local Quotes System at Insurer Website Online 2Health News:Multiple States Crack Down on Heroin Epidemic 2
... Calif., Dec. 8 Anesiva, Inc. (Nasdaq: ANSV ) ... with Arcion Therapeutics, Inc. ("Arcion") during its December 3, 2009 ... also approved a one-for-forty reverse stock split, which will be ... Closure of the merger remains contingent upon Anesiva achieving multiple ...
... PROVERI, Inc. is pleased to announce that it ... Venture Summit Top Innovator award by youngStartup Ventures. The list ... in innovation for the Technology, Life Sciences and Clean-tech sectors. , ... Executive Officer of PROVERI, Inc., will present the company at the ...
... , LONDON, Dec. 8 Over the past ... regarding the investment in healthcare information technology. Today, hospitals are ... in the Healthcare IT industry are in the process of ... an innovative product to market. At the same time, the ...
... , ANN ARBOR, Mich., Dec. ... revolutionary bench-top flow cytometer systems, today announced the 2009 recipients ... a free Accuri C6 Flow Cytometer® System each year to ... in Europe, who propose innovative uses of flow cytometry. ...
... ... 6.4 has just arrived. It offers new features for effectively working with Microsoft Office ... ... fanfare with interface updates and a powerful 64-bit capability. To date, InfoZoom has ...
... , LONDON, Dec. 8 Healthcare in ... of resources as the region,s working population is far lower in ... of new schemes in healthcare that would enable Europe to deal ... Information and Communication Technology (ICT) in healthcare is evident from the ...
Cached Medicine News:Health News:Anesiva Stockholders Approved Merger With Arcion Therapeutics but Merger Remains Contingent on Other Closing Conditions 2Health News:Anesiva Stockholders Approved Merger With Arcion Therapeutics but Merger Remains Contingent on Other Closing Conditions 3Health News:PROVERI, Inc. Named a Top Innovator Winner 2Health News:Frost & Sullivan to Hold Web Conference on Integrated Hospital Pharmacy Information Systems - How to Maneuver towards Growth Potential 2Health News:Innovative Applications of Flow Cytometry Win U.S. and European Researchers Free Accuri C6 Flow Cytometer(R) Systems 2Health News:Innovative Applications of Flow Cytometry Win U.S. and European Researchers Free Accuri C6 Flow Cytometer(R) Systems 3Health News:Innovative Applications of Flow Cytometry Win U.S. and European Researchers Free Accuri C6 Flow Cytometer(R) Systems 4Health News:InfoZoom Launches V6.4 of its Industry Leading In-Memory Data Analysis Software 2Health News:InfoZoom Launches V6.4 of its Industry Leading In-Memory Data Analysis Software 3Health News:Frost & Sullivan: E-Healthcare in Western Europe Presents a Significant Market Opportunity for Wireless Technologies 2Health News:Frost & Sullivan: E-Healthcare in Western Europe Presents a Significant Market Opportunity for Wireless Technologies 3
(Date:7/24/2014)... , Germany , and ... , Exclusive global license from ... SF3B1 mutations, including next-generation sequencing (NGS) gene panels, for ... be targeted by new test, indicate favorable prognosis for ... QIAGEN sees potential for developing companion diagnostics ...
(Date:7/24/2014)...  IRIDEX Corporation (NASDAQ: IRIX ) today ... financial results after the market closes on Thursday, ... the Company will host a conference call with the ... Thursday, July 31, 2014 to discuss ... Interested parties may access the live conference ...
(Date:7/24/2014)...  IGI Laboratories, Inc. (NYSE MKT: IG), a New Jersey ... financial results for the second quarter ended June 30, 2014. ... revenues of $6.5 million in the second quarter of 2014, ... , Total revenues of $13.3 million for the six ... the same period in 2013 , Total revenues generated ...
Breaking Medicine Technology:QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 2QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 3QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 4QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 5IGI Laboratories Announces Second Quarter 2014 Results 2IGI Laboratories Announces Second Quarter 2014 Results 3IGI Laboratories Announces Second Quarter 2014 Results 4IGI Laboratories Announces Second Quarter 2014 Results 5IGI Laboratories Announces Second Quarter 2014 Results 6IGI Laboratories Announces Second Quarter 2014 Results 7
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medicine Products: