Navigation Links
Defending against Tuberculosis

The deadliest bacterial pathogen may soon be fighting a losing battle. Scientists from Rockefeller University in New York say they have successfully stopped the tuberculosis pathogen's ability to operate from the immune system.// It typically hides out in the immune system in a cell called a macrophage.

The researchers say they have identified a new pathway (LRG-47) triggered by a host protein called interferon-gamma that disarms TB. Thus far, all of the research has been done in animals, but the researchers believe they have found a human equivalent of this pathway. They say LRG-47 is the correct pathway, because when they genetically remove it from the mice, they are then susceptible to TB infection.

According to experts, TB currently infects one-third of the human population and kills more people than any other bacterial pathogen. They write, "It is rivaled only by the acquired immunodeficiency syndrome (AIDS) virus as a communicable cause of death." Also, in developing countries, AIDS and TB go hand in hand. As many as 40 percent to 80 percent of AIDS patients will also develop TB.

Doctors know the protein interferon-gamma triggers a reaction of hundreds of genes, so they are still not quite sure which one is responsible for stopping TB. However, they say they are on the right path. One of the researchers, John McKinney, Ph.D. is quoted as saying: "One of the reasons we study the immune response to TB is to identify better treatments than those currently in use. This will occur only as a result of scientists' devoting more analysis to the bacteria's weaknesses and the host's strengths."
'"/>




Page: 1

Related medicine news :

1. Multi billion-dollar suit filed against cell phone firm for causing brain tumours
2. Man against HIV – new vaccine ready for human trials
3. Antibiotics losing their power against acne
4. South Africa Wins landmark case against pharmaceutical giants
5. Vitamin E, the latest warrior against diabetes
6. Acne may protect against infections
7. Fight against E.coli
8. Defence against free radicals
9. Progestin protects against ovarian cancer
10. Beverage protect against bladder cancer
11. Moderate alcohol consumption protects against dementia
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2017)... ... , ... Harris Communications, Inc., a leading provider of assistive technology for ... Deaf Seniors of America Conference, April 4-7 at the Hotel Westin Galleria in Houston. ... staff from Harris Communications and to try out the newest assistive devices available to ...
(Date:3/25/2017)... ... , ... Getting earned media coverage meaningful for Garden Media Group's clients is ... year, Garden Media aims to provide material helpful to clients’ goals and bottom lines. ... key messages to gain coveted media placements, Garden Media wows clients year-round. , ...
(Date:3/24/2017)... (PRWEB) , ... March 24, 2017 , ... ... solutions for contaminated soil, dredged material, and hazardous and non-hazardous materials announced today ... Allentown, Pennsylvania. This acquisition will add four additional processing facilities and a ...
(Date:3/24/2017)... ... March 24, 2017 , ... Mediaplanet today ... conversation on the current obstacles facing infection prevention and offer strategies for the ... by these infections. , The print component of “Fighting Infection” is distributed ...
(Date:3/24/2017)... ... March 24, 2017 , ... Digital Scientists, a software innovation lab specializing in ... a Greenville, South Carolina location. The lab has set up shop at ... been working with South Carolina clients for years from our office here in Atlanta,” ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... and BOSTON , March 27, ... global pharmaceutical company and Paratek Pharmaceuticals, Inc. (Nasdaq: ... and commercialization of innovative therapies based upon tetracycline ... of sarecycline for the treatment of moderate to ... endpoints. Sarecycline is a once-daily, oral, narrow spectrum ...
(Date:3/27/2017)... 27, 2017  PhaseRx, Inc. (NASDAQ: PZRX), a ... liver diseases in children, today reported financial results ... December 31, 2016 and provided an update on ... to make progress during the fourth quarter of ... our non-human primate safety study, and with our lead ...
(Date:3/24/2017)... , Mar 24, 2017 Research ... Therapy Manufacturing Market, 2017-2027" report to their offering. ... The Cell ... the rapidly growing market of cell therapy manufacturing and focuses ... manufacturing facilities. These therapies are anticipated to emerge as viable ...
Breaking Medicine Technology: