Navigation Links
Decrease of 'Hunger Hormone' after Obesity Surgery

According to researchers at the Puget Sound Health Care System, obese adults who undergo 'stomach stapling' have much lower levels of a recently discovered 'hunger hormone' than either normal-weight people or those who lose weight by dieting.//

Dr. David E. Cumming from the Puget Sound Health Care System in Seattle, suggested that drugs that suppress the hormone called ghrelin could curb appetite and may cut rates of obesity and related problems such as type 2 diabetes and other chronic disorders. He felt that, obesity is a huge problem and insights into the mechanisms of body weight regulation giving rise to treatments are very important," he said.

Ghrelin, a hormone produced by the stomach, is named for the Hindi word for growth. Past studies have shown it rises just before eating and falls after a meal and can make people so ravenous they eat nearly a third more food than usual. But it was not clear what happened to levels after dieting or in people who had gastric bypass surgery.

A team of investigators measured levels of ghrelin in the blood of 10 obese individuals before and after a 5-month weight loss program, in 6 adults who had lost weight after gastric bypass surgery, and in 10 normal-weight adults.

Patients had undergone a type of gastric surgery known as Roux-en-Y, in which a surgeon creates a small pouch in the stomach and also bypasses a portion of the small intestine. Afterwards, patients tend to eat less--and lose weight--because they feel full on less food.

But the surgery also appears to inhibit the production of ghrelin, thereby contributing to long-term weight loss. The finding may help explain why people undergoing surgery feel less hungry between meals, even though their intake of food has dropped dramatically.

After surgery, the patients had lower levels of the hormone compared with both normal-weight people and obese people who lost weight by dieting. For example, dieters who h ad a 30% weight loss--the equivalent of 34 pounds for a 200-pound woman--had a 24% increase in ghrelin levels compared with their pre-diet levels. In contrast, people who underwent surgery had ghrelin levels 80% lower than normal-weight people, even though they had a 30% weight loss.

Hormone levels also rose sharply before meals and declined after eating among obese dieters and normal-weight adults but remained steady in individuals who had surgery. Dr. Jeffrey S. Flier from Medical Center in Boston, Massachusetts notes that research into whether these drugs will mimic the effects of gastric bypass surgery or result in unexpected medical consequences is needed.

It is also unclear how gastric bypass surgery leads to a reduction in ghrelin levels. Nonetheless, the findings indicate that the hormone contributes to hunger and plays a key role in the long-term regulation of body weight, the study authors note. They concluded that their finding showed significant reduction of ghrelin levels after gastric bypass and thereby suggests that suppression of ghrelin can be studied as a potential mechanism by which this procedure causes weight loss.


'"/>




Related medicine news :

1. Decrease in testosterone levels lead to Alzheimers
2. Decrease in calories slows aging of the heart
3. Link Between Alcohol and Decrease in Brain Size
4. New Medication May Decrease The Frequency Of Angina Attacks
5. The Best Way To Decrease Post-Mammogram Stress
6. Frequent Mammograms Can Decreases The Risk of Death
7. Decrease in Brain Size Linked To Alcohol Consumption
8. Exercise Can Decrease Mental Decline
9. Stretching May Not Decrease Risk Of Injury In Power Sports
10. Chicken Eaters Have Decreased Risk Of Developing Colon Cancer
11. Decrease in Air Pollution Holds the Clue to Reduced Mortality
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/2/2016)... PA (PRWEB) , ... May 02, 2016 , ... As ... Healthsystem Association of Pennsylvania (HAP) issues its full support to allow certified nurse practitioners ... physician supervision after they have worked under such supervision for three years and 3,600 ...
(Date:5/2/2016)... ... 2016 , ... Amica Life Insurance Company has unveiled ... various life stages. , The site launched on April 1, and it has ... to the times when life insurance matters most. , “Through our research, we ...
(Date:5/2/2016)... (PRWEB) , ... May 02, 2016 , ... Dr. Philip ... his patients with same day treatments. In the past, many necessary dental treatments could ... work, along with multiple anesthetic shots and extra chair time. Not only could this ...
(Date:5/2/2016)... ... 2016 , ... Further establishing itself as a leader in natural pet products ... Boxes were selected from over 1,000 entrants as a winner and recipient of the ... chews for dogs are a favorite product among pet-parents worldwide, as each whimsical knobby ...
(Date:5/2/2016)... NEW PORT RICHEY, Fla. (PRWEB) , ... ... ... Pharmacology experts and medical researchers report that many commonly used prescription medications, ... memory loss (1). To mitigate these risks, Novus Medical Detox Center ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... 2016  The blood testing market in ... Kalorama Information and The Freedonia Group in a recent ... testing.  The healthcare research firm said that ... collection stations and in improving testing at the provincial ... Blood Testing Market in China , ...
(Date:4/28/2016)... -- , Net Sales of $1.90 billion represent an ... year period, and an increase of 1.2% on an adjusted ... the first quarter were $0.52 reported, a decrease of 47.5% ... of 29.9% over the prior year period , The ... 2016 Zimmer Biomet Holdings, Inc. (NYSE and SIX: ...
(Date:4/28/2016)... 28, 2016 Oramed Pharmaceuticals Inc. (NASDAQ: ... company focused on the development of oral drug delivery systems, ... PIONEERS 2016 conference, presented by Joseph Gunnar & ... New York . Nadav Kidron , CEO ... Presentation Details:   PIONEERS 2016, ...
Breaking Medicine Technology: