Navigation Links
Decrease in testosterone levels lead to Alzheimer's

Suppression of testosterone levels in men with testicular cancer may inadvertently increase the risk of Alzheimer’s disease, warn US researchers. A research team from North Carolina University has found that when circulating testosterone levels go down, a high rise in levels of amyloid – the protein implicated in Alzheimer’s disease – occurs. They suggest that this phenomenon might explain why Alzheimer’s develops later in life and that hormonal treatments for testicular cancer, which suppress testosterone levels, could potentially predispose individuals to this form of dementia.

In their study Dr Sam Chater and colleagues noted that all six men with testicular cancer who were treated by hormonal supression experienced an increase in plasma amyloid levels. Plasma amyloid roughly doubled over the six months of the investigation, say the researchers.//

Previous animal research by the team had shown that brain concentrations of amyloid increased significantly in female guinea pigs whose ovaries had been removed. Once hormone replacement therapy had been administered, the brain amyloid levels decreased.

Dr Chater said that people with a genetic predisposition to Alzheimer’s disease might have borderline amyloid levels until menopause, or the male equivalent andropause, reduces gonadal hormone secretion. “Brain amyloid levels may then rise enough to cause amyloid accumulation to begin,” he said.

A 8-year study is currently underway to investigate whether hormone replacement therapy can prevent the disease, with five-year interim results due in 2002. “If hormones are proven to be effective in this trial, then prevention of Alzheimer’s disease may become an indication for hormone replacement therapy in both men and women,” said Dr Sam.br>

'"/>




Page: 1

Related medicine news :

1. Decrease of Hunger Hormone after Obesity Surgery
2. Decrease in calories slows aging of the heart
3. Link Between Alcohol and Decrease in Brain Size
4. New Medication May Decrease The Frequency Of Angina Attacks
5. The Best Way To Decrease Post-Mammogram Stress
6. Frequent Mammograms Can Decreases The Risk of Death
7. Decrease in Brain Size Linked To Alcohol Consumption
8. Exercise Can Decrease Mental Decline
9. Stretching May Not Decrease Risk Of Injury In Power Sports
10. Chicken Eaters Have Decreased Risk Of Developing Colon Cancer
11. Decrease in Air Pollution Holds the Clue to Reduced Mortality
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/31/2016)... ... May 31, 2016 , ... ... announced it has been included by Gartner, Inc. in the Contact Center Infrastructure ... of Contact Center Infrastructure technologies, some of which include: Computer-telephony integration (CTI)/Web ...
(Date:5/31/2016)... ... May 31, 2016 , ... The University of ... Intelligence (AI) and the latest in Clinical Patient Pod (CPP) technologies ... analytic outputs directly into the clinical workflow. These insights are empowering the more ...
(Date:5/31/2016)... (PRWEB) , ... May 31, 2016 , ... ... commercial molecular diagnostics device that enables unprecedented portability and convenience. , The Cube ... four inches cubed in size, the Cube fits easily into any space, whether ...
(Date:5/31/2016)... ... May 31, 2016 , ... The Global Wellness Summit ... predictions on the future of wellness, travel, spa and beauty in Europe. The organization ... beauty companies to leading economists and researchers - to forecast where wellness is headed ...
(Date:5/31/2016)... ... May 31, 2016 , ... The Orthopaedic Research and Education Foundation ... , David G. Lewallen, MD, began his term as president in March, succeeding John ... MD, is OREF’s new president-elect. Richard F. Kyle, MD, will serve as chair, corporate ...
Breaking Medicine News(10 mins):
(Date:5/31/2016)... 2016 PaperHive Will Enable ... Elsevier,s ScienceDirect Database Elsevier , ... information products and services, today announced it will ... collaboration platform PaperHive to enable researchers to easily discover, ... on ScienceDirect , the world,s largest database ...
(Date:5/31/2016)... , Isansys  Lifecare, a new generation digital healthcare company, ... patient monitoring platform, as it ships more systems to hospitals in ... Scotland and Norway , ... earlier this year, is now being used in ground-breaking clinical ... new technology significantly enhances the user experience and provides higher ...
(Date:5/30/2016)... York , May 30, 2016 ... report titled, "Advanced (3D/4D) Visualization Systems Market - Global ... - 2024." According to the report, the global advanced ... Bn in 2015 and is anticipated to expand at ... reach US$ 3.2 Bn in 2024. Advanced ...
Breaking Medicine Technology: