Navigation Links
DNA-based Detection of Heavy Metals

Researchers at the University of Illinois at Urbana-Champaign have developed a simple, disposable sensor for detecting hazardous uranium ions,// with sensitivity that rivals the performance of much more sophisticated laboratory instruments.

The sensor provides a fast, on-site test for assessing uranium contamination in the environment, and the effectiveness of remediation strategies, said Yi Lu, a chemistry professor at Illinois and senior author of a paper accepted for publication in the Proceedings of the National Academy of Sciences, and posted on its Web site.

While most DNA is double stranded, the catalytic DNA Lu's research group uses has a single strand region that can wrap around like a protein. In that single strand, the researchers fashion a specific binding site -- a kind of pocket that can only accommodate the metal ion of choice.

In this case, the researchers chose to detect uranyl, the most soluble species of uranium ion and the one that poses the greatest threat to human life.

To search for the unique sequence of DNA that could distinguish uranyl from other metal ions, the researchers used a combinatorial approach called in vitro selection. Simple and cost-effective, the selection process can sample a very large pool of DNA (up to 1,000 trillion molecules), amplify the desired sequence by the polymerase chain reaction, and introduce mutations to improve performance.

Lu, with collaborators at Illinois, the Construction Engineering Research Laboratory, Oregon State University and Oak Ridge National Laboratory, assembled the uranium sensor and tested it on soils containing varying amounts of uranium.

The presence of uranyl causes catalytic cleavage of the DNA and release of the fluorophore, resulting in a dramatic increase of fluorescence intensity. With a detection sensitivity of 11 parts per trillion, the disposable sensor rivaled the performance of much more sophisticated laboratory
'"/>




Page: 1 2

Related medicine news :

1. Detection of Cancer
2. Early Detection Of Prostate Cancer
3. Early Detection of Lung Cancer
4. Early Detection of Prostate Cancer
5. Early Detection Of Facial Abnormalities in a Fetus
6. Early Detection Of Lung Cancer
7. Early Detection Of Breast Cancer
8. Do Not Neglect Your Abdominal Pain/ Swelling - Help Your Doctor In Early Cancer Detection
9. Patient Negligence - Significant Problem In The Early Detection Of Breast Cancer
10. Digital Mammogram For Detection Of Breast Cancer In Women With Dense Breasts
11. Early Detection Of Prostate Cancer For Complete Recovery From Prostate Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: DNA based Detection Heavy Metals

(Date:9/20/2014)... September 20, 2014 The print ... today’s edition of the Calgary Herald, with a ... readership of 270,000. The digital component is distributed ... across a network of top news sites and ... the campaign, visit http://www.worklifebalanceinfo.ca . , The ...
(Date:9/20/2014)... -- The avian flu that killed 160 harbor seals ... respiratory drops and therefore poses a potential threat to ... human illnesses have been linked to the harbor seal ... discovered natural mutations to the avian H3N8 seal virus ... in droplets. Current seasonal flu vaccines wouldn,t help ...
(Date:9/20/2014)... festival season is coming soon. The high-end fashion designer BellasDress ... dresses . A lot of sophisticated women like its new ... promotion for its high quality clothes. Now, each of its ... to 71 percent off. , The company’s cocktail dress ... in many fashionable colors. Mary, the company’s sales manager, believes ...
(Date:9/20/2014)... TX (PRWEB) September 20, 2014 ... Forecast and Market Analysis to 2023?. The asthma ... decade, as it has become saturated with relatively ... inhaled corticosteroids (ICSs), inhaled corticosteroids and long-acting beta-agonists ... facing increasing generic competition. However, the launch of ...
(Date:9/20/2014)... the popular online supplier of wedding dresses and special ... collection of cocktail gowns. This afternoon, the company announced ... outfits; it intends to expand its online market in ... cocktail dresses in the company’s online store. ... experience in the industry of women’s special occasion dresses. ...
Breaking Medicine News(10 mins):Health News:Getting ‘Wellthy’: Mediaplanet’s “Work-Life Wellness” campaign puts stock in the personal and economic gains of healthy, vital workplace environments for Canadians 2Health News:Avian Flu In Harbor Seals Could Infect People 2Health News:High-end Fashion Designer BellasDress Offers Luxurious Cocktail Dresses For Sophisticated Women 2Health News:Symbicort Asthma Market Forecasts to 2023 - Overview, Efficacy, Safety & SWOT Analysis in New Report Available at LifeScienceIndustryResearch.com 2Health News:Symbicort Asthma Market Forecasts to 2023 - Overview, Efficacy, Safety & SWOT Analysis in New Report Available at LifeScienceIndustryResearch.com 3Health News:Symbicort Asthma Market Forecasts to 2023 - Overview, Efficacy, Safety & SWOT Analysis in New Report Available at LifeScienceIndustryResearch.com 4Health News:Fashionable Cocktail Dresses Unveiled Online at iFitDress.com 2
... Dynatronics,Corporation (Nasdaq: DYNT ) today announced ... Mike Draper and Tom Draper, both of Wichita, ... as direct sales representatives. Dynatronics now offers ... our direct distribution presence is helping improve,profit margins ...
... BIRMINGHAM, Ala., Oct. 10 Aeon Bioscience,Inc. ... of its key,collaborators, Brookwood Pharmaceuticals, Inc. by ... to develop improvements in drug-eluting stent,technology for ... Bioscience was formed as a collaborative enterprise ...
... Achievement,and Innovation in Patient-Centered Approaches to Care, ... Hospital of,Warrenton, VA has been formally recognized ... Hospital." This designation,recognizes Fauquier,s achievement and innovation ... prioritizes patient comfort, dignity, empowerment,and well-being, while ...
... eHI Blueprint Offers Multi-Stakeholder Consensus on a Shared Vision, ... ... Through Information Technology, WASHINGTON, Oct. 10 Today the ... Common Action, which represents multi-stakeholder,consensus on a shared vision and ...
... A report to be published in an upcoming issue ... urgent attention to the politically sensitive issue of border control, ... the face of a catastrophic flu pandemic . The ... a strain of avian influenza A (HN51) in Northern Sumatra: ...
... Oct. 10 CBIZ, Inc. (NYSE: CBZ ) has,scheduled ... a.m.,(ET) to discuss the Company,s financial results for the third-quarter ... the,market opens the morning of October 25, 2007. At that ... Company,s web site at http://www.cbiz.com . The call ...
Cached Medicine News:Health News:Dynatronics Adds Three Additional Direct Sales Reps 2Health News:Aeon Bioscience Continues Development of Drug Eluting Stents 2Health News:Aeon Bioscience Continues Development of Drug Eluting Stents 3Health News:Aeon Bioscience Continues Development of Drug Eluting Stents 4Health News:Fauquier Hospital - One of Only Five Nationwide to Receive Formal Designation as Patient-Centered Hospital 2Health News:Fauquier Hospital - One of Only Five Nationwide to Receive Formal Designation as Patient-Centered Hospital 3Health News:eHealth Initiative Releases Blueprint Representing Consensus on an Action Plan for Transforming U.S. Healthcare Using Health IT 2Health News:eHealth Initiative Releases Blueprint Representing Consensus on an Action Plan for Transforming U.S. Healthcare Using Health IT 3Health News:eHealth Initiative Releases Blueprint Representing Consensus on an Action Plan for Transforming U.S. Healthcare Using Health IT 4Health News:Report highlights inadequate pandemic planning as a threat to EU security 2Health News:CBIZ Webcasts Third-Quarter 2007 Conference Call 2
(Date:9/19/2014)... Research and Markets has announced the addition of the ... Disorder) Market - Forecast to 2023" report to their ... human microbiome market is segmented by application, disease, product, and ... be valued as $294 million in 2019 and is poised ... period of 2019-2023. The market is driven by growing incidences ...
(Date:9/19/2014)... 19, 2014 UBM Medica US announces that  ... community to help oncologists and other clinicians gain a ... use of targeted therapies and immunotherapies, discusses some of ... Every September, Blood Cancer Awareness ... awareness about blood cancers—helping to increase survival rates and ...
(Date:9/19/2014)... , Sept. 19, 2014  Alere Inc. (NYSE: ... issued the following statement today in support of President ... "As the global leader in rapid diagnostics ... a national strategy to address the serious threat of ... with the Administration on initiatives to promote the development ...
Breaking Medicine Technology:Global Human Microbiome (Diabetes, Obesity, Autoimmune, Cancer, Diarrhea, Mental Disorder) Market - Forecast to 2023 2Global Human Microbiome (Diabetes, Obesity, Autoimmune, Cancer, Diarrhea, Mental Disorder) Market - Forecast to 2023 3OncoTherapy Network Highlights National Blood Cancer Awareness Month 2OncoTherapy Network Highlights National Blood Cancer Awareness Month 3OncoTherapy Network Highlights National Blood Cancer Awareness Month 4Alere Applauds President's Executive Order Combating Antibiotic-Resistant Bacteria 2
Ultra-Slip™ endotracheal tube guide for single-patient use only., ,Caution: Not MRI Compatible....
FlexiSlip™ Plastic coated malleable metal core. Single use, Sterile, Latex Free. Soft distal tip flexes to reduce risk of trauma to patient. Malleable metal core is easy to shape. Low friction ...
Endotracheal Tube Stylet- Adult, Copper, Malleable, Non-Sterile, Latex Free, Suitable for tubes 5.0 mm I.D. or larger....
... Requires minimal cervical spine manipulation. Prevent dental ... nasally. Cost effective alternative to X-ray. Light-guided ... the soft tissues in the neck. This ... of the trachea relative to the esophagus. ...
Medicine Products: