Navigation Links
Curcumin –New Weapon Against Colorectal Cance

Curcumin has been found to reduce the activity of a fat-induced gastrointestinal hormone that promotes the growth and spread of colorectal cancer cells// according to researchers at the Texas University Medical Branch at Galveston.

Researchers from the University of Texas Medical Branch at Galveston (UTMB) found the anticancer property of curcumin, on examining the link between gastrointestinal hormone, neurotensin and the production of an inflammatory protein that boosts the growth of a variety of cancer cells.

The study published in the current issue of Clinical Cancer Research revealed that curcumin inhibits neurotensin-mediated production of interleukin-8 and migration of HCT116 human colon cancer cells, which has led to the inference that curcumin may help stop growth of colorectal cancer cells, and prevent its spread to other locations in the body.

IL-8 is a potent inflammatory protein which accelerates the growth and spread of a variety of human cancer cells, including colorectal and pancreatic tumor cells. According to the researchers curcumin reduces IL-8 production by inhibiting the signals neurotensin needs to have an effect on IL-8 production.

UTMB surgery professor B. Mark Evers, senior author of the article and director of UTMB's Sealy Center for Cancer Cell Biology said, "We found that in colon cancer cells, neurotensin increases not just the rate of growth but also other critical things, including cell migration and metastasis."

Curcumin is the yellow pigment found in turmeric, which is a commonly used spice in Indian cuisine and traditional medicine. The low incidence of cancer in India has led several researchers to believe that curry may have certain anticancer functions. Early lab studies have revealed that curcumin fights skin, breast and other tumor cells.

According to a study published in the Oct. 15 2005 issue of the journal Clinical Cancer Research, Curcumin inhibits the spr ead of breast cancer to the lungs in mice, The study authors reported that while curcumin not only prevents the progression of breast cancer cells, the adverse effects of Taxol, a breast cancer drug that can trigger spread of breast cancer is aldo reversed.

In another study Dr. Razelle Kurzrock at University of Texas and colleagues successfully treated three melanoma cell lines with curcumin finding that treatment of curcumin induces the death of cancer cells in a dose-responsive manner.

In the United States, diagnosis of colorectal cancer was made in 70,651 men and 68,883 women in 2002 and 28,471 men and 28,132 women, according to the Centers for Disease Control and Prevention. Some of the common risk factors towards colorectal cancer include lack of regular physical activity, obesity low fruit and vegetable intake, as well as alcohol consumption and tobacco use.

Related medicine news :

1. The effects of Curcumin: a natural pigment in turmeric explored for its anti-cancer properties
2. Curcumin found to halt spread of breast cancer in mice
3. Anticancer Effects of Curcumin Revealed
4. Smallpox as Biological Weapons?
5. New Weapon Against Germs
6. Turmeric and Onions-Weapons against Colon Cancer
7. Researchers Find Secret Weapon Used by SARS Virus
8. Latest Weapon in Battle against Drug-Resistant Bacteria
9. NRI Scientists find Potential Colon Cancer Weapon
10. Battle against Gum Disease Acquires new Weapon
11. Cellular Pathway Yields Potential New Weapon in Vaccine Arsenal
Post Your Comments:

(Date:11/25/2015)... ... November 26, 2015 , ... Ministers, senior government and UN ... African Centres of Excellence, and public R&D institutions, civil societies and other partners ... the 5th African Network for Drugs and Diagnostics Innovation, ANDI, Stakeholders Meeting. The ...
(Date:11/25/2015)... , ... November 25, 2015 , ... According to an ... robot is being more and more widely heralded as a breakthrough for performing hernia ... method has over traditional laparoscopic surgery is that it can greatly reduce the pain ...
(Date:11/25/2015)... ... 2015 , ... On November 25, 2015, officials of Narconon Arrowhead , ... release of a new cutting edge recovery program that has been 50 years in ... and alcohol-addicted individuals with the purpose to free addicts from the symptoms and negative ...
(Date:11/25/2015)... ... ... On November 23rd 2015 Cozy Products, a division of Bird-X ... Products explains what this means for business moving forward. , The Tri Lite heater ... model: to sell personal heaters that reduce energy consumption, are economical and keep people ...
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... Beddit® has ... Beddit Classic sleep tracking systems. The new app features a more intuitive SleepScore™ that ... understand how well you slept. The SleepScore is created by a proprietary algorithm. Beddit ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... SYDNEY , Nov. 26, 2015  The total global ... nearly 7% over 2015-2016. Latin America ... Asia , (excluding Japan ), is ... continues to face increased healthcare expenditure. In 2013-2014, ... expenditure declined from 43.5% in 2008-2009 to 41.2% in 2013-2014. ...
(Date:11/25/2015)... Nov. 25, 2015 On Tuesday, November ... bellwether trial against Wright Medical Technology, Inc. for ... Conserve metal-on-metal hip implant device, awarded $11 million ... two week trial and three days of deliberations, ... device was defectively designed and unreasonably dangerous, and ...
(Date:11/25/2015)... 25, 2015  Trovagene, Inc. (NASDAQ: TROV ), ... Chief Executive Officer Antonius Schuh, Ph.D., is scheduled to ... Annual Piper Jaffray Healthcare Conference. th ... Palace Hotel in New York ... Mr. Schuh will be available for one-on-one meetings during ...
Breaking Medicine Technology: