Navigation Links
Curcumin –New Weapon Against Colorectal Cance

Curcumin has been found to reduce the activity of a fat-induced gastrointestinal hormone that promotes the growth and spread of colorectal cancer cells// according to researchers at the Texas University Medical Branch at Galveston.

Researchers from the University of Texas Medical Branch at Galveston (UTMB) found the anticancer property of curcumin, on examining the link between gastrointestinal hormone, neurotensin and the production of an inflammatory protein that boosts the growth of a variety of cancer cells.

The study published in the current issue of Clinical Cancer Research revealed that curcumin inhibits neurotensin-mediated production of interleukin-8 and migration of HCT116 human colon cancer cells, which has led to the inference that curcumin may help stop growth of colorectal cancer cells, and prevent its spread to other locations in the body.

IL-8 is a potent inflammatory protein which accelerates the growth and spread of a variety of human cancer cells, including colorectal and pancreatic tumor cells. According to the researchers curcumin reduces IL-8 production by inhibiting the signals neurotensin needs to have an effect on IL-8 production.

UTMB surgery professor B. Mark Evers, senior author of the article and director of UTMB's Sealy Center for Cancer Cell Biology said, "We found that in colon cancer cells, neurotensin increases not just the rate of growth but also other critical things, including cell migration and metastasis."

Curcumin is the yellow pigment found in turmeric, which is a commonly used spice in Indian cuisine and traditional medicine. The low incidence of cancer in India has led several researchers to believe that curry may have certain anticancer functions. Early lab studies have revealed that curcumin fights skin, breast and other tumor cells.

According to a study published in the Oct. 15 2005 issue of the journal Clinical Cancer Research, Curcumin inhibits the spr ead of breast cancer to the lungs in mice, The study authors reported that while curcumin not only prevents the progression of breast cancer cells, the adverse effects of Taxol, a breast cancer drug that can trigger spread of breast cancer is aldo reversed.

In another study Dr. Razelle Kurzrock at University of Texas and colleagues successfully treated three melanoma cell lines with curcumin finding that treatment of curcumin induces the death of cancer cells in a dose-responsive manner.

In the United States, diagnosis of colorectal cancer was made in 70,651 men and 68,883 women in 2002 and 28,471 men and 28,132 women, according to the Centers for Disease Control and Prevention. Some of the common risk factors towards colorectal cancer include lack of regular physical activity, obesity low fruit and vegetable intake, as well as alcohol consumption and tobacco use.
NLA
'"/>




Related medicine news :

1. The effects of Curcumin: a natural pigment in turmeric explored for its anti-cancer properties
2. Curcumin found to halt spread of breast cancer in mice
3. Anticancer Effects of Curcumin Revealed
4. Smallpox as Biological Weapons?
5. New Weapon Against Germs
6. Turmeric and Onions-Weapons against Colon Cancer
7. Researchers Find Secret Weapon Used by SARS Virus
8. Latest Weapon in Battle against Drug-Resistant Bacteria
9. NRI Scientists find Potential Colon Cancer Weapon
10. Battle against Gum Disease Acquires new Weapon
11. Cellular Pathway Yields Potential New Weapon in Vaccine Arsenal
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/5/2016)... Seattle, WA (PRWEB) , ... February 05, 2016 ... ... consulting firm, ranked #3 in the 2015 Best in KLAS: Software & Services ... The annual Best in KLAS report independently ranks vendor performance by healthcare ...
(Date:2/5/2016)... ... , ... Stuart Bentkover, MD, FACS is thrilled to announce the ... effective tattoo removal today, Dr. Bentkover is the only doctor in Central Massachusetts to ... has been approved by the Food and Drug Administration (FDA) as a safe and ...
(Date:2/5/2016)... ... ... In sleep, when the defenses of the day are at rest, rejected emotions ... disorders is significant self-criticism, and consequently these patients experience this disease with their feelings, ... for coping with this unease, but also leads to a reservoir of emotions that ...
(Date:2/5/2016)... Ramsey, NJ (PRWEB) , ... February 05, 2016 ... ... Optimizing Primary Care for Patients with Rare Diseases, a continuing medical education (CME) ... conference is the first of its kind—and a first for ACCORD, whose mission ...
(Date:2/5/2016)... ... 2016 , ... –This week, Atascadero water heater company First Call Plumbing ... To view the report, click here or see below. , There ... pros and cons, the type chosen is almost entirely up to personal preference. However, ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... France , Germany , Italy ... ). It includes a 10-year epidemiology forecast for the total prevalent ... sex in these markets. GD epidemiology report is written and developed by ... and market-driven, providing expert analysis of disease trends in the 7MM. ... Italy , Spain , UK, and ...
(Date:2/4/2016)... 2016  The Senior Care Pharmacy Coalition (SCPC) ... Chairman Jason Chaffetz (R-UT) and Ranking ... hearing , "Developments in the Prescription Drug Market," ... questions about abusive pharmacy benefit manager (PBM) pricing ... Ranking Member Elijah Cummings (D-MD) are diligent, serious ...
(Date:2/4/2016)... , Feb. 4, 2016 Wegener ... Global Markets Direct,s, ,Wegener Polyangiitis - Pipeline ... Wegener Polyangiitis,s therapeutic pipeline. This report provides ... Polyangiitis, complete with comparative analysis at various stages, ... (MoA), route of administration (RoA) and molecule type, ...
Breaking Medicine Technology: