Navigation Links
Crucell's Rabies MAb Enters Phase I Trial in India

Dutch biotechnology company, Crucell N V’s Rabies monoclonal antibody (mAb) product has entered a phase I clinical study in India, four months after launching// a similar study in the US.

Crucell has developed a human monoclonal antibody product for the post-exposure prophylaxis of rabies, using Crucell’s MAbstract and Crucell’s PER.C6 technologies. This second phase I study is closely linked to the initial phase I study that is currently being performed in the US. Both studies are conducted under FDA authority, the Indian phase I study gained approval upon review by the Drug Controller-General of India (DCGI).

The clinical trial will be a randomized, double-blind, placebo controlled study in 44 healthy volunteers that will test the antibody product alone in a dose escalation as well as in combination with rabies vaccine. The study, funded by Crucell, will be conducted through a undisclosed clinical research organization in Mumbai, India. The main parameters under investigation will be safety, tolerability and rabies virus neutralizing activity.

“We are very pleased that would could initiate this second phase I trial, as it follows favorable interim safety and tolerability data from the initial US study. The clinical testing of the Rabies antibody cocktail in Asia is the next important step for the program, as the global burden of Rabies is mostly affecting this continent. In addition to clinical evaluation of the rabies mAb cocktail in India, we are currently exploring the conduct of clinical trials in other Asian countries, including China,” said Mr Jaap Goudsmit, Chief Scientific Officer at Crucell.

Dr Deborah Briggs, Director of the Alliance for Rabies Control opined that there is a tremendous need for additional sources of rabies immune globulins (RIG) throughout the world, especially in Asia where less than three percent of patients undergoing post-exposure prophylaxis actually receive passive immune produ
'"/>




Page: 1 2

Related medicine news :

1. Transfer Of Rabies Virus Possible From Organ Donor To Recipient
2. Rabies Requires Immediate Treatment
3. Student Bitten By Bat And Diagnosed With Rabies In Critical Condition
4. WB Asks Centre To Continue Supply Of Anti-Rabies Vaccine
5. Community Awareness Is Imperative For Eradication Of Rabies
6. Digital ID Chips Implanted in Dogs to Prevent Rabies
7. International Collaboration Takes Aim at Rabies
8. Bharat Biotech Launches Anti-Rabies Vaccine
9. WHO on an Anti Rabies and Snake Bite Mission
10. More Indians Die of Rabies Annually
11. New Vaccine to Tackle Rabies in Dogs
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Crucell Rabies MAb Enters Phase Trial India

(Date:9/17/2014)... -- Present-day Europeans are the descendants of at ... a new study. Previous research suggested ... European farmers. But, a new genetic analysis involving ... descendants of Ancient North Eurasians. Nearly all present-day ... group, researchers from Harvard Medical School said. , ...
(Date:9/17/2014)... WEDNESDAY, Sept. 17, 2014 (HealthDay News) -- Managing diabetes, ... a healthy weight can reduce the risk for dementia ... The World Alzheimer Report 2014, commissioned by ... risk of dementia by 50 percent. The study noted ... factors for diabetes as well as high blood pressure. ...
(Date:9/17/2014)... HealthDay Reporter WEDNESDAY, Sept. 17, ... to artificial sweeteners to soothe their sweet tooth may ... study suggests. Artificial sweeteners can potentially make blood ... in human and mouse studies. That,s because saccharine ... in the intestines in ways that can impair some ...
(Date:9/17/2014)... COLUMBUS, Ohio Mathematics might be able to reduce ... damage related to the autoimmune disease lupus. , In ... can predict the progression from nephritis kidney inflammation ... current treatments cannot reverse. A kidney biopsy is the ... the damage and its extent. , The model could ...
(Date:9/17/2014)... Research has shown that most 18-month-olds learn an average ... little is known about how children process information to ... years. In a new study, a University of Missouri ... they age, and a limit exists as to how ... could help parents enhance their children,s vocabularies and assist ...
Breaking Medicine News(10 mins):Health News:Europeans Are Descendants of at Least 3 Ancient Human Groups: Study 2Health News:Europeans Are Descendants of at Least 3 Ancient Human Groups: Study 3Health News:Healthy Lifestyle Changes Linked to Reduced Risk for Dementia 2Health News:Healthy Lifestyle Changes Linked to Reduced Risk for Dementia 3Health News:Artificial Sweeteners May Raise Blood Sugar Levels: Study 2Health News:Artificial Sweeteners May Raise Blood Sugar Levels: Study 3Health News:Math model designed to replace invasive kidney biopsy for lupus patients 2Health News:Babies learn words differently as they age, researcher finds 2
... Blacksburg, Va. -- A new yew species that grows in ... Kingston, University Distinguished Professor of Chemistry in Virginia Tech,s College ... was described by Richard Spjut in a major review of ... Institute of Texas. , The author says, Taxus kingstonii ...
... small businesses and ... individuals, ... Milwaukee, WI-based national provider of,individual medical, small group and specialty health ... announced today the formation of a new health care network., ...
... CHICAGO, Nov. 27 The past decade has seen ... pregnant women,according to a study presented today at the ... "Through medical imaging examinations, we are exposing pregnant ... 10 years ago," said Elizabeth,Lazarus, M.D., assistant professor of ...
... Vision Reach to be deployed at 92 outpatient imaging ... centers ... AMCS ),a leader in radiology and medical image and information ... diagnostic imaging services, has chosen AMICAS Vision,Series(TM) PACS as the platform ...
... drug recall notice -- creating a,new paradigm for the ... safety,experts, including representatives from the Center for Medicine in ... will gather,at the National Press Club and call for ... individualized information about the risks and,benefits of drugs on ...
... the American Lung Association,s Faces of Influenza Program to ... Urge Immunization throughout the Season, ... up 20% of the population, or 757,000 people, are estimated ... Americans are,recommended for annual vaccination, immunization rates fall short every,year, ...
Cached Medicine News:Health News:Tree named in honor of Virginia Tech chemist David G.I. Kingston 2Health News:Low-Cost Health Care Network Launches in Lubbock 2Health News:Low-Cost Health Care Network Launches in Lubbock 3Health News:Radiation Exposure of Pregnant Women More than Doubles in 10 Years 2Health News:Radiation Exposure of Pregnant Women More than Doubles in 10 Years 3Health News:MedQuest Standardizes on AMICAS Vision Series PACS 2Health News:MedQuest Standardizes on AMICAS Vision Series PACS 3Health News:Drug Safety Experts Call for Increased Patient Involvement 2Health News:Drug Safety Experts Call for Increased Patient Involvement 3Health News:Phoenix Fire Chief Bob Khan Encourages Arizonans to Get Vaccinated Against Influenza 2Health News:Phoenix Fire Chief Bob Khan Encourages Arizonans to Get Vaccinated Against Influenza 3Health News:Phoenix Fire Chief Bob Khan Encourages Arizonans to Get Vaccinated Against Influenza 4
(Date:9/17/2014)... Sept. 17, 2014  Millions of people suffer from neck ... Recently the FDA approved the launch of ... innovative implant device developed by Spinal Kinetics, which may offer ... and or arm pain. Hospital for Special Surgery (HSS), the ... hospital in New York City and ...
(Date:9/17/2014)... According to a new market research report ... Display, & Microprocessor/MCU), by Application (Imaging, Medical Therapeutics, Diagnosis, ... Global Forecast to 2020", published by MarketsandMarkets, the total ... $56.50 Billion by 2020, growing at a CAGR of ... market data Tables and 71 Figures spread through 312 ...
(Date:9/17/2014)... N.J. , Sept. 17, 2014  The ... (MDM&C), today announced that it will serve as ... Benefits and Avoiding the Risks of Healthcare Reform," ... that will examine delivery systems, reimbursement, compliance and ... Care Act. Logo -  http://photos.prnewswire.com/prnh/20140916/146606 ...
Breaking Medicine Technology:Cervical Disc Clinical Trial for People with Neck and Arm Pain Set to Begin at Hospital for Special Surgery 2Medical Electronics Market Worth $56.50 Billion by 2020 2Medical Electronics Market Worth $56.50 Billion by 2020 3Medical Electronics Market Worth $56.50 Billion by 2020 4Three Leading Healthcare Organizations Sponsor Conference to Examine Opportunities and Risks of Healthcare Reform for Providers 2
... Pa., Jan. 12, 2011 ECRI Institute® ( ... the best approaches to improving patient care, is ... Health Devices Achievement Award program. The award ... technology management. (Logo: http://photos.prnewswire.com/prnh/20110112/DC29081LOGO ...
... 2011, what will be the major trends in the ... regulations affect what,s next and what,s new?  What will ... competitive corporate landscape?  When it comes to market research, ... the job done right? The answers to these questions ...
Cached Medicine Technology:ECRI Institute's 2011 Health Devices Achievement Award - Call for Entries 2ECRI Institute's 2011 Health Devices Achievement Award - Call for Entries 3Pharma Industry Leaders to Reveal Hottest, Latest Trends for Pharma & Biotech at Groundbreaking Event 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: