Navigation Links
Crohns Disease Could Be Caused By Gaps In The Intestinal Barrier

The human bowel is lined with millions of projections called villi which increase the surface area of the intestine to allow for the efficient absorption of nutrients. The villi are covered in epithelial cells // which are constantly renewed – around a thousand billion cells are shed from the top of the villi every day.

Scientists found that this renewal process leaves 'gaps' in the lining of the bowel which, in healthy tissue, are immediately filled with a glue-like substance that plugs the gaps. This is in contrast to the previous assumption that the lining of the intestine was a continuous sheet of cells. The existence of gaps has been discovered for the first time and around 3% of the bowel's surface area is covered in this substance. It was previously assumed that the It is believed that gaps in the intestinal barrier could be a cause of inflammatory diseases of the gut such as Crohn's Disease, which could have important implications for the treatment. Crohn’s disease is an inflammatory bowel disorder that causes severe ulceration in the intestine, leading to pain, bleeding and diarrhoea.

It is suspected that patients with inflammatory disease may not have the same ability to plug the gaps left by the cell renewal process – meaning that bacteria can seep through the lining of the intestine. The research may also explain the development of colon cancer as a result of failure in the renewal process of epithelial cells.

Understanding this cell shedding process may lead to new treatments for inflammatory bowel disease and perhaps even colon cancer in future.

'"/>




Page: 1

Related medicine news :

1. Transdermal HRT not cardioprotective in postmenopausal women with Coronary Artery Disease
2. Vitamins-The answer to Heart Disease?
3. Link between Constipation and Parkinsons Disease
4. Levels Of Blood Proteins May Help Heart Disease Care
5. New Drug PP188 Helps Sickle Cell Disease
6. Gene Treatment for Heart Disease
7. Legume Consumption Can Cut Heart Disease Risk
8. Link Between Infection And Heart Disease
9. Celiac Disease in Type 1 Diabetes
10. Shunt for Alzheimers Disease
11. High iron levels may cause Cardiovascular Disease in women
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/21/2017)... ... , ... Chicago plastic surgeon, Dr. Anil R. Shah, MD , has ... bony lump located on the forehead usually attributed to a facial fracture. Their appearance ... Dr. Shah has discovered an approach that is minimally invasive. He is an expert ...
(Date:4/21/2017)... (PRWEB) , ... April 21, 2017 , ... Dudnyk has ... identity emphasizes the agency’s conviction that the full potential of specialty and orphan brands ... equally appreciated and aligned. , “The Unifying Effect is at the heart of ...
(Date:4/21/2017)... ... April 21, 2017 , ... The Hong Kong Polytechnic ... 3D printing facility among higher education institutions in Hong Kong to support teaching, learning ... of the range and quantity of facilities in Hong Kong. , With an ...
(Date:4/21/2017)... ... April 21, 2017 , ... Airway ... new partnership with the highly regarded and well renowned Asian distributor, Discovery Sleep. ... & myTAP PAP Nasal Pillow Mask, and will stabilize and strengthen Airway’s presence ...
(Date:4/21/2017)... , ... April 21, 2017 , ... Providing for loved ... the estate planning process, or where to even begin. “Now more than ever there ... are to properly protect yourself and your family,” said attorney Lisa Edgar Dickman, founder ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)...  Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH), ... it will be participating in the Deutsche Bank Securities ... in Boston, Massachusetts on Wednesday, ... a.m. Eastern Time. A live webcast of ... Relations website at http://investor.zimmerbiomet.com .  The webcast will ...
(Date:4/20/2017)... 2017  CVS Pharmacy, the retail division of ... store design to enhance the retail customer experience ... products and expanded beauty selections paired with informational ... new offerings. Together with its innovative digital programs, ... customer experience at CVS Pharmacy.  ...
(Date:4/20/2017)... -- Eyevensys, a private biotechnology company developing ... technology that enables the safe, local, sustained production of ... range of ophthalmic diseases, announces it has received approval ... (MHRA) to advance its technology into clinical development. ... The EyeCET platform ...
Breaking Medicine Technology: