( on morbidity and mortality in older pat...)Coversyl Demonstrates Clinical Benefits in Elderly Patients,Health

on morbidity and mortality in older patients withclinical evidence of heart failure secondary to left ventricular diastolic dysfunction.

Coversyl initiation was well tolerated among this elderly population. In the span of one year, 65 patients assigned to placebo and 46 assigned to Coversyl experienced a primary outcome event. By the end of follow-up, although there was no statistical significance between the two groups, nearly half of these elderly patients had stopped their study medication (placebo or Coversyl) and most of whom went on to receive open label ACE inhibitors. It was found that in spite of the high rate of cross-over, patients assigned to Coversyl spent about 5 fewer days in hospital for any reason and 3 fewer for cardiovascular reasons.

Coversyl initiation was well tolerated among this elderly population. In the span of one year, 65 patients assigned to placebo and 46 assigned to Coversyl experienced a primary outcome event. By the end of follow-up, although there was no statistical significance between the two groups, nearly half of these elderly patients had stopped their study medication (placebo or Coversyl) and most of whom went on to receive open label ACE inhibitors. It was found that in spite of the high rate of cross-over, patients assigned to Coversyl spent about 5 fewer days in hospital for any reason and 3 fewer for cardiovascular reasons.

In one year, patients who received active treatment were found to be more likely to have improved New York Heart Association (NYHA) functional class (p<0.03). Besides this it was found that patients who were given Coversyl had a greater increase in 6-minute corridor walk distance at one year. This trial showed that a treatment, Coversyl, can improve symptoms and functional capacity in patients with diastolic heart failure.

Coversyl is the first agent to demonstrate clinical benefits in such a population.


NLA
'"/>




Page: 1 2
Related medicine news :

1. Mouse Model Demonstrates Immune System Reaction In Chlamydia Infection
2. A New Research Demonstrates HIV-1 In Resident Immune Cells Of Human Testis
3. New Therapy for Lipid Disorder Demonstrates Varied Results
4. Clinical trials need to be more frank
5. Physicians Lack Clinical Guidelines For Treating Elderly With Multiple Illnesses
6. The Growing Rise In Clinical Research Could Lead To A Compromise In Quality Of Research And Ethics
7. Clinical Comparisons Between ADHD Drugs Are Less
8. A Novel System For Clinical Banking Of Umbilical Cord Blood
9. Clinical Renal Trails Do Not Have Sufficient Women Participants
10. Clinical Trials of New Drug Febuxostat Show Promise in Gout Treatment
11. Clinical Trials Of New Anti-Cancer Drug To Be Initiated In New Zealand