nstructions from an eye care professional.
* Use fresh cleaning or disinfecting solution each time lenses are cleaned and stored. Never reuse or top off old solution.
* Never use saline solution and rewetting drops to disinfect lenses. Neither solution is an effective or approved disinfectant.
* Store reusable lenses in the proper storage case.
* Storage cases should be rinsed with sterile contact lens solution (never use tap water) and left open to dry after each use.
* Replace storage cases at least once every three months
Clinicians evaluating contact lens users with symptoms of eye pain or redness, tearing, decreased visual acuity, discharge, sensitivity to light, or foreign body sensation should consider AK and refer the patient to an ophthalmologist, if appropriate. Diagnosis requires a high degree of suspicion, especially in a contact lens wearer with a recent diagnosis of another form of keratitis, such as herpes simplex virus keratitis, who is not responding to therapy.
Diagnosis is made on the basis of clinical picture and isolation of organisms from corneal culture or detection of trophozoites and/or cysts on histopathology. However, a negative culture does not necessarily rule out Acanthamoeba infection. Confocal microscopy and polymerase chain reaction assays to detect Acanthamoeba may also assist with diagnosis. Early diagnosis can greatly improve treatment efficacy.
Clinicians should consider obtaining clinical specimens (e.g., corneal scrapings) for culture before initiating treatment. Clinicians or microbiology laboratories should report cases of AK to state and local health departments or directly to CDC.
Acanthamoeba isolates should be submitted to state laboratories according to instructions provided by local and state public health laboratories, CDC said.
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