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Complex Apnea May Explain Sleepless Nights

or development of a prominent and disruptive Cheyne-Stokes respiratory pattern.

They diagnosed complex sleep apnea if CPAP titration eliminated events defining obstructive apnea, but patients still had a residual central apnea index of 5 per hour or more, or development of a prominent and disruptive Cheyne-Stokes respiratory pattern.

heir study revealed that the prevalence of obstructive apnea was 84% in the one-month sample population, compared with 15% for complex apnea, and 0.4% for central apnea. The diagnostic apnea-hypoapnea index for the complex syndrome was 32.3±26.8, compared with 20.6±23.7 for obstructive apnea, and 38.3±36.2 for central apnea (P=0.005).

The researchers reported, "Patients with complex sleep apnea syndrome are mostly similar to those with obstructive sleep apnea-hypoapnea syndrome until one applies CPAP. Like patients having obstructive sleep apnea hypoapnea syndrome, they differ from patients with central sleep apnea in that they have less sleep maintenance insomnia."

They concluded that Neither the pathophysiologic mechanisms nor optimal treatment for patients with complex sleep apnea are known.


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