( A new study has found that combination ...)Combo Therapy may Be Highly Beneficial in Asthma Control,Health

A new study has found that combination asthma therapy, SYMBICORT leads to significant improvements in health-related quality of life (HRQL) and greater patient-reported satisfaction with asthma treatment, versus its monocomponents (budesonide or formoterol or placebo).

SYMBICORT is a recently approved, combination therapy indicated for the long-term maintenance treatment of asthma in patients 12 years of age and older. SYMBICORT does not replace fast-acting inhalers and should not be used to treat acute symptoms of asthma.

SYMBICORT is a combination of two proven asthma medications budesonide, an inhaled corticosteroid (ICS), and formoterol, a rapid and long-acting beta agonist (LABA).

As part of the 12-week, randomised, double-blind, placebo-controlled, multicenter study, researchers measured HRQL in 553 patients with moderate-to-severe persistent asthma treated with one of five SYMBICORT therapies.

The patients were subjected to two inhalations with SYMBICORT in one pressurised meter-dose inhaler (pMDI) 160/4.5 micrograms (mcg); budesonide pMDI 160 mcg; formoterol via dry-powder inhaler (DPI) 4.5 mcg; budesonide pMDI 160 mcg + formoterol DPI 4.5 mcg in separate inhalers; or placebo, each bid.

HRQL was assessed using the standardised Asthma Quality of Life Questionnaire [AQLQ(S)], a validated survey that measures how asthma affects a person's daily activities, emotional functioning, and symptoms and using patient and physician global assessments.

The study also measured satisfaction to treatment in 390 patients with mild-to-moderate asthma previously treated with inhaled corticosteroids. Patients were randomised to receive treatment with two inhalations with SYMBICORT 80/4.5 mcg, budesonide pMDI 80 mcg, formoterol DPI 4.5 mcg, or placebo, each bid.

Patient satisfaction was assessed using three indices of the Patient Satisfaction with Asthma Medication (PSAM) questi
'"/>




Page: 1 2
Related medicine news :

1. Drug Combo Works Better for children with ADHD, Tics
2. Scanning Combo Helps Detect Lung Cancer
3. Relief From Asthma With New Combo Therapy
4. Calcium-Vitamin D Combo For Reduced Fracture Risk
5. Drug Combo Improves Performance Of Multiple Sclerosis Drug
6. Alcohol-illusion: Alcohol and Energy Drinks Combo, Maintains Sobriety?
7. HER-2 Positive Breast Cancer Patients May Benefit With a Combo Drug Strategy
8. The Combo Treatment Is Effective to Treat Type 1 Diabetes in Mice
9. Doomed Duo: Obesity and Type 2 Diabetes Combo, Can Nip Life in the Bud
10. Arimidex-Herceptin Combo Therapy For Breast Cancer-Clinical Trial Findings
11. Fuzeon and MK-0518 Combo Holds Promise For HIV