Navigation Links
Combined Imaging Approach may Provide Better Identification of Difficult-to-diagnose Brain Clots

University of Cincinnati (UC) neuroradiologists believe a brain imaging approach that combines standard magnetic resonance imaging (MRI) scans with specialized// contrast-enhanced techniques could lead to more effective diagnoses in patients with difficult-to-detect blood clots in veins of the brain.

James Leach, MD, reports these findings in the April issue of the American Journal of Neuroradiology. This is the first study to correlate the clinical importance of data gleaned from standard MRI scans and detailed contrast-enhanced imaging techniques in patients with chronic thrombosis (blood clots) in veins of the brain.

"Detailed contrast-enhanced techniques produce more defined distinctions between abnormal and normal veins in the membrane around the brain," explains Leach, a neuroradiologist and associate professor at UC and principal investigator of the study. "Evaluating patients using a combination of imaging tools could give us a better understanding of the disease process."

Researchers say these specialized techniques—known as contrast-enhanced magnetic resonance venography—produce better defined pictures of difficult-to-detect abnormal flow areas within vessels of the brain. These areas may be important warning signs of blocked blood flow that require medical intervention. The enhanced imaging tools can also help identify areas where flow has been partially reestablished after a vessel blockage has occurred.

Leach and his team used these contrast-enhanced techniques, in combination with standard MRI scans, to evaluate a small subgroup of patients who have clinical and imaging features consistent with what is called partially recanalized chronic dural sinus thrombosis. This is a condition in the membrane surrounding the brain where blood flow has been partially reestablished in a previously blocked vessel.

Research has shown that cerebral veins partially or fully blocked by a blood clot—with or witho ut treatment—can open spontaneously, open partially or remain blocked. These blockages can stop blood flow to the brain and increase the patient’s risk for stroke and other neurological episodes such as chronic headache.

"In cases where the patient has an ongoing partial or full blockage," Leach explains, "the blood clot ‘organizes’ into a more solid lesion, forms connective scar tissue and can develop small vessels in an attempt to restore blood flow. This was very difficult to diagnose correctly using previous techniques."

"We don’t fully understand why this happens, but being able to recognize the imaging characteristics of the condition earlier may help us explain patient symptoms—like persistent headache—that otherwise cannot be explained," he adds.

With additional research, Leach believes, this combined imaging approach may one day help physicians formulate better treatment regimens and possibly prevent more serious medical complications for certain patients.

"If we can more easily characterize the patient’s problem as chronic instead of acute, it could alter the way we prescribe anticoagulation (clot-busting) drugs to treat the symptoms," says Leach. "Further research is needed to see if this can effectively impact patient therapy clinically."

Source-Eurekaler
MED/B
'"/>




Related medicine news :

1. Combined scan gives exact cancer diagnosis
2. A Protein-Rich Diet Combined With Exercise Found To Be More Effective In Weight Loss
3. Combined modality approach for effective treatment and enhanced survival in bile duct cancer
4. Vision Loss in Elderly Caused By Combined Effect of Genes and Bacterium
5. Exercise Combined with Dialysis Yields Better Results
6. Combined Anti-Fever Drug Therapy Proves Unsafe for Childhood Fever
7. A Combined Heart Pill-developed by Dr. Reddy’
8. A Combined Research for Producing Chlamydia Vaccine Begins
9. Combined Ingredients may Cut Cholesterol Levels
10. Combined Imaging Approach may Be Effective in Diagnosing Some Brain Clots
11. Imaging Modality That Might Help Diagnose Depression
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2017)... ... June 23, 2017 , ... 21 Middle East and ... has selected 21 leaders from government, business and civil society in 11 countries across ... U.S. this fall, engaging in a transformative exchange of knowledge and ideas with the ...
(Date:6/23/2017)... Jupiter, FL (PRWEB) , ... June 23, 2017 , ... ... the award winning series, which is slated to air fourth quarter 2017. American Farmer ... Christian D.A. Hansen, a Danish pharmacist, founded Chr. Hansen in Denmark in 1874 ...
(Date:6/23/2017)... ... June 23, 2017 , ... All-Star Insurance, a family managed agency that ... eastern Texas, is announcing the launch of a new charity drive to benefit women ... the United States reveal that an estimated 252, 710 new cases of invasive or ...
(Date:6/22/2017)... ... June 22, 2017 , ... Plastic Surgery Associates is proud to report that ... Each year, research and information firm, Castle Connolly, releases their list of the most ... marks the 3rd time that Dr. Canales has been recognized by Castle ...
(Date:6/22/2017)... ... 2017 , ... Despite its pervasiveness, many physicians are unfamiliar with how best ... with clinical practice. Now, however, a timely review has been published in the ... etiology of NeuP and educating preclinical scientists on its diagnosis and choice of treatment. ...
Breaking Medicine News(10 mins):
(Date:6/14/2017)... 14, 2017 The Bio Supply Management Alliance ... of Fremont and the Biomedical Manufacturing Network ... in California by providing a ... and fostering workforce development. The primary focus of this ... start-ups, as well as small and mid-sized biomedical companies. ...
(Date:6/12/2017)... SEATTLE , June 12, 2017 Kineta, Inc., ... today announced Kineta Vice President of R&D and ... at the Pandemic Preparedness for the Northwest and Beyond ... be held on June 14, 2017 from 8:30-10:30 AM PDT ... Dr. Bedard will be joined ...
(Date:6/9/2017)... 9, 2017 AirXpanders, Inc. (ASX: AXP) (AirXpanders ... design, manufacture, sale and distribution of the AeroForm® Tissue ... of its commercial roll-out in the United ... than one hundred (100) medical institutions and health systems, ... a needle-free alternative for women who choose reconstructive surgery ...
Breaking Medicine Technology: