Navigation Links
Combined Imaging Approach may Provide Better Identification of Difficult-to-diagnose Brain Clots

University of Cincinnati (UC) neuroradiologists believe a brain imaging approach that combines standard magnetic resonance imaging (MRI) scans with specialized// contrast-enhanced techniques could lead to more effective diagnoses in patients with difficult-to-detect blood clots in veins of the brain.

James Leach, MD, reports these findings in the April issue of the American Journal of Neuroradiology. This is the first study to correlate the clinical importance of data gleaned from standard MRI scans and detailed contrast-enhanced imaging techniques in patients with chronic thrombosis (blood clots) in veins of the brain.

"Detailed contrast-enhanced techniques produce more defined distinctions between abnormal and normal veins in the membrane around the brain," explains Leach, a neuroradiologist and associate professor at UC and principal investigator of the study. "Evaluating patients using a combination of imaging tools could give us a better understanding of the disease process."

Researchers say these specialized techniques—known as contrast-enhanced magnetic resonance venography—produce better defined pictures of difficult-to-detect abnormal flow areas within vessels of the brain. These areas may be important warning signs of blocked blood flow that require medical intervention. The enhanced imaging tools can also help identify areas where flow has been partially reestablished after a vessel blockage has occurred.

Leach and his team used these contrast-enhanced techniques, in combination with standard MRI scans, to evaluate a small subgroup of patients who have clinical and imaging features consistent with what is called partially recanalized chronic dural sinus thrombosis. This is a condition in the membrane surrounding the brain where blood flow has been partially reestablished in a previously blocked vessel.

Research has shown that cerebral veins partially or fully blocked by a blood clot—with or witho ut treatment—can open spontaneously, open partially or remain blocked. These blockages can stop blood flow to the brain and increase the patient’s risk for stroke and other neurological episodes such as chronic headache.

"In cases where the patient has an ongoing partial or full blockage," Leach explains, "the blood clot ‘organizes’ into a more solid lesion, forms connective scar tissue and can develop small vessels in an attempt to restore blood flow. This was very difficult to diagnose correctly using previous techniques."

"We don’t fully understand why this happens, but being able to recognize the imaging characteristics of the condition earlier may help us explain patient symptoms—like persistent headache—that otherwise cannot be explained," he adds.

With additional research, Leach believes, this combined imaging approach may one day help physicians formulate better treatment regimens and possibly prevent more serious medical complications for certain patients.

"If we can more easily characterize the patient’s problem as chronic instead of acute, it could alter the way we prescribe anticoagulation (clot-busting) drugs to treat the symptoms," says Leach. "Further research is needed to see if this can effectively impact patient therapy clinically."

Source-Eurekaler
MED/B
'"/>




Related medicine news :

1. Combined scan gives exact cancer diagnosis
2. A Protein-Rich Diet Combined With Exercise Found To Be More Effective In Weight Loss
3. Combined modality approach for effective treatment and enhanced survival in bile duct cancer
4. Vision Loss in Elderly Caused By Combined Effect of Genes and Bacterium
5. Exercise Combined with Dialysis Yields Better Results
6. Combined Anti-Fever Drug Therapy Proves Unsafe for Childhood Fever
7. A Combined Heart Pill-developed by Dr. Reddy’
8. A Combined Research for Producing Chlamydia Vaccine Begins
9. Combined Ingredients may Cut Cholesterol Levels
10. Combined Imaging Approach may Be Effective in Diagnosing Some Brain Clots
11. Imaging Modality That Might Help Diagnose Depression
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/17/2017)... ... ... Media, the industry leader in digital marketing for medical practices, has been recognized as one ... the Inc. 5000 for the second time in two years. Shawn Miele, Chief Executive Officer ... for the second year in a row. It’s extremely difficult to make this list once. ...
(Date:8/17/2017)... Yorba Linda, Ca (PRWEB) , ... August 17, 2017 , ... ... by the FDA to the biopharmaceutical industry in 2016 cited deficiencies in data integrity. ... their 21 CFR Part 11 ruling. , Presented as part of the ...
(Date:8/16/2017)... Kalamazoo, Michigan (PRWEB) , ... August 16, 2017 , ... ... Applications are now being accepted. , Students who successfully complete the seven-week long ... a Certified Nurse Assistant (CNA). The average starting salary for a CNA in Kalamazoo ...
(Date:8/16/2017)... (PRWEB) , ... August 16, 2017 , ... Greenfield Advisors ... companies in the U.S. for the second year in a row. The Inc. 5000 ... past three years. , “To be on the list once is a great accomplishment, ...
(Date:8/16/2017)... , ... August 16, 2017 , ... Any Lab ... 5000. The company ranked #4429 on the newly released, 36th annual Inc. 5000 ... a unique look at the most successful companies within the American economy’s most dynamic ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... 2017 Diplomat Pharmacy, Inc. (NYSE: DPLO ... as president, effective Aug. 7, 2017. ... pursue other interests and will serve as president emeritus during ... served us in multiple leadership roles since he joined Diplomat ... and has provided decisive, strategic leadership which continues to benefit ...
(Date:8/4/2017)... CINCINNATI , Aug. 3, 2017  Agragen, ... science company active in the biopharmaceutical, nutraceutical, and ... its development of its lead drug candidates, AGR131.  ... a proinflammatory cytokine from the blood of patients ... psoriasis, and inflammatory bowel disease. ...
(Date:8/2/2017)... 2017  Life Flight Network and PeaceHealth Oregon Network announced ... care and operational efficiency for patients at hospitals in ... Cottage Grove , and Florence, Oregon ... Life Flight Network work collaboratively to move patients who require ... a time sensitive emergency exists. ...
Breaking Medicine Technology: