Navigation Links
Combination growth factors for Stem cell proliferation

Professor Harvey Lodish and his post-doc Chengcheng Zhang from Whitehead Institute for Biomedical Research in Cambridge have found a combination of growth factors// which enriches and increases the number of stem cells in the laboratory before it could be injected into the recipient.

Stem cell therapy as shown that the quantity of stem cells required for a therapy is very high and it requires isolating large number of stem cells. Stem cells for therapeutic treatment are isolated from various sources like bone marrow, cord blood and peripheral blood but the quantity of isolated stem cells are very less.

Hematopoietic stem cells are required for production of billions of new blood cells and immune cells every day in our body as these cells have the capacity to give rise to different blood cells which protects the body from infection. Hematopoietic stem cells are used for treating various blood disorders and blood cancers.

The researchers combined the already well established growth factor IGF-2 with Angiopoietin-like 2 and -3 and found that the new combination increased the production of hematopoietic cell in the lab by more than 30 times. The researchers feel that increased production of stem cells would increase the transplantation rate and would also help in gene targeted therapy in which the gene of interest could be injected into the vector virus and these stem cells can be proliferated in the lab by using this combination growth factors and transferred to the recipient as the probability of gene transfer would be effectively increased. Though the combination growth factors have been very effective in proliferation in the laboratory conditions the researchers have to see the effect of this proliferation in humans. The result of the work has been published in the Journal Nature Medicine.

Page: 1

Related medicine news :

1. Consensus on "Combination Therapy" for Breast Cancer
2. Drug Combinations May Boost Stroke Risk
3. Combination therapy to treat breast cancer
4. Combination regime may work against prostate cancer
5. Smoking and Breast Cancer - A Deadly Combination
6. New Drug Combination Found To Improve Memory in Alzheimer’s Patient
7. A Combination Of Drugs Effective In The Treatment Of Hormone-Refractory Prostate Cancer
8. Combination Therapy Effective In Improving Lung Cancer Survival
9. Combination Therapy Found To Improves Stroke Recovery
10. Combination Therapy Found To Be More Effective In Treating Brain Cancer
11. Combination of Clopidogrel-aspirin is better for preventing stroke than only aspirin
Post Your Comments:

(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , ... Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , ... our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First ...
(Date:6/25/2016)... , ... June 25, 2016 , ... Conventional wisdom preaches ... success. In terms of the latter, setting the bar too high can result in ... than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... ... ... in a crisis. Her son James, eight, was out of control. Prone to extreme mood ... something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a ... children and say he was going to kill them. If we were driving on ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San ... Society and the Road To Recovery® program to drive cancer patients to and from ... adults to ensure the highest quality of life and ongoing independence. Getting to ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute Beauty Network, affiliated ... Weintraub as a prominent plastic surgeon and the network’s newest partner. , ... most handsome men, look naturally attractive. Plastic surgery should be invisible.” He stands ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Any dentist who has made an implant ... process. Many of them do not even offer this as ... high laboratory costs involved. And those who ARE able to ... a high cost that the majority of today,s patients would ... Parsa Zadeh , founder of Dental Evolutions Inc. and inventor ...
(Date:6/23/2016)... LOS ANGELES , June 23, 2016 /PRNewswire/ ... (NASDAQ: CAPR ), a biotechnology company ... first-in-class therapeutics, today announced that patient enrollment in ... progrEssion in Duchenne) has exceeded 50% of its ... its enrollment in the third quarter of 2016, ...
(Date:6/23/2016)... the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered in Bogota. Colombia ... ... Sandra ... ... Astellas is a pharmaceutical company ...
Breaking Medicine Technology: