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Combination Therapy Effective In Improving Lung Cancer Survival

Researchers from Japan say that the combination of chemotherapy with a new medication could improve survival among lung cancer patients.//

In the study of close to 1,000 patients, the overall survival rate was significantly higher in patients who received chemotherapy and the oral drug uracil-tegafur. Results of the study show 65 patients who received the combined therapy died within five years compared to 89 patients who received no therapy.

Researchers also found a recurrence or second primary cancer in 23 percent of the treatment group and 26 percent of the non-treatment group. Of the 482 patients who received treatment, only 10 patients experienced toxicity problems. Treatment was stopped if patients experienced a grade 3 level of toxicity.

However specialists say that though the study provides compelling evidence that uracil-tegafur can improve survival for stage I lung cancer patients , the drug has still not been approved in the United States, Thus limiting its use only to trials.
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