Navigation Links
Cocoa Polyphenols may Offer Diabetes Benefits - Study

Dietary supplementation with cacao liquor proanthocyanidins (CLPr) reduced blood glucose levels in obese diabetic mice, and may offer human diabetics// significant benefits, says a new study from Japan.

"Dietary supplementation with CLPr can dose-dependently prevent the development of hyperglycaemia in diabetic obese mice," wrote lead author Makoto Tomaru in the journal Nutrition. "The dietary intake of food or drinks produced from cacao beans might be beneficial in preventing the onset of type-2 diabetes mellitus."

An estimated 19 million people are affected by diabetes in the EU 25, equal to four per cent of the total population. This figure is projected to increase to 26 million by 2030.

In the US, there are over 20 million people with diabetes, equal to seven per cent of the population. The total costs are thought to be as much as $132 billion, with $92 billion being direct costs from medication, according to 2002 American Diabetes Association figures.

The potential health benefits of cocoa have been gaining increasing interest, with studies reporting that flavonoid-rich chocolate may reduce the risk of cardiovascular disease. However, according to Tomaru and co-workers, this is the first study to report that CLPr can prevent aggravation of type-2 diabetes mellitus.

The new study used three-week old female mice and randomly assigned them to eat the AIN-93 diet supplemented with 0, 0.5, or 1.0 per cent for cacao liquor proanthocyanidins (72 per cent total polyphenols) for three weeks.

At the end of the study the researchers report that the proanthocyanidins reduced blood glucose levels in a dose-dependent manner. Indeed, blood glucose levels after four and five weeks of age, and of fructosamine at six weeks of age were significantly lower than in those fed 0 per cent CLPr AIN-93 diet.

Body weights and food consumption did not differ significantly among the groups, said the resea rchers.

"In this study, the decreased levels of blood glucose may be involved in improvement of insulin resistance by antioxidative effects of CLPr," they said.

The one per cent dose used in this study would be equivalent to a daily polyphenol intake of five grams for a human, said Tomaru, or about 2.5 kg of normal chocolate. However, studies using flavonol-rich dark chocolate have reported positive effects with intakes of only 100 g of dark chocolate per day, providing a flavonol dose of 88 mg.

"On the basis of the previous report and the present results, chocolate, cocoa, and other functional foods that contain more CLPr may be recommended to obtain the benefits of cacao proanthocyanidins," concluded the researchers.

Further research is needed to investigate if such results can be repeated in humans, and what mechanism is responsible for these apparent benefits.

Source-Bio-Bio Technology

Related medicine news :

1. Yet Another Use For Cocoa Flavonols
2. Cocoa: Doesn’t Taste Like Red Wine But Has Benefits Like It
3. Cocoa Treats: Chocolates, as a Health Investment? Chew on this!
4. Cocoaphillic: so go and indulge as it is beneficial in heart disease.
5. Cocoa good for skin?
6. Cocoa Has The Ability To Improve Blood Circulation
7. Cocoa Rich In Flavonol Improves Blood Vessel Function In Elderly
8. New Study Suggests Special Cocoa may Lead to Sustained Improvement in Blood Vessel Function
9. Health Benefits Of Cocoa
10. Blood Pressure Tackled Better With Cocoa Than Tea
11. Polyphenols in Green Tea Cause Liver Damage At High Doses
Post Your Comments:

(Date:11/30/2015)... ... 30, 2015 , ... According to research by the National ... technicians to be certified or obtain continuing education. To increase awareness of the ... Mouth?” campaign to inform dentists that the technicians they trust could lack the ...
(Date:11/30/2015)... MN (PRWEB) , ... November 30, 2015 , ... ... at . The directory is specialized and only includes chiropractic clinics ... to find a competent and trustworthy alternative health practitioner when back pain sets ...
(Date:11/30/2015)... ... November 30, 2015 , ... The ... this summer, ushering in a new era of publicly accessible automated technology. Now, ... will continue to offer guests an up-close look at the shuttle at MOSI’s ...
(Date:11/30/2015)... Flint, Michigan (PRWEB) , ... November 30, 2015 ... ... a safe and fun atmosphere for Halloween festivities, the Word of Life Christian ... classic children’s board game, and featuring a giant 1.25 ton pile of candy ...
(Date:11/30/2015)... Alexandria, VA (PRWEB) , ... November 30, 2015 ... ... the mesothelioma-affected community across the United States to access life-saving information ... on Malignant Mesothelioma will consist of three individual conferences in three major ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... Nov. 30, 2015 Baxalta Incorporated ... leader dedicated to delivering transformative therapies to ... conditions, today announced the launch and first ... an extended circulating half-life recombinant factor VIII ... full-length ADVATE [Antihemophilic Factor (Recombinant)]. The treatment ...
(Date:11/30/2015)... --> --> According to ... (Soft Tissue, All Tissue, Dental Welding Lasers), Application (Conservative Dentistry, ... Global Forecast to 2020", published by MarketsandMarkets, is expected to ... 5.2% during the forecast period from 2015 to 2020. ... spread through 167 P ages and in-depth TOC on ...
(Date:11/30/2015)... Oramed Pharmaceuticals Inc. (NASDAQ: ORMP ), a clinical-stage ... delivery systems, announced today it has signed definitive licensing ... of Technologies Co., Ltd. ("HTIT") for exclusive rights to ... China , Hong Kong ... signed at the Israel Knesset (Parliament). ...
Breaking Medicine Technology: