Navigation Links
Clues to the Mystery of Lou Gehrig's Disease

entia and motor neuron disease. Clinically there's overlap in these two disorders, so it was very tantalizing to see if there was anything to link them biochemically."

The researchers developed monoclonal antibodies to TDP-43, and tested them in 72 post-mortem tissue samples patients with either ALS or frontotemporal lobar degeneration and found that all 72 cases contained misfolded TDP-43. Dr Lee said, "Since many cases were studied, the data became very compelling."

According to study co-author John Trojanowksi, M.D., Ph.D., director of Penn's Institute on Aging although ALS is well-known because of its link with Gehrig, frontotemporal lobar degeneration is less well-known while this may be because of its rarity in spite of it being the second most common cause -- after Alzheimer's disease -- of dementia in people under the age of 65.

Dr. Trojanowksi said, "Another reason for (its) relative obscurity is also undoubtedly the shame family members experience with the strange and, at times, bizarre behavior of patients, including disturbing obsessions, larceny, or even sexual deviancy, that may bring the patient to the attention of the legal system rather than to the healthcare system."

Dr Lee pointed out that usefulness of the finding depends on whether future research shows that TDP-43 is a useful target for new therapies and diagnostic tools.
NLA
'"/>




Page: 1 2

Related medicine news :

1. Innovative yeast genome may handle Cancer Clues
2. Researchers Discover New Clues To Identify Tooth Decay
3. Leeches Provide Clues Regarding The Prevention Of Heart Disease
4. Excavations Reveal Clues Of Early Warfare
5. Sleeping Computers Yield Clues About Genetic Disorders
6. Clues To Identify Psychological Seizures
7. A Human Brain Gene Could Hold Clues On The Evolution Of Brain Capacity
8. Clues Found On How Deadly Bacterium Gains Foothold
9. Clues to Allay Aging
10. Regrowth of Zebrafishs Tail Fin may Offer Clues for Treating Human Injuries
11. Renegade RNA: Clues to Cancer and Normal Growth
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Clues the Mystery Lou Gehrig Disease

(Date:9/21/2014)... September 22, 2014 The asthma ... decade, as it has become saturated with relatively ... inhaled corticosteroids (ICSs), inhaled corticosteroids and long-acting beta-agonists ... facing increasing generic competition. However, the launch of ... and ICS/LABA therapies delivered by the next-generation inhalers ...
(Date:9/21/2014)... The Electronic Medical Records Systems ... medical records (EMR) and electronic health records (EHR) ... during the past five years and is expected ... years to 2019. The 2009 Health Information Technology ... and Medicaid incentives to encourage the widespread adoption ...
(Date:9/21/2014)... September 21, 2014 Market ... (CAS 49562-28-9) Industry, 2009-2019 is a professional ... Chinese Fenofibrate (CAS 49562-28-9) industry. The report ... (CAS 49562-28-9) including its classification, application and ... China’s top manufacturers of Fenofibrate (CAS 49562-28-9) ...
(Date:9/21/2014)... 2014 “Cluster headaches are sometimes called ... difficult to resolve,” said Steve Young of Ew Publishing; ... a pain that is more intense.” , “It should ... headaches, or migraines, that medical research is pointing to ... he added. , Serotonin (5-HT, 5-hydroxytryptamine) is a ubiquitous ...
(Date:9/21/2014)... According to latest National Vital Statistics ... since 1966 (10.5 births per 1,000 women in 2013). Since ... risen steadily by 2 percent per year. The birth rate ... 50 and over) also rose, the first such increase since ... nine times as many first births to women aged 35 ...
Breaking Medicine News(10 mins):Health News:Spiriva Asthma Market (Tiotropium Bromide) Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 2Health News:Spiriva Asthma Market (Tiotropium Bromide) Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 3Health News:Spiriva Asthma Market (Tiotropium Bromide) Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 4Health News:Electronic Medical Records Systems in the US Industry Market Research Report Now Available from IBISWorld 2Health News:Electronic Medical Records Systems in the US Industry Market Research Report Now Available from IBISWorld 3Health News:Electronic Medical Records Systems in the US Industry Market Research Report Now Available from IBISWorld 4Health News:Fenofibrate Industry Global and Chinese Analysis for 2014-2019 Now Available at LifeScienceIndustryResearch.com 2Health News:Fenofibrate Industry Global and Chinese Analysis for 2014-2019 Now Available at LifeScienceIndustryResearch.com 3Health News:Fenofibrate Industry Global and Chinese Analysis for 2014-2019 Now Available at LifeScienceIndustryResearch.com 4Health News:Homeostasis: Equinox Serotonin (5HT) Headache Stories ~ New on the Bryan William Brickner Blog 2Health News:Statistics Reveal That the Number of 'Older' First-Time Mothers Is Growing 2Health News:Statistics Reveal That the Number of 'Older' First-Time Mothers Is Growing 3Health News:Statistics Reveal That the Number of 'Older' First-Time Mothers Is Growing 4
... News) -- The incidence of head and neck cancers related ... States, with the greatest increase among middle-aged white men, a ... risk factors for head and neck cancers, but the sexually ... well, according to researchers from the Louisiana State University Health ...
... Long-term follow-up of a phase II clinical trial ... non-small cell lung cancer treated with belagenpumatucel-L, a therapeutic ... Annual Meeting 2012, held March 31 - April 4. ... to show unusually long survival in some patients," said ...
... Awakening from anesthesia is often associated with an ... restoration of awareness and orientation to one,s surroundings. ... consciousness emerges first. Using brain imaging techniques in ... Adjunct Professor Harry Scheinin, M.D. from the University ...
... (Boston) - Anurag Singh, PhD, assistant professor in ... Boston University School of Medicine has been invited ... for colon cancer at the American Association of ... Singh,s seminar, scheduled for Tuesday April 3rd, will ...
... , TUESDAY, April 3 (HealthDay News) -- Weight ... girls, self-esteem, according to a new study. "We found ... of obesity continued to see themselves as fat, despite changes ... associate professor of sociology at Purdue University in West Lafayette, ...
... Removing a lipoprotein receptor known as SR-BI may help ... presented at the American Association for Cancer Research Annual ... In vitro and mouse studies revealed that depletion of ... cell growth. SR-BI is a receptor for high-density ...
Cached Medicine News:Health News:HPV-Related Head, Neck Cancers on the Rise 2Health News:Scientists solving the mystery of human consciousness 2Health News:Scientists solving the mystery of human consciousness 3Health News:For Many Girls, Slimming Down Doesn't Help Self-Esteem 2Health News:Eliminating the 'good cholesterol' receptor may fight breast cancer 2
(Date:9/19/2014)... Mass. , Sept. 19, 2014  Alere Inc. ... rapid diagnostics, issued the following statement today in support ... Antibiotic-Resistant Bacteria. "As the global leader in ... for establishing a national strategy to address the serious ... to work with the Administration on initiatives to promote ...
(Date:9/19/2014)... MINNEAPOLIS and ORLANDO, Fla. ... data supporting Inspire therapy continues to grow, with the ... paper published on-line in Otolaryngology – Head ... therapy causes a worsening of both objective and subjective ... to directly attribute Inspire therapy for the reduction in ...
(Date:9/19/2014)... , Sept. 19, 2014  CytRx Corporation (Nasdaq: ... specializing in oncology, today announced that David J. ... BioCentury,s 2014 NewsMakers in the Biotech Industry Conference on Friday, ... The conference will take place at the Millennium Broadway ... A live and archived webcast of the ...
Breaking Medicine Technology:Alere Applauds President's Executive Order Combating Antibiotic-Resistant Bacteria 2New Data shows Reductions in obstructive sleep apnea (OSA) severity and improvement of quality of life with Inspire therapy 2New Data shows Reductions in obstructive sleep apnea (OSA) severity and improvement of quality of life with Inspire therapy 3New Data shows Reductions in obstructive sleep apnea (OSA) severity and improvement of quality of life with Inspire therapy 4CytRx to Present at BioCentury's 2014 NewsMakers in the Biotech Industry Conference 2CytRx to Present at BioCentury's 2014 NewsMakers in the Biotech Industry Conference 3
... services for Cordex,s ATPace arrhythmia drug to be provided ... Pharma, Inc. (OTC Bulletin Board: CDXP) announced today that ... equity agreement with Cato BioVentures. As part of this ... arrange for Cato Research to perform regulatory services and ...
... be useful in treatment for degenerative disc disease LAS VEGAS, ... disease, sends millions of people to their doctor. In fact, ... do so because of disc degeneration. And part of the ... In their quest to discover ways to stop or reverse ...
Cached Medicine Technology:Cordex Pharma Announces Strategic Master Services Equity Agreement With Cato BioVentures 2Cordex Pharma Announces Strategic Master Services Equity Agreement With Cato BioVentures 3Cordex Pharma Announces Strategic Master Services Equity Agreement With Cato BioVentures 4Cordex Pharma Announces Strategic Master Services Equity Agreement With Cato BioVentures 5Cordex Pharma Announces Strategic Master Services Equity Agreement With Cato BioVentures 6Aching Back? Cholesterol Medication Might Help 2Aching Back? Cholesterol Medication Might Help 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: