Navigation Links
Clotting Protein plays a role in nerve repair

According to a new study, fibrin, a protein that helps form blood clots, may also be involved in regulating the repair of nerve damage. The discovery could lead to new strategies for repairing diseases of the nervous system, such as multiple sclerosis, although the research is still on the basic science level.//

In multiple sclerosis, the slow destruction of myelin--the thin, protective coating that insulates nerve fibers in the brain and spine can lead to numbness, muscle weakness and stiffness, impaired vision and coordination problems. In nerves outside the brain or spinal cord, loss of myelin can also occur after an injury.

Previous research has shown that fibrin gathers in the lesions of people with multiple sclerosis, but the protein's role in nerve repair has not been studied widely. Now Dr. Sidney Strickland and colleagues at Rockefeller University in New York report that fibrin seems to play a critical role in repairing damaged myelin. The researchers made the discovery by studying mice that lacked the protein. After an injury to the sciatic nerve (located in the leg), myelin regenerated much more rapidly in fibrin-free mice than in normal mice.

Strickland's team describes fibrin's role in the repair process--at least outside the brain and spinal cord. After a nerve injury, it seems that a protein called fibrinogen can leak from the blood into the damaged nerve. Once in the nerve, fibrinogen is converted into fibrin. While this is going on, myelin-repairing cells called Schwann cells begin proliferating. But the presence of fibrin keeps Schwann cells from beginning their repair job.

As fibrin is gradually dissolved, however, Schwann cells are able to begin repairing the damaged myelin and regenerating the myelin sheath as the nerve grows. Schwann cells help repair nerves outside of the brain and spinal cord, while a second type of cell has at least "limited capacity" to repair myelin in the brain.

A
'"/>




Page: 1 2

Related medicine news :

1. FDA Approves New Anti-Clotting Drug
2. Blood Clotting Protein Discovered
3. Blood Clotting Disorders Linked To Three Proteins
4. Scientist Discovers Crucial Part of Blood-Clotting Process
5. Predicting the Dynamics of Clotting in Human Blood
6. New Anti-Clotting Drug Less Risky For Heart Attack Patients
7. Lean Protein Could Be Key to Obesity Drugs
8. Evidence Links Protein Damage to Neurodegenerative diseases like Parkinsons and Alzheimers
9. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
10. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese
11. Protein in urine foresees heart disease
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Clotting Protein plays role nerve repair

(Date:12/25/2014)... Dennis Thompson HealthDay ... Very sick children with complex chronic illnesses can receive effective, ... "medical home," with easy access to a team of dedicated ... less likely to become seriously ill and need either hospitalization ... treatment at an enhanced medical home clinic at the University ...
(Date:12/25/2014)... common during the holidays, but there are strategies that can ... arrive at a party hungry. It may seem logical to ... party, but deprivation leads to hunger, and hunger leads to ... Mount Kisco, N.Y., said in a hospital news release. ... to have a snack before attending a party when you ...
(Date:12/25/2014)... By Dennis Thompson ... -- Researchers could be closing in on a "fountain of ... improve the health of older adults, a new study suggests. ... when given a drug that targets a genetic signaling pathway ... maker Novartis report. The experimental medication, a ...
(Date:12/25/2014)... New York (PRWEB) December 25, 2014 ... continue to move forward in a number of multidistrict ... of West Virginia, Bernstein Liebhard LLP reports. According to ... is scheduled to convene a Joint Status Conference in ... 10:00 a.m. Parties have been directed to submit a ...
(Date:12/25/2014)... 2014 Plugin creators from Pixel Film ... fully customizable business presentation tool made specifically for ... 5k business tool, users can now display their stats ... Pixel Film Studios. “ProFire 5k gives users a multiple ... professionalism to a presentation” , Pixel Film Studios takes ...
Breaking Medicine News(10 mins):Health News:Coordinated Care Through 'Medical Home' Best for Chronically Ill Kids: Study 2Health News:Coordinated Care Through 'Medical Home' Best for Chronically Ill Kids: Study 3Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 2Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 3Health News:Federal Court Overseeing Thousands of Transvaginal Mesh Lawsuits Set to Convene Joint Status Conference for All Litigations, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing Thousands of Transvaginal Mesh Lawsuits Set to Convene Joint Status Conference for All Litigations, Bernstein Liebhard LLP Reports 3Health News:Federal Court Overseeing Thousands of Transvaginal Mesh Lawsuits Set to Convene Joint Status Conference for All Litigations, Bernstein Liebhard LLP Reports 4Health News:Announcing a new ProFire 5k plugin from Pixel Film Studios for Final Cut Pro X Professionals 2
... Responding to raging,wildfires is not the only challenge ... According to THE RIPON FORUM, California,s Governor is ... health care system and,provide universal coverage to the ... edition, the FORUM focuses on Schwarzenegger,s efforts in,this ...
... American Red Cross,Blood Services national system continues to aid ... from across the United States to,help stabilize the local ... due to the wildfire situation, and as a result,donations ... American Red Cross nationally has provided nearly 2,000 blood,products ...
... Oct. 26 Paramount Acquisition Corp.,(OTC Bulletin Board: PMQC, ... of 100% of the outstanding stock of B.J.K.,Inc., a ... Rx"),pursuant to a Stock Purchase Agreement, by and among ... June 1, 2007, as amended. Effective as,of the closing ...
... by Robert S. Kunkel, M.D., CLEVELAND, ... headache," and you,don,t have to take it ... publishing arm of Cleveland Clinic,( http://www.clevelandclinic.org/ ), ... Dr. Robert S. Kunkel, one of America,s ...
... a statewide,effort to help provide basic comforts to ... State Medical Society (MSMS),Foundation mobilized hundreds of volunteers ... in conjunction with the Gannett,Foundation/Points of Light Foundation,s ... "The women and children in Michigan,s domestic ...
... Uchida to join the Company, NATICK, Mass., ... Dawkins, M.D., and Takahiro Uchida, M.D., will,be joining ... will serve as Senior Vice President and Associate ... team and the,Company,s Operating Committee. He is an ...
Cached Medicine News:Health News:Latest Edition of Ripon Forum Highlights Schwarzenegger's Leadership on Another Challenge Facing his State - Health Care 2Health News:American Red Cross Blood Services Supports the Blood Needs of Southern California 2Health News:Paramount Completes Acquisition of Chem Rx 2Health News:Cleveland Clinic Press Releases Consumer Health Book About Treating Headache Pain 2Health News:Michigan State Medical Society Foundation 'Makes A Difference' by Assisting Those in Crisis Shelters 2Health News:Boston Scientific Announces Additions to Clinical Sciences Organization 2Health News:Boston Scientific Announces Additions to Clinical Sciences Organization 3Health News:Boston Scientific Announces Additions to Clinical Sciences Organization 4
(Date:12/24/2014)... DIEGO , Dec. 24, 2014  Conkwest, ... West, developing the proprietary Natural Killer (NK) cell-line ... that Dr. Patrick Soon-Shiong , NantWorks founder, ... a definitive agreement to purchase approximately $48 million ... connection with the investment, he will be named ...
(Date:12/24/2014)... PuraMed BioScience®, Inc., (OTC Pink: PMBS), a ... healthcare products, announced it received the initial funding to ... headache relief product, for planned distribution to 1,000 medical ... , Washington State , and ... H Advanced headache relief gel formulation completed, PuraMed BioScience ...
(Date:12/24/2014)... December 24, 2014 ... Global Disposable Syringe Industry of 178 pages ... business intelligence library. The 2014 ... Industry is a professional and deep research ... overview analysis, the report introduces Disposable Syringe ...
Breaking Medicine Technology:Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 2Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 3Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 4Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 5PuraMed BioScience Nears Final Stages Needed for Distribution of MigraPure H 2PuraMed BioScience Nears Final Stages Needed for Distribution of MigraPure H 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 2World Disposable Syringe Market 2014 Report: China and Regional Analysis 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 4World Disposable Syringe Market 2014 Report: China and Regional Analysis 5
... PLANO, Texas, Dec. 1, 2011 /PRNewswire-iReach/ -- ... medical real estate development and medical investment solutions is ... Pedro Vergne-Marini, MD to its publication, "350 People in ... leaders who shape the ambulatory surgery center industry through ...
... Dec. 1, 2011 Hologic, Inc. (NASDAQ: HOLX ... Chief Financial Officer, will be presenting at the Nasdaq OMX ... at 11:15am (GMT). Interested parties are invited to ... on the investor section of Hologic,s website at www.hologic.com/investors-overview ...
Cached Medicine Technology:Physicians' Capital Investments Announces Pedro Vergne-Marini, MD Named to Becker's ASC Review "350 People in the ASC Industry to Know" 2Physicians' Capital Investments Announces Pedro Vergne-Marini, MD Named to Becker's ASC Review "350 People in the ASC Industry to Know" 3Physicians' Capital Investments Announces Pedro Vergne-Marini, MD Named to Becker's ASC Review "350 People in the ASC Industry to Know" 4
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: