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Circumcision Studies to Continue Says Health Panel

cision is not a traditional practice. Half have subsequently been circumcised, and the others have their foreskins intact. The trial is scheduled to end by September 2007, at which time researchers will tally up any HIV-positive and HIV-negative in both groups.

Researchers at Johns Hopkins University and Columbia are leading the Rakai study, which is slated for completion in July 2007 and has enrolled 5,000 men.

Auvert's study in South Africa was stopped because early view at the data showed 49 of the uncircumcised men had become HIV-positive, compared with 20 in the circumcised group. That showed a protective effect of 60 percent, and further analysis of the data suggests it might be as high as 76 percent.

Dr. John Krieger, a University of Washington urologist who has been tracking the safety of the Kenyan trial, said he is not concerned about the failure to end the study early which actually was designed from the start to go on until next year.


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