Navigation Links
Circumcision Studies to Continue Says Health Panel

AIDS-prevention experts have had their hopes dashed after National Institutes of Health panel ruled that there was not need to stop the two ongoing studies of male //circumcision as a method of reducing risk of HIV infection.

Last year a South African medical committee halted a circumcision study after an early look at the data, which showed that circumcision reduced risk of HIV infection by at least 60 percent. Scientists finding that the protective effect was so beneficial, believed that it would be unethical to continue the experiment and withhold the findings.

French researcher Bertran Auvert and colleagues in Johannesburg and France conducted the South African study. 3,274 men participated as subjects for the study. Its results were published in January in the journal PLoS Medicine.

The NIH committee monitoring similar studies in Rakai, Uganda and Kisumu ,Kenya took a preliminary look at results of those two experiments on Tuesday and ruled that they should continue until the scheduled completion time next year.

The decision has however ensured that there will be no early release of the data for discussion at the 16th International AIDS Conference this August in Toronto, which otherwise would have led to circumcision being the big news of the global AIDS meeting.

According to Robert Bailey, the University of Illinois epidemiologist who is lead investigator of the Kenyan study, ‘It doesn't mean we don't have a 60 percent figure, or better.’ The interim results remain a secret, even to the investigators involved, because the trial is known as "blinded." This is to ensure the scientific integrity of the eventual findings.

Bailey also mentioned that there was a possibility that the monitoring board would look at the data once again in six to eight months to determine whether an early halt to the experiment was warranted.

The study involved 3,000 previously uncircumcised men in Kisumu where circum cision is not a traditional practice. Half have subsequently been circumcised, and the others have their foreskins intact. The trial is scheduled to end by September 2007, at which time researchers will tally up any HIV-positive and HIV-negative in both groups.

Researchers at Johns Hopkins University and Columbia are leading the Rakai study, which is slated for completion in July 2007 and has enrolled 5,000 men.

Auvert's study in South Africa was stopped because early view at the data showed 49 of the uncircumcised men had become HIV-positive, compared with 20 in the circumcised group. That showed a protective effect of 60 percent, and further analysis of the data suggests it might be as high as 76 percent.

Dr. John Krieger, a University of Washington urologist who has been tracking the safety of the Kenyan trial, said he is not concerned about the failure to end the study early which actually was designed from the start to go on until next year.


'"/>




Related medicine news :

1. Circumcision Found To Prevent HIV Spread
2. Circumcision More Effective In Reducing The Risk Of HIV Protection
3. Circumcision Ritual May Protect Men From AIDS
4. More News That Circumcision Could Reduce risk of HIV infection
5. Men queue up for Circumcision In Swaziland To Prevent HIV/AIDS
6. Circumcision, Will Have To Wait
7. High Demand For Circumcision In AIDS-Hit Swaziland
8. Female Circumcision Rampant in Africa
9. Practise Of Male Circumcision In Africa May Reduce HIV Risks
10. Circumcision to Avert HIV Infection
11. Pain Relief During Circumcision
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/17/2017)... ... August 17, 2017 , ... CareAcademy, ... that it has raised $1.675 M in seed funding to further expand its ... and Techstars Venture Capital Fund are the company’s primary investors. , ...
(Date:8/17/2017)... ... , ... Centrifugation is more than just spinning. Like a car in our ... do without. And just like a car, there are a few points to consider ... will learn about the most important safety aspects while using a centrifuge, as well ...
(Date:8/16/2017)... ... , ... The next Patient Care Academy at Kalamazoo Valley Community College begins ... the seven-week long Patient Care Academy are eligible to take the State of Michigan ... CNA in Kalamazoo is $24,428.* , As a CNA, one is equipped for employment ...
(Date:8/16/2017)... ... August 16, 2017 , ... The Data Council, the leading ... was acquired by Advantage Solutions. The Data Council’s IX-ONE platform is the ... industry’s leading suppliers, brokers, distributors and retailers. The Data Council will become a ...
(Date:8/16/2017)... ... August 16, 2017 , ... QualDerm Partners , ... development, today announced Cumberland Skin Surgery and Dermatology has joined the ... offices in both Hermitage and Lebanon, Tennessee, provides comprehensive general dermatology and skin ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... GAITHERSBURG, Md. , Aug. 7, 2017 /PRNewswire/ ... for healthcare member acquisition, retention, and engagement, announced ... Director of Strategy and Product Development, effective as ... strategic consulting and technology implementation strategy for our ... years of experience in consulting and business analytics ...
(Date:8/7/2017)... 7, 2017  Endo International plc (NASDAQ: ... resolve virtually all known U.S. mesh product liability claims ... the known remaining U.S. claims at reasonable values. Under ... the fourth quarter of 2017 and continuing through the ... quarter 2017 results, the Company intends to increase its ...
(Date:8/2/2017)... , Aug. 2, 2017 Fenita ... Who as a Pinnacle Lifetime Professional in the ... Account Manager at Turing Pharmaceuticals, AG. Her skills ... and relationship building.                ... than 25 years of experience as a highly ...
Breaking Medicine Technology: