Navigation Links
Cigarette Smoking and High Body Mass Index Increase the Risk of AMD

Researchers have found that contacting with Age-related Macular Degeneration (AMD) is higher among the people who smoke and whose Body Mass Index is 30 or higher//.

Current cigarette smoking was associated with a fivefold increased risk and high BMI (30 or higher) was associated with a twofold higher risk of AMD. The homozygous risk genotype (CC) plus smoking conferred a tenfold higher risk of AMD, compared with non-smokers with the non-risk (TT) genotype, while the risk genotype plus higher BMI increased risk of AMD almost sixfold.

Subjects in this study were Caucasians who had either advanced AMD (574 people) or no evidence of AMD (280 individuals), based on ocular examination and ocular photographs. DNA samples were obtained from the genetic repository of the Age-Related Eye Disease Study, a National Institutes of Health (NIH) clinical trial for which Johanna M. Seddon, M.D., director of the Epidemiology Unit at MEEI and an associate professor of ophthalmology at Harvard Medical School, was clinic director at MEEI. DNA samples were genotyped at the Broad Institute Center for Genotyping and Analysis, Boston, Mass. and statistical analyses were done in the Epidemiology Unit at MEEI.

“These findings convey an important message. Although we cannot change our genotype, we can alter or modify our risk of getting AMD by controlling our weight and not smoking,” said Dr. Seddon. “There is no question that genetic factors play an important role in this disease. However, individuals with the risk genotype may be more motivated to adhere to healthy lifestyles such as not smoking, maintaining a normal weight, getting exercise, eating an antioxidant rich diet, as well as fish, and getting exercise.”

AMD is the leading cause of irreversible visual impairment and blindness among persons aged 60 and older. With the elderly population steadily growing, the burden related to this loss of visual function will increase. Limited treatmen t options exist for the late stages of the disease and prevention remains a promising approach for addressing this public health concern.

(Source: IAN)
'"/>




Related medicine news :

1. Cancers of Colon & Rectum linked to Cigarette Smoking
2. Low-Tar Cigarettes As dangerous As High-Tar Cigarettes
3. Reducing Number Of Cigarettes Not Enough
4. The Harmful Effects Of Cigarette Smoke
5. Dangers Of Cigarette Smoke
6. Genes Linked To Cigarette Addiction
7. Light Cigarettes - Not So Light?
8. Cigarette Smoking Leads To Development Of Type 2 Diabetes In Patients With Coronary Artery Disease
9. Passive Cigarette Smoking Increases Isoprostane Formation
10. British company developing ‘Safer Cigarettes
11. Anti-smoking advertisements to be funded by Cigarette manufacturers
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... People across ... in Genome magazine’s Code Talker Award, an essay contest in which patients and their ... award to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual ...
(Date:6/24/2016)... New York, NY (PRWEB) , ... June 24, ... ... lifestyle publication Haute Living, is proud to recognize Dr. Barry M. Weintraub as ... believes that “the most beautiful women in the world, and the most handsome ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic ... Frederick area economy by obtaining investment capital for emerging technology companies. SCP ... that have already resulted in more than a million dollars of capital investment ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Venture ... Golf Classic Tournament held on June 20th at the Woodmont Country Club at ... Luke’s Wings, an organization dedicated to helping service members that have been wounded in ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... upcoming 2016 Miss Arizona pageant as its official Medspa Sponsor. Dr. Josh Olson, ... and Chandler, Arizona. , Dr. Olson says the decision to support the ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 26, 2016 ... care operating models within the health care industry is ... financial efficiency , Deloitte offers a suite of ... business issues impacting efficient cost optimization: labor resource analysis, ... These services facilitate better outcomes and better economics ...
(Date:6/24/2016)... CAMBRIDGE, Mass. , June 24, 2016 /PRNewswire/ ... the Spaulding Rehabilitation Network,s Dean Center for ... of Physical Medicine and Rehabilitation, MIT Hacking Medicine, ... Center for Innovation, today announced the five finalists ... Hackathon for Lyme disease.  More than 100 scientists, ...
(Date:6/24/2016)... Dehaier Medical Systems Ltd. (NASDAQ: ... and sells medical devices and wearable sleep respiratory products ... cooperation agreement with Hongyuan Supply Chain Management Co., Ltd. ... 20, 2016, to develop Dehaier,s new Internet medical technology ... will leverage Hongyuan Supply Chain,s sales platform to reach ...
Breaking Medicine Technology: