Navigation Links
Chronic Sinusitis May Be Related To Nasal Mucus

Researchers of Mayo Clinic have found the cause of chronic sinus infections is the direct// result of the nasal mucus getting infected and not the nasal and sinus tissue. The findings will be published in the August issue of Journal of Allergy and Clinical Immunology.

Researchers fro the study report that the age old belief that chronic sinus infection strikes the diseased airway tissue is not valid anymore, as their findings show that toxic protein are released into the mucus because of the infection. Therefore, scientists might need to take not only the tissue but also the mucus into account when trying to understand what causes chronic sinus infections and probably other airway diseases.

The findings could significantly change the way chronic sinus infection is treated, said the researchers.

The team found that, in chronic sinus infection patients, activated white blood cells (eosinophils) cluster in the nasal and sinus mucus and scatter a toxic protein (major basic protein) onto the nasal and sinus membrane. While major basic protein was not distributed in the nasal and sinus tissue, the level of this protein in the mucus of chronic sinus infection patients far exceeded that needed to damage the nasal and sinus membranes and make them more susceptible to infections such as chronic sinus infection.

To conduct this investigation, the researchers had collected specimens from 22 consecutive Mayo Clinic chronic sinus infection patients undergoing endoscopic sinus surgery. The surgeons extracted the maximum possible tissue and mucus during the sinus surgery. The surgeons also extracted tissue and mucus from healthy patients undergoing septoplasty, surgery to fix a deviated septum, for comparison with the specimens from the chronic sinus infection patients. Through various forms of laboratory examination of the tissue and attached mucus, the investigators observed an abundance of major basic protein throughout the nasal and sinus mucus in all 22 specimens, but not in the tissue.

The research suggests a beneficial effect in treatments that target primarily the underlying and presumably damage-inflicting nasal and sinus membrane inflammation, instead of the secondary bacterial infection that has been the primary target of treatments for the disease. Also, some surgeons have already started to change the way they do surgery for patients with chronic sinus infections, focusing now on removing the mucus, which is loaded with toxins from the inflammatory cells, rather than the tissue during surgery. Leaving the mucus behind might predispose patients for early recurrence of the chronic sinus infection, said the scientists.

Source: Newswise

Medindia on Chronic sinus infection: Further information

Chronic sinus infection: This is the condition of chronic or prolonged inflammation in the sinuses of the head. Chronic sinus infection is caused by allergies or infection by bacteria that can cause cold like symptoms and symptoms of upper respiratory tract infection. However the permanent damage of such an infection will be the damage or destructions of the tissue of the sinus.


'"/>




Related medicine news :

1. Roller coasters – cause “Chronic Headache?
2. In Chronic Diseases - Poor compliance of Patients with drug treatment
3. New Treatment for Chronic Eczema
4. Novel Therapy for Chronic Problem
5. Overcoming Chronic Fatigue
6. Chronic Fatigue, Pain Linked to Sinusitis
7. Chronic Diseases said to Cause Falls in the Elderly
8. Epilepsy Drug May Relieve Chronic Headaches
9. Women Worse Affected By Chronic Cough
10. A Drug That Might Relieve Chronic Cough
11. A Sedentary Childhood Could Lead To Chronic Fatigue Latter In Life
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/29/2016)... ... 2016 , ... In an article published April 16th on the ... and lip injections, which she underwent in order to feel more at home at ... Festival. The article explains that Ms. Mirmelli’s situation is not unique; many plastic surgeons ...
(Date:4/29/2016)... ... April 29, 2016 , ... ... Awakening , announces the addition Onnit brand Alpha BRAIN and New Mood Daily-Stress ... Onnit brain and mood optimization products to the store is just one more ...
(Date:4/29/2016)... Springs, California (PRWEB) , ... April 29, 2016 ... ... lies at the heart of our nation’s productivity, stability, even security. Most importantly, ... for their organizations. , Then why are American workers so unhappy? , Just ...
(Date:4/29/2016)... ... April 29, 2016 , ... Conditions were ideal for Global Lyme Alliance’s ... Sunday, with sunny skies, a light breeze and temperatures in the 60s. Over 400 ... 5k Run and Walk and 1-mile walk were held to increase awareness about ...
(Date:4/29/2016)... ... ... Spine Team Texas, a comprehensive spine physician group specializing in the treatment of ... invited to be a featured speaker at the Texas Society of the American College ... , Dr. R. Scott McPherson, a physical medicine and rehabilitation specialist, will speak ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... , April 28, 2016 ... consumer insights on healthcare, announced today that it has ... report Cool Vendor in Life Sciences, 2016, ... 15, 2016.  The report focuses on life-science- oriented analytics, ... insight from patients and doctors, confirm medication ingestion, and ...
(Date:4/28/2016)... , April 28, 2016  ValGenesis, Inc., ... Management Solutions (VLMS) today announced that a ... for sufferers of chronic kidney failure has ... manage their corporate validation process. The global ... software solution to manage their validation processes ...
(Date:4/27/2016)... , le 27 Avril 2016 ... a progressé de +5% sur le trimestre, soutenu ... de consommables  Croissance de +16% des ... Mauna Kea Technologies (Euronext : MKEA, FR0010609263 ; ... confocale laser, annonce aujourd,hui son chiffre d,affaires pour ...
Breaking Medicine Technology: