Navigation Links
Cholesterol and Insulin Secretion -bound by a Gene

Scientists have conducted a study, the first of its kind to link cholesterol with Type// 2 Diabetes.

The experiment was performed on mice, yet scientists say the findings may be applicable to humans too.

The cause for Type 2 diabetes is still unknown. There are varied theories on this. Yet one of the features of this disease is the reduction in production of insulin, by the beta cells of the pancreas.

The Canadian Diabetes Association estimates that more than 2 million Canadians have diabetes, of which 1.8 million have type 2. And the figures are rising.

In 2000 the World Health Organization (WHO) estimated that over 177 million people had diabetes worldwide and they say by 2025 the figure will be 300 million.

The scientists based at Canada’s Vancouver Child and Family Research Institute, in the online edition of Nature Medicine reveal study results that, when cholesterol levels in the pancreas go up, diabetes might be the outcome. This refers to the cholesterol in the pancreas.

Few might be aware that cholesterol is found in all cells and a normal amount is beneficial to the body as it aids in cell membrane function, meaning it regulates the materials entering and leaving a cell.

The presence of cholesterol in the pancreas and its high expression was brought to the lead author’s notice by one of his students, Dr. Liam Brunham .In response to that the researcher Dr. Michael Hayden, decided to experiment with the gene ABCA1.

Previous studies showed that the gene called ABCA1, was responsible for regulating cholesterol levels in cells.

When the scientists used genetically modified mice to switch off these genes, it was seen that obviously, the cholesterol levels in these cells began to get upset. They increased significantly and strangely, the rats began to show symptoms of diabetes like reduced levels of insulin and glucose intolerance. They went on to become fully diab etic.

On testing the pancreas cells of the mice in vitro they found high levels of cholesterol arising due to disturbance in cholesterol homeostasis.

The scientists,excited with this possible link between cholesterol and insulin secretion, now plan to extend these studies to humans too, hoping it may pave the way for a better understanding and prevention of Type 2 diabetes.
AN
'"/>




Related medicine news :

1. Low Cholesterol Linked to Severe Depression and Violent Behavior in Men
2. Eating More Often May Help Lower Cholesterol
3. Caution On Use of Cholesterol Drugs
4. High Cholesterol linked to Alzheimer’s diseas
5. Cholesterol Drug Helps After Angioplasty
6. Cholesterol lowering drugs increase neuropathy risk
7. Almonds Improve Cholesterol
8. Cholesterol-lowering therapy benefits older people also
9. Cholesterol lowering drugs aid people after heart transplant
10. New Cholesterol gene linked to Alzheimers
11. Children’s Cholesterol Matter
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... ... The American Board of Family Medicine's (ABFM) Board of Directors has selected ... Dr. James C. Puffer upon his retirement. Dr. Newton will serve in the position ... the end of 2018. Upon assuming the role of President and CEO on January ...
(Date:10/13/2017)... ... 13, 2017 , ... Apple Rehab Shelton Lakes , which specializes in ... the facility as part of a disaster drill on October 3rd. , Apple Rehab ... City Emergency Manager, as well as the Connecticut Long Term Care Mutual Aid ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House ... most popular and least understood books in the Holy Scriptures, Revelation. The Book of ... baffled scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... advisory services for healthcare compliance program management, will showcase a range of technology ... Association for Assisted Living (NCAL) Convention and Expo to be held October 14–18, ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics ... PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s ... of Morris F. Collen, a pioneer in the field of medical informatics, this prestigious ...
Breaking Medicine News(10 mins):
(Date:9/22/2017)... , Sept. 22, 2017 AVACEN Medical (AVACEN) ... is now successfully helping those with the widespread pain ... Fibromyalgia diagnosed Amanda in Essex, England ... washing my hair, experiencing no sleep at all, tremendous ... spasm… I cannot recommend [the AVACEN 100] enough, how ...
(Date:9/18/2017)... , Sept. 18, 2017 ... fields of bioinformatics and immune engineering, today ... protective avian influenza A (H7N9) vaccine. ... related to seasonal influenza and presents a ... on prior exposure to be effective. Using ...
(Date:9/12/2017)... , Sept. 12, 2017  ValGenesis Inc., ... Solutions (VLMS), is pleased to announce the appointment ... member of its Board of Directors and Chairman ... VLMS enables life science companies to manage their ... use of paper in this process. Furthermore, ValGenesis ...
Breaking Medicine Technology: