Navigation Links
Chloroquine and Primaquine combination Malarial drug for resistant parasites.

Researchers from LaTrobe University of Australia have found a new combination drug for combating Plasmodium falciparum, the parasite responsible for causing malaria. They used a combination of Chloroquine and Primaquine for treatment // helps in killing P. falciparum which is resistant to Chloroquine drug.

Chloroquine is a largely used drug in the treatment of malaria since 1950s. Chloroquine works by blocking the way the parasite breaks down human hemoglobin contained in red blood cells, the drug has to remain in a crystallized form to kill the parasite and an effective concentration of the drug has to accumulate in the digestive tract of the parasite in order to kill it. Due to indiscriminate abuse of Chloroquine the parasite has started to produce resistance to the drug, the parasit e can effectively neutralize the drug by developing a mechanism by which it drains the drug, so that the crystal form is not retained so the neutralized drug drains through the pores present in the digestive system with out forming considerable amount of the drug so which it does not have any effect on the parasite. So, the drug Chloroquine cures the symptoms but not the infection.

Researchers have tried to combine Chloroquine with Primaquine, a combination which would help to kill Chloroquine resistant parasites. Primaquine alone does not have any considerable effective activity on the parasite, but it acts by blocking the pores on the surface of the parasites digestive tract, so that this drug blocks the pores in the digestive tract, thereby does not allow the drug Chloroquine to drain.

Researcher Dr Leann Tilley said,
'"/>




Page: 1

Related medicine news :

1. The bad combination
2. Warding off symptoms of premenstrual syndrome by combination therapy
3. Cholesterol can be lowered using combination of Soy Proteins and Sterols
4. Nanocells cancer combination therapy acts as chemotherapy as well as anti-angiogenic drug
5. Calcitriol [Vitamin D] with combination of painkillers for cancer treatment
6. Eloxatin combination reduces bowel cancer recurrences
7. Death from heart attack can be reduced by new drug combination
8. New tetanus-diphtheria combination vaccine launched by Serum Institute of India
9. More effective Antiretroviral HIV drug combination
10. Salmeterol - to be used in combination & only when required
11. New chemo combination to fight breast cancer better
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network ... advocate for action towards gender equality at their inaugural Summit in New York City ... and reached a social audience of over 3 million. To watch the Mobilize Women ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to the ... save lost souls in the Philippines. “The Journey: From the Mountains to the Mission ... of the Bible. She has taught all ages and currently teaches a class of ...
(Date:10/12/2017)... Wis. (PRWEB) , ... October 12, 2017 , ... ... standard products to meet the demand of today’s consumer and regulatory authorities worldwide. ... of probiotic experts and tested to meet the highest standard. , These ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. ... recently contributed a medical article to the newly revamped Cosmetic Town journal ... spotlights the hair transplant procedure known as Follicular Unit Extraction (FUE). ...
(Date:10/12/2017)... ... October 12, 2017 , ... Health Literacy Innovations (HLI), ... software tool, and the Cancer Patient Education Network (CPEN), an independent professional organization ... a new strategic alliance. , As CPEN’s strategic partner, HLI will help ...
Breaking Medicine News(10 mins):
(Date:9/22/2017)... Sept. 22, 2017 AVACEN Medical (AVACEN) announced ... now successfully helping those with the widespread pain associated ... diagnosed Amanda in Essex, England ... my hair, experiencing no sleep at all, tremendous pain, ... I cannot recommend [the AVACEN 100] enough, how this ...
(Date:9/18/2017)... , Sept. 18, 2017 EpiVax, ... of bioinformatics and immune engineering, today announced ... influenza A (H7N9) vaccine. ... to seasonal influenza and presents a challenge ... prior exposure to be effective. Using state-of-the-art ...
(Date:9/12/2017)... SAN FRANCISCO , Sept. 12, 2017 /PRNewswire/ ... Lifecycle Management Solutions (VLMS), is pleased to announce ... as a member of its Board of Directors ... 2017. ValGenesis VLMS enables life science companies to ... eliminate the use of paper in this process. ...
Breaking Medicine Technology: