Navigation Links
Chloroquine and Primaquine combination Malarial drug for resistant parasites.

Researchers from LaTrobe University of Australia have found a new combination drug for combating Plasmodium falciparum, the parasite responsible for causing malaria. They used a combination of Chloroquine and Primaquine for treatment // helps in killing P. falciparum which is resistant to Chloroquine drug.

Chloroquine is a largely used drug in the treatment of malaria since 1950s. Chloroquine works by blocking the way the parasite breaks down human hemoglobin contained in red blood cells, the drug has to remain in a crystallized form to kill the parasite and an effective concentration of the drug has to accumulate in the digestive tract of the parasite in order to kill it. Due to indiscriminate abuse of Chloroquine the parasite has started to produce resistance to the drug, the parasit e can effectively neutralize the drug by developing a mechanism by which it drains the drug, so that the crystal form is not retained so the neutralized drug drains through the pores present in the digestive system with out forming considerable amount of the drug so which it does not have any effect on the parasite. So, the drug Chloroquine cures the symptoms but not the infection.

Researchers have tried to combine Chloroquine with Primaquine, a combination which would help to kill Chloroquine resistant parasites. Primaquine alone does not have any considerable effective activity on the parasite, but it acts by blocking the pores on the surface of the parasites digestive tract, so that this drug blocks the pores in the digestive tract, thereby does not allow the drug Chloroquine to drain.

Researcher Dr Leann Tilley said,
'"/>




Page: 1

Related medicine news :

1. The bad combination
2. Warding off symptoms of premenstrual syndrome by combination therapy
3. Cholesterol can be lowered using combination of Soy Proteins and Sterols
4. Nanocells cancer combination therapy acts as chemotherapy as well as anti-angiogenic drug
5. Calcitriol [Vitamin D] with combination of painkillers for cancer treatment
6. Eloxatin combination reduces bowel cancer recurrences
7. Death from heart attack can be reduced by new drug combination
8. New tetanus-diphtheria combination vaccine launched by Serum Institute of India
9. More effective Antiretroviral HIV drug combination
10. Salmeterol - to be used in combination & only when required
11. New chemo combination to fight breast cancer better
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... ... Journey: From the Mountains to the Mission Field”: the story of a missionary couple ... From the Mountains to the Mission Field” is the creation of published author, Carole ... and currently teaches a class of ladies at her church, which she has taught ...
(Date:10/12/2017)... Francisco, CA (PRWEB) , ... October 12, 2017 ... ... Dr. Cheng, are now treating sleep apnea using cutting-edge Oventus O2Vent ... apnea, a serious sleep disorder characterized by frequent cessation in breathing. Oral appliances ...
(Date:10/12/2017)... ... 12, 2017 , ... IsoComforter, Inc. ( https://isocomforter.com ), one of ... innovative new design of the shoulder pad. The shoulder pad provides optimal support ... your pain while using cold therapy. By utilizing ice and water that is circulated ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information about ... intend to develop to enable prevention of a major side effect of chemotherapy ... especially in pediatric patients. For cisplatin, hearing loss is FDA listed on-label as ...
(Date:10/12/2017)... ... ... Leading pediatric oncology experts at Children’s National Health System will ... the International Society of Paediatric Oncology (SIOP) Oct. 12-15. Chaired by Jeffrey ... Disorders at Children’s National, and Stephen P. Hunger, M.D., Chief of the Division ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... and NEW YORK , Sept. 27, 2017 /PRNewswire/ ... health and big data solutions, today announced that its MyDario product is ... your local TV listings for when The Dr. Oz Show airs in ... The nine-time ... month. ...
(Date:9/22/2017)... Sept. 22, 2017  As the latest Obamacare repeal ... Bill Cassidy (R-LA) and Lindsey Graham ... the medical device industry is in an odd place. ... the 2.3% excise tax on medical device sales passed ... want covered patients, increased visits and hospital customers with ...
(Date:9/18/2017)... ALLENTOWN , Pa. and KALAMAZOO, Mich. ... Allentown, Penn. , and OptiMed Specialty Pharmacy ... a business partnership to offer a strategic hub service ... PMD Healthcare,s highly sought-after personal spirometer, Spiro PD 2.0, ... A spirometer is a medical device used ...
Breaking Medicine Technology: