Navigation Links
Chloroquine and Primaquine combination Malarial drug for resistant parasites.

Researchers from LaTrobe University of Australia have found a new combination drug for combating Plasmodium falciparum, the parasite responsible for causing malaria. They used a combination of Chloroquine and Primaquine for treatment // helps in killing P. falciparum which is resistant to Chloroquine drug.

Chloroquine is a largely used drug in the treatment of malaria since 1950s. Chloroquine works by blocking the way the parasite breaks down human hemoglobin contained in red blood cells, the drug has to remain in a crystallized form to kill the parasite and an effective concentration of the drug has to accumulate in the digestive tract of the parasite in order to kill it. Due to indiscriminate abuse of Chloroquine the parasite has started to produce resistance to the drug, the parasit e can effectively neutralize the drug by developing a mechanism by which it drains the drug, so that the crystal form is not retained so the neutralized drug drains through the pores present in the digestive system with out forming considerable amount of the drug so which it does not have any effect on the parasite. So, the drug Chloroquine cures the symptoms but not the infection.

Researchers have tried to combine Chloroquine with Primaquine, a combination which would help to kill Chloroquine resistant parasites. Primaquine alone does not have any considerable effective activity on the parasite, but it acts by blocking the pores on the surface of the parasites digestive tract, so that this drug blocks the pores in the digestive tract, thereby does not allow the drug Chloroquine to drain.

Researcher Dr Leann Tilley said,
'"/>




Page: 1

Related medicine news :

1. The bad combination
2. Warding off symptoms of premenstrual syndrome by combination therapy
3. Cholesterol can be lowered using combination of Soy Proteins and Sterols
4. Nanocells cancer combination therapy acts as chemotherapy as well as anti-angiogenic drug
5. Calcitriol [Vitamin D] with combination of painkillers for cancer treatment
6. Eloxatin combination reduces bowel cancer recurrences
7. Death from heart attack can be reduced by new drug combination
8. New tetanus-diphtheria combination vaccine launched by Serum Institute of India
9. More effective Antiretroviral HIV drug combination
10. Salmeterol - to be used in combination & only when required
11. New chemo combination to fight breast cancer better
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/28/2016)... ... ... a part of the city where’s it’s easy to spot the neon lights of chains ... to attract diners with a taste for real food. , On May 13, the ... Grill, an urban casual restaurant focusing on dishes made by hand with wholesome, organic ingredients ...
(Date:5/27/2016)... New Hampshire (PRWEB) , ... May 27, 2016 , ... ... skin care products, announced today that it has been recognized as one of the ... entering parenthood. Badger was named as one of nine small businesses providing progressive benefits ...
(Date:5/27/2016)... ... May 27, 2016 , ... An educational ... by inspiring human-interest stories, courtesy of awareness-driven celebrities and thought leaders. It also ... advocates, associations and industry leaders such as Bioness. , As patients feel ...
(Date:5/27/2016)... ... ... Aimed at nurses and employees in the health care world, this installment ... nursing and health care industry. It also provides insight to the developing trends and ... As the nursing industry is coming out of one of the biggest recessions in ...
(Date:5/26/2016)... ... May 26, 2016 , ... There are many ways ... and Sausage Council (NHDSC) suggests that Americans prefer their dogs straight off the grill. ... say grilling is their favorite way to cook a hot dog, far outpacing other ...
Breaking Medicine News(10 mins):
(Date:5/30/2016)... May 30, 2016 According ... Testing Services Market by Type (Stability, Raw Materials, ... End User (Pharmaceutical Companies, Medical Device Companies) - ... market witnessed healthy growth during the last decade ... of 11.3% between 2016 and 2021 to reach ...
(Date:5/30/2016)... On 28 May, 194 Member States ... At the 69 th World Health Assembly, governments unanimously ... signalling the greatest global commitment in viral hepatitis to date. ... B and C by 2030 and includes a set of ... deaths by 65% and increase treatment to 80%, saving 7.1 ...
(Date:5/30/2016)... PUNE, India , May 30, 2016 /PRNewswire/ ... Pipeline Review, H1 2016" market research report with ... Colitis, complete with comparative analysis at various stages, ... (MoA), route of administration (RoA) and molecule type, ... press releases. It also reviews key players involved ...
Breaking Medicine Technology: