Navigation Links
Chinese Medicinal Compound Stops Formation of Cysts in Polycystic Kidney

Using a compound from a centuries-old Chinese traditional medicine, Yale University researcher Dr. Craig Crews has been able to prevent the formation of kidney-destroying// cysts in a mouse model of polycystic kidney disease. This ability holds out hope for what would be the first treatment, other than kidney transplant or frequent dialysis, for one of the most lethal of all kidney diseases worldwide.

Triptolide is derived from a Chinese medicinal herb, named Lei Gong Teng, which has been used in traditional medicine to treat cancer, inflammation, and auto-immune diseases and, more recently, also has been tested in Phase I clinical trials as an anti-tumor agent.

This study, with mice bred to have a disease like human polycystic kidney disease, used triptolide with a less toxic concentration than that used in cancer chemotherapy trials. At that level, the compound marked reduced cyst formation in the mice compared to genetically similar mice not taking the compound.

During normal kidney development, cells lining the kidney tubules continue growing and dividing until they receive a signal that the tubule is fully formed. The switch that turns on that signal consists of the growth regulatory proteins PKD1 and PKD2, located on hair-like cilia in the lining of the developing tubules. When urine begins flowing through the tubules, the flow bends the cilia that sets off the signal that no more growth is needed.

In people who have a mutation in one of these growth regulatory proteins, however, the message to stop growing never gets delivered, even when urine is flowing and the cilia are bending. It is as if the phone is ringing but the cell can't hear it. So, never sensing a signal to stop, the cells lining the fully-formed kidney tubules keep right on subdividing and growing. The result of this hyperproliferative, unregulated growth: uncontrolled growth of cells lining the tubules and the formation of large cysts in the kidn
'"/>




Page: 1 2

Related medicine news :

1. Chinese paracetamol may be slapped with dumping duty
2. Stay young the Chinese way
3. A Chinese herb kills cancer cells
4. Chinese herbal remedies aids in cancer treatment
5. Prohibited diet medicine found in Chinese herbs
6. Global Outbreak Of Bird Flu Warning By Chinese Scientist
7. Japanese And Chinese Pharmaceutical Companies Join Together In Drug Testing
8. Unscrupulous Chinese Medicine traders putting lives at risk
9. Chinese City Suspends Water Supply Fearing Pollution
10. Running Water Restored In Chinese City
11. Mass Bird flu vaccination to Chinese Poultry
Post Your Comments:
(Date:5/25/2015)... ProDrop Light Show allows users to now ... with a click of a mouse. Users have full control over ... Final Cut Pro X. , ProDrop Light Show gives users 30 ... and much more leaving infinite possibilities all within Final Cut Pro ... text presets, users can apply their very own media files or ...
(Date:5/25/2015)... (PRWEB) May 25, 2015 After the ... the radical science-based human wellness company Trivedi Master ... event from their world-class series titled, “Consciousness is Power.” ... on June 13, 2015 at the routinely allotted time ... The event will be made available to the public ...
(Date:5/25/2015)... White Plains, NY (PRWEB) May 25, 2015 ... LEED AP, principal of PBDW Architects in New York City, ... which is part of the hospital’s ongoing Legacy Lobby Lecture ... campus in White Plains. White is the great grandson of ... firm responsible for the design of Burke’s campus 100 years ...
(Date:5/24/2015)... 25, 2015 Pacific Prime has announced that they ... looking at the cost of individual international health insurance. Titled: ... looks at the cost of health insurance in six top expat ... Hong Kong , Singapore , ... UAE , the UK , Article 2 ...
(Date:5/24/2015)... Michigan (PRWEB) May 24, 2015 ... concerns about hair loss. Although it is unclear about ... there are environmental factors such as metabolism, nutritional deficiencies, ... Since they offer a comprehensive approach to evaluating the ... post-menopausal woman, they can help patients find a cause ...
Breaking Medicine News(10 mins):Health News:Developers at Pixel Film Studios Release of ProDrop Light Show for Final Cut Pro X. 2Health News:Hundreds of People Are Thrilled to Hear that Trivedi Master Wellness™ Promises to Hold Another Workshop in June 2015 2Health News:Hundreds of People Are Thrilled to Hear that Trivedi Master Wellness™ Promises to Hold Another Workshop in June 2015 3Health News:Burke Rehabilitation Hospital Welcomes Architect Samuel White, Descendant of McKim, Mead and White, for Legacy Lobby Lecture 2Health News:Burke Rehabilitation Hospital Welcomes Architect Samuel White, Descendant of McKim, Mead and White, for Legacy Lobby Lecture 3Health News:Pacific Prime Releases 2nd Article of Cost of Health Insurance Report 2Health News:Women's Excellence Now Treats Menopausal Hair Loss 2
... 23 Jazz,Pharmaceuticals, Inc. (Nasdaq: JAZZ ) ... will provide a corporate presentation at the,Morgan Stanley ... May 1, 2008 at 8:00 a.m. Eastern Time., ... be accessed by visiting the,Investors section of the ...
... develops simple test to identify those at risk ... self-administered test to identify surgical patients who may have ... by a team of Canadian anesthesiologists. , People ... they sleep. The disorder affects 2 percent to 26 ...
... to Meet Today,s Healthcare Challenges, WELLINGTON, ... (AMEX: QGP, QGP.WSA, QGP.WSB) (http://www.QuantumMD.com ) ... J. Guillama has been asked to deliver ... Annual Life,Science Conference, "Leveraging Information Technology to ...
... HUNTINGTON, N.Y., April 23 MediCepts, Inc. is ... P.C. as,the first practice in New York State ... System(TM) to its neck and back pain,patients. Owned ... and Tony Corso, MS,PT, Corso Rehabilitation and Physical ...
... Ice Cream and, Limited-edition CD at Participating Stop & Shop Stores on ... ... 23 Everyone,s a,winner when you stop into participating Stop & Shop ... Winner Game,Scoop(R) Day event., This year, EDY,S Grand Ice Cream hopes ...
... Dining Room for the Poor, SAN FRANCISCO, April 23 ... choice but to carefully utilize every resource it,has. Using a ... St. Anthony,s offers 2,600 sustainably managed,healthy and filling meals 365 ... per serving; and at no cost to the hungry Dining ...
Cached Medicine News:Health News:Sleep Apnea Screening Cuts Surgical Complications 2Health News:The Quantum Group CEO to Deliver Keynote Address at EDC Life Science Conference 2Health News:The Quantum Group CEO to Deliver Keynote Address at EDC Life Science Conference 3Health News:The Future of Spine Care Has Just Gotten Better With the Use of SpineSix BioMotion Spinal System(TM) 2Health News:EDY'S(R) Slow Churned(R) and Stop & Shop Stores Announce Scoop Day With Sweet Deals to Support the Fight Against Childhood Cancer 2Health News:The Greening of St. Anthony's 2
(Date:5/22/2015)... May 22, 2015  BioLife Solutions, Inc. (NASDAQ: BLFS ... grade hypothermic storage and cryopreservation freeze ... and tissues ("BioLife" or the "Company"), announced that the Company ... The Company is scheduled to present at ... 2015 at the Grand Hyatt Hotel in New ...
(Date:5/22/2015)... Fla. , May 22, 2015 ... Heart Institute recently traveled to Boston, ... procedure at the 2015 Heart Rhythm Society conference. ... together to focus on the ideas, people and ... Convergent is a hybrid, minimally invasive cardiac ...
(Date:5/22/2015)... The North American dental lasers market ... to reach $90.7 million by 2019, at a CAGR of ... TOC of North America Dental Lasers Market for an analysis ... tables and figures. http://www.micromarketmonitor.com/market/north-america-dental-lasers-1771208223.html ...   Dental lasers are specifically used in ...
Breaking Medicine Technology:BioLife Solutions To Present At The 2015 Marcum MicroCap Conference In New York City 2St. Joseph's Hospital Heart Institute Physician Presents at Heart Rhythm Society 2St. Joseph's Hospital Heart Institute Physician Presents at Heart Rhythm Society 3North America Dental Lasers Market is Expected to Reach $90.7 Million by 2019, at a CAGR of 9.2% From 2014 to 2019 2North America Dental Lasers Market is Expected to Reach $90.7 Million by 2019, at a CAGR of 9.2% From 2014 to 2019 3
... Corporation (NYSE: CFN ) today announced plans to release third quarter results ... trading on the New York Stock Exchange. , ... company will host a webcast and conference call on May 6 at ... the results for its third quarter, ended on March 31, 2010 . To ...
... Therapeutics To Present at Deutsche Bank,s 35th Annual Healthcare ... over PR Newswire, we are advised by the company ... the presentation time has been updated to 8:00 ... as originally issued. The complete, updated release follows: , ...
Cached Medicine Technology:CareFusion Will Host an Earnings Conference Call on May 6 to Discuss the Results for the Third Quarter of Fiscal 2010 2Cornerstone Therapeutics To Present at Deutsche Bank's 35th Annual Healthcare Conference 2Cornerstone Therapeutics To Present at Deutsche Bank's 35th Annual Healthcare Conference 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: