Navigation Links
Chilli Extract may Stop Fat Cell Growth

Capsaicin, the compound that gives red pepper its heat, could inhibit the growth of fat cells, says a new laboratory study.//

If the results can be replicated in further studies, the results could see a strengthening of capsaicin in the weight management supplements market, currently estimated by Euromonitor International to be worth US$0.93bn (€0.73) in Europe in 2005 and $3.93bn in the US.

"The results of this study clearly showed that capsaicin could inhibit the population growth and the induction of apoptosis [programmed cell death] in 3T3-L1 preadipocytes [cells that can be stimulated to form fat cells]," wrote Gow-Chin Yen and Chin-Lin Hsu in the Journal of Agricultural and Food Chemistry.

The researchers, from the National Chung Hsing University in Taiwan, note that previous studies have suggested that obesity may be reduced by preventing immature fat cells (adipocytes) from developing into mature cells, and other studies have shown that capsaicin can decrease the amount of fat tissue and decrease fat levels in the blood.

Over 300m adults are obese worldwide, according to latest statistics from the WHO and the International Obesity Task Force. About one-quarter of the US adult population is said to be obese, with rates in Western Europe on the rise although not yet at similar levels.

Yen and Hsu used pre-adipocyte cells called 3T3-L1from mice and exposed them to doses between 0 and 250 micromoles solutions of capsaicin and incubated them for 24, 48 and 72 hours, and found that capsaicin inhibited cell population growth in a dose and time dependent manner.

The effects of this inhibition would be at levels just slightly greater than those found in the stomach fluid of an individual eating a typical Indian or Thai diet, the researchers said.

"The intake of capsaicin in a typical Indian or Thai diet was about 128 micrograms per kilogram human body weight. The concentrations of ca psaicin in the gastric fluid would be equivalent to 8-25 micromoles for an adult human with a body weight of 60 kg," wrote Yen and Hsu.

A mechanistic study revealed that capsaicin adversely affected protein expression by the apidocytes, most notably PPAR?, which is reported to regulate several genes involved in the formation of fat cells, as well as making body fat.

"Capsaicin… inhibited lipid accumulation and the protein expression of PPAR?… These results demonstrate that capsaicin efficiently suppresses adipogenesis in 3T3-L1 pre-adipocytes and adipocytes," concluded the researchers.

Capsaicin has been used in folk medicine as a remedy for rheumatism. The humble red chilli pepper has also been in the news recently with research linking the spice to inhibiting the growth of pancreatic cancer cells, as well as a growing body of studies suggesting it may cut fat and energy intake when added to the diet.

Some caution should also be exercised as high intake of hot chillies has been linked with increased risk of stomach cancers in the populations of India and Mexico.

Source-Bio-Bio Technology
SR
'"/>




Related medicine news :

1. Eat Chillies, Burn Fat
2. Extracts of grapefruit heals stomach ulcers
3. Yet Another Use For Green Tea Extract
4. Tomato Extract Found To Reduce The Risk Of Thrombosis
5. Slowing Cartilage Loss In Arthritis With Fruit Extracts
6. High Blood Pressure Can Be Treated With Grape Seed Extract
7. Saw Palmetto Extract No Good In Improving Prostate Health
8. A Mushroom Extract May Impact the Body’s Immune Syste
9. Hot Flashes Could Be Minimized By Rhubarb Extract
10. Skin Damages Caused by Cancer Radiation Therapy Reduced by Tea Extracts
11. Mushroom Extract Protects Poultry From Parasite Diseases
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/20/2017)... ... September 20, 2017 , ... Each year Athletic Trainers from ... Trainers’ Association Annual Clinical Symposium and Expo. New research is revealed, evidence based ... Trainers are acknowledged by their peers with accolades and highly prestigious awards. This ...
(Date:9/20/2017)... ... 2017 , ... Medicare doesn’t have the authority to negotiate ... their prescription drugs, according to a new comparison of drug plans by ... there’s no consistency in drug pricing among drug plans,” states TSCL’s Medicare policy ...
(Date:9/20/2017)... ... 20, 2017 , ... “Finn Mouseson”: follows the exciting story of a mouse ... mouse sets out on a journey that will show that friends are to be ... newly published author and illustrator, Melody Gersonde-Mickelson, who has earned a bachelor’s degree in ...
(Date:9/20/2017)... ... ... “The Financial Favor of God; Second Edition”: a personal and exquisite recipe for ... of published author, Brooks Rathell. , “We typically hear about the favor of God. ... favor of God. Not only does it exist, but it is meant for you. ...
(Date:9/19/2017)... ... September 19, 2017 , ... DeSola Group, a ... leader, Denise Flannery, to its strategic advisory and client development team. , ... work with clients across different industries to develop and implement market-justified strategies, modernize ...
Breaking Medicine News(10 mins):
(Date:9/1/2017)... N.J. , Sept. 1, 2017  Bayer will present ... the European Society for Medical Oncology (ESMO) 2017 Congress, September ... presented will include new preclinical and clinical data on Bayer,s ... two earlier pipeline projects. ... the best minds in cancer research at ESMO," said ...
(Date:8/29/2017)... -- ivWatch, LLC, the leading provider of continuous monitoring devices for ... awarded an Innovative Technology contract from Vizient, Inc., the largest member-driven ... ... early detection of peripheral IV infiltration and extravasation events ... The Innovative Technology contract was awarded to ivWatch based ...
(Date:8/28/2017)... -- Hill-Rom Holdings, Inc. (NYSE: HRC), will present at the ... in New York . John Greisch ... present at 11:05 a.m. Eastern Time. The ... A recorded replay will be available one hour after the ... About Hill-Rom Holdings, Inc. ...
Breaking Medicine Technology: