Navigation Links
Childhood Cancer Survivors May Suffer Health Problems in Adulthood

Children with cancer have almost a 80% chance of winning a battle with cancer, as opposed to adults, and children who were diagnosed for cancer 20 to 30 years ago.// A recent report has explained that despite braving odds and coming out of cancer, this does not absolve them from the risks of long-term health problems in adulthood.

One of the co-authors of the Childhood Cancer Survivor Study is a long-standing pioneer in the field. Anna T. Meadows, M.D., and colleagues at The Children's Hospital of Philadelphia were the first researchers to investigate the late effects of childhood cancer, starting in the mid-1970s. An oncologist, Dr. Meadows is the medical director of the Cancer Survivorship Program at Children's Hospital. Dr. Meadows serves on the steering committee of the Childhood Cancer Survivor Study (CCSS), which published the research, the largest-ever study of adult survivors of childhood cancer in the Oct. 12 issue of the New England Journal of Medicine. Sponsored by the National Cancer Institute, the collaborative study drew on researchers from more than two dozen cancer centers throughout the U.S. and Canada.

In comparing more than 10,000 adult survivors of pediatric cancer to approximately 3,000 of their siblings, the researchers found survivors to be more than three times as likely to have chronic health condition, and more than eight times as likely to have a severe or life-threatening condition. The incidence of these chronic conditions increased over time and did not appear to level off over the time span that was studied.

The long-term survivors, first diagnosed with cancer between 1970 and 1986, were particularly vulnerable to second cancers, heart conditions, kidney disease, severe musculoskeletal problems and endocrine abnormalities such as thyroid disease, osteoporosis and sterility. Female survivors were at higher risk than male survivors for chronic illnesses.

One implication of the current study, said Dr. Meadows, is the need for continued medical surveillance of adult survivors of childhood cancer. "Fewer than 20 percent of these patients are followed by an oncologist or at a cancer center, but they clearly have special medical needs and higher risks," she added. There are currently 270,000 survivors of pediatric cancer in the U.S.

Dr. Meadows is nationally recognized as an expert in treatment-related effects of children's cancer. Her studies in the 1970s and 1980s showed that brain radiation used to treat children with leukemia damaged the children's cognitive development and raised their risk of later brain cancer. That research helped to change medical practice, as physicians eliminated or reduced radiation doses to the head during treatment for childhood leukemia.

Because of such studies on treatment effects, and based on many clinical trials in pediatric oncology that have led to improved treatments over the years, Dr. Meadows predicts that children diagnosed with cancer since 1987 will have fewer chronic problems as survivors than the cohort analyzed in the current study.

On the strength of her clinical and research experience with childhood cancer survivors, Dr. Meadows became the first director of the Office of Cancer Survivorship at the National Cancer Institute, serving from 1996 to 1999. She has been part of the CCSS since its inception in 1993, and chairs its publication committee, guiding the organization's output of some 50 articles.



Source-Eurekalert
'"/>




Related medicine news :

1. Focused Treatment For Childhood Cancer
2. Osteoporosis associated with Childhood Cancer
3. Childhood Sunburn Can Lead to Skin Cancer Later
4. Preventing Childhood Deaths
5. Radiation Not Needed for Childhood Cancers
6. Troubled Childhood found to affect your Liver
7. Elevated LDL levels in Childhood could be Predictors of Heart Disease
8. Persistent Childhood Wheeze Probably Inherited
9. Childhood Weight Gain Found To Increase The Risk of Diabetes
10. The Link Between Childhood Vaccinations And Diabetes Questioned
11. Troubled Childhood found to affect your Liver
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/6/2016)... Sacramento, CA (PRWEB) , ... December 06, 2016 , ... ... travel can disrupt daily routines. That means it's also the season when eating healthy, ... those living with diabetes) on schedule is harder to do. , "Shopping trips, ...
(Date:12/6/2016)... ... December 06, 2016 , ... “Tatiana Sibirskaya: ... powerful woman's story of sacrifice and enlightenment. , “Tatiana Sibirskaya: A ... Fryer. Always looking for creative outlets, Carolyn gravitated toward writing through the inspiration ...
(Date:12/6/2016)... ... 06, 2016 , ... TopConsumerReviews.com recently gave a best-in-class 5 star rating to ... give freedom to people who need help getting around. For some, advancing age has ... period of rehabilitation after an illness or accident. There is a wide variety of ...
(Date:12/6/2016)... California (PRWEB) , ... December 06, 2016 , ... "Add ... users to flicker, flash, and flare from clip to clip with high quality 4K ... , TransFlare 4K Jewel contains 44 lens flares filmed on the RED Dragon. Utilizing ...
(Date:12/5/2016)... ... , ... What: Shriners Hospitals for Children, with the help of Dimension Data, ... a video monitor and web-enabled camera. Santa visits with children through Dimension Data’s program ... Wonderland, which is where the video connection to the North Pole will stream. Much ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... , Dec. 5, 2016  Balloon catheter is ... which is inserted into the femoral artery in the ... arm to treat constricted blood vessels. These products are ... to atherosclerosis – deposition of lipid substances in the ... catheter market is projected to expand at a CAGR ...
(Date:12/5/2016)... , Dec. 5, 2016 Spain Glaucoma Surgery ... new report, "Spain Glaucoma Surgery Devices Market Outlook to ... Surgery Devices market. The report provides value, in millions ... (USD) within market segements - Canaloplasty Micro Catheters and ... shares and distribution shares data for each of these ...
(Date:12/5/2016)... 5, 2016  Cornerstone Pharmaceuticals, Inc., a privately ... from two Phase I trials evaluating its lead ... annual meeting of the American Society of Hematology ... . The two datasets show encouraging efficacy and ... (AML) and T-cell non-Hodgkin,s lymphoma (T-cell NHL), respectively, ...
Breaking Medicine Technology: