Navigation Links
Chemotherapy Drug Shrinks Brain Tumors

Cancerous brain tumors appear to respond favorably to the drug temozolomide when used as primary chemotherapy after surgery, and the treatment appears to work best in people missing a certain gene. The study was published in the scientific journal of the American Academy of Neurology.

Researchers studied 149 people with low grade gliomas, a slow-growing type of brain tumor, who were treated with temozolomide chemotherapy for up to 30 months.

The study found temozolomide reduced the size of brain tumors in 53 percent of the study's participants and stabilized the size of brain tumors in 37 percent of the study's participants. However, in 10 percent of the group, the size of the brain tumors increased by more than 25 percent.

Genetic testing was also performed in 86 of the participants. In 42 percent of the participants, the gene 1p/19q was missing. Those missing the gene were more likely to respond well to the drug. They also had more months without the tumor developing than those with the gene and were less likely to die during the study.

"Our findings are consistent with previous smaller studies showing temozolomide as a primary treatment is effective and tolerable, and an added benefit is the discovery that the loss of chromosome 1p/19q predicts how well a person is going to respond to the treatment," said study author Khe Hoang-Xuan, MD, PhD, with the Pitie-Salpetriere Hospital in Paris, France.

However, Hoang-Xuan says comparing temozolomide to radiotherapy, which is the standard treatment for such brain tumors, isn't easy and he says that's why continued research into comparing the two treatments is needed.


Page: 1

Related medicine news :

1. Acupuncture May Help Chemotherapy Side Effects
2. Chemotherapy Pill Has Fewer Side Effects Than IV
3. Survival rates in breast cancer patients improved with "Dose Dense Chemotherapy"
4. Therapy Boosts Chemotherapy Effects
5. Chemotherapy Effective for Bladder Cancer
6. New Method Of Delivering Chemotherapy
7. The Benefits Of Chemotherapy For Women With Ovarian Cancer
8. New Compound Could Strengthen The Effect Of Chemotherapy
9. Older Breast Cancer Patients Can Be Effectively Treated With Chemotherapy
10. Treating Testicular Cancer With A Single Dose Of Chemotherapy
11. Ginger Found To Reduce Nausea Associated With Chemotherapy
Post Your Comments:

(Date:12/1/2015)... ... December 01, 2015 , ... McLean, VA., December ... a fixed price per sprint agile development contract to support the National Geospatial-Intelligence ... five years, provides software engineering, infrastructure, as well as operations and sustainment support ...
(Date:12/1/2015)... ... December 01, 2015 , ... TCS ... care management and population health arenas, is pleased to announce that VIP Care ... services, has successfully implemented the ACUITY Complete Care™ Management to back their collaborative ...
(Date:12/1/2015)... CA (PRWEB) , ... December 01, 2015 , ... ... has selected 10 semi-finalists to head to Las Vegas for CES 2016, the world’s ... including CEO of Consumer Technology Association Gary Shapiro, Founding Partner of Pacific Investments Veronica ...
(Date:12/1/2015)... Aliso Viejo, CA (PRWEB) , ... December 01, 2015 , ... ... any length of footage, and with full control over customization, the possibilities are truly ... color, frame rate, position randomization, overlay depth position, vertical flip, horizontal flip, depth of ...
(Date:12/1/2015)... ... December 01, 2015 , ... ... Magazine as a Modern Man for 2015. , Angeleno Magazine is a ... United States. Established in 1994, Modern Luxury includes more than 50 magazine titles ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... 1, 2015 Breg, Inc ., a ... today that it has been awarded three contracts by ... by Novation will have access to improved pricing for ... and soft goods dedicated to advancing orthopedic care.  ... aging U.S. population, rising prevalence of chronic conditions and ...
(Date:12/1/2015)... N.J. , Dec. 1, 2015 ... against HIV/AIDS, Johnson & Johnson (NYSE: JNJ ... its Janssen Pharmaceutical Companies to significantly reduce the ... who make up 74 percent of new HIV ... Announced on World AIDS Day, these new initiatives ...
(Date:12/1/2015)... 1, 2015 Relmada Therapeutics, Inc. (OTCQB: RLMD), a ... pain, announced today that the company will present at the ... 1-3 at the Luxe Sunset Boulevard Hotel in ... of Relmada Therapeutics, will present on Thursday, December 3, at ... . Please register at least 10 minutes prior to ...
Breaking Medicine Technology: