Navigation Links
Change in Course of Treatment: Exploring Better Ways

At the Annual Meeting of the American Society of Clinical Oncology today, the results of a large, multicenter, international study laying the groundwork for decisions that included when or if a change in treatment should be made were presented.

In patients with metastatic colorectal cancer, counting circulating tumor cells before and after the start of treatment could help doctors decide when and if a change in course of treatment is necessary.

Few studies have examined the relationship of CTC and a patient's prognosis in cancer. This is an important area of research in metastatic colorectal cancer because there are little data to help physicians chose which treatment is best for which patients or to determine when a change in treatment is warranted.

"If we had a way to know early on that a tumor isn't responding to a particular drug, we could switch to a different treatment before growth of the cancer is seen on a CAT scan," said Neal J. Meropol, director of the gastrointestinal cancer program at Fox Chase Cancer Center and lead investigator of the study. "If we could determine that the tumor was destined to grow after a few weeks of treatment, we'd be able alter course even before the first scan."

For this study, Meropol and his colleagues examined the association between the circulating tumor cell number and progression-free and overall survival for 430 adult patients with metastatic colorectal cancer.

The number of CTC was measured at baseline, one month, and several other points after the start of treatment. CTC were isolated and counted by an immunomagnetic cell separation technique, an FDA-approved technology developed by Immunicon Corporation. CT scans were obtained in usual practiceat baseline and every 6-12 weeks after starting treatment. Having 3 or more CTC (per 7.5 mL of blood) was defined as "unfavorable" in an initial analysis. Patients with fewer than 3 CTC were considered favorab
'"/>




Page: 1 2

Related medicine news :

1. GlaxoSmithKline - Changes Lamictal(R) Label Appearance and Packaging
2. Change in walking might indicate Dementia
3. Change in weight not a risk in healthy men
4. Changes in cabin pressure pose risks for moms-to-be
5. Dietary Changes Could Reduce The Risk for Stroke
6. Link Between High Blood Sugar And Behavioral Changes
7. Improving Lighting Could Bring About A Change In Alzheimers Patients
8. Specific Changes In A Particular Gene Found To Increase The Risk of Alzheimer’s Diseas
9. Impotence Drugs Ordered by FDA to have Label Change
10. Ultrasounds To Detect Changes In Heart Motions
11. Change In Diet May Slow The Progression Of Prostate Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Change Course Treatment Exploring Better Ways

(Date:9/23/2014)... of Cambridge has found that a common characteristic of autism ... in the brain. The results are published today (23 September) ... researchers studied 80 adult men with autism: 38 who had ... that language delay was associated with differences in brain volume ... insula, ventral basal ganglia, which were all smaller in those ...
(Date:9/23/2014)... France (PRWEB) September 23, 2014 Névo ... designing a precision timepiece and adding advanced activity tracking ... that continuously monitors steps, distance, calories burned, and more. ... the need to adopt healthy habits in their busy ... to quantify small changes that produce healthy results, but ...
(Date:9/23/2014)... (PRWEB) September 23, 2014 Medicine in Motion ... central Austin location at 711 W. 38th, Suite G4. After ... their north Austin location, increased demand for MIM’s superior care ... team and I are extremely excited about bringing our high-quality ... Pyron, owner of Medicine in Motion. “We’ll continue to provide ...
(Date:9/22/2014)... September 23, 2014 The Gesundheit! Institute ... a new design and restructuring for their existing website. The ... grown. They needed a way to navigate to the different ... well as present the look and feel of the site ... In 1971, when Patch Adams graduated from The Medical School ...
(Date:9/22/2014)... September 23, 2014 Career Step, ... training, will be attending and exhibiting at the ... Health Information Management Association (AHIMA) in San Diego, ... through October 1, and Career Step will be ... suite of coding training products, including CLiM™, its ...
Breaking Medicine News(10 mins):Health News:Presence or absence of early language delay alters anatomy of the brain in autism 2Health News:Nevo changes the face of fitness wearables with an analogue watch combining activity tracking, phone notifications, and LED goal progress indicators for active lifestyles 2Health News:Nevo changes the face of fitness wearables with an analogue watch combining activity tracking, phone notifications, and LED goal progress indicators for active lifestyles 3Health News:Austin Sports Medicine Practice to Host Grand Opening Event for Second Location 2Health News:Idea Marketing Group Launches a New Website for The Gesundheit! Institute 2Health News:Idea Marketing Group Launches a New Website for The Gesundheit! Institute 3Health News:Career Step to Exhibit at AHIMA Convention September 27 through October 1 2
... consider home to be the safest place for deliveries, are ... ,The Gandhi Manav Kalyan Society, an ... the study of the reproductive health of over 315 women ... level of health care among women in the region. According ...
... and other northern mid- and upper-latitude regions are playing ... thought , according to a study appearing in this ... light on the so-called missing carbon sink, concludes that ... of carbon dioxide from the atmosphere, thereby partially offsetting ...
... dont believe that a good sense of humour or great look ... partners kissing skills . ,A poll by online dating agency ... because they were a miserable kisser. ,Eight out of ... said that being a bad kisser was likely to mean the ...
... her growing years that doctors thought she had brain tumour . ... eight till she was 13, when her parents separated. ... stress of her parents troubled married life. ,The 19-year-old ... was all in her head, and though the memories werent great, ...
... the University of California, San Diego (UCSD) Skaggs School ... for developing a human vaccine to prevent against ... a type of herpes virus, is the leading viral ... patients with compromised immune systems. The bodys natural immunity ...
... An Indian Yoga expert has organized a three-day workshop on ... Mishra, the founder director of Yoga Darshan, India, in his ... Chan Wellness Club, said, yoga could help the people of ... ,Yoga can help Lahoris keep healthy, said Dr ...
Cached Medicine News:Health News:Poor Health Practices Plague Rajasthan Tribal Women 2Health News:Northern Forests Less Effective Than Tropical Forests in Reducing Global Warming 2Health News:Northern Forests Less Effective Than Tropical Forests in Reducing Global Warming 3Health News:Human Vaccine for Herpes Virus on the Anvil 2Health News:Human Vaccine for Herpes Virus on the Anvil 3
(Date:9/22/2014)... MEDICAL CORP. (NYSE: CMN ) will release  the ... 31, 2014 on Monday, September 29 before the market opens, ... 11:00 AM ET. Participating in the call will be ... President and CEO; Jorgen B. Hansen , Executive Vice ... President, CFO and Treasurer; and Seth Yellin , Senior ...
(Date:9/22/2014)... Sept. 22, 2014  For many people experiencing ... means facing the prospect of large, painful incisions ... regular activities are also impacted, such as working, ... of the problem, some patients even delay necessary ... even lead to permanent damage for some conditions. ...
(Date:9/22/2014)... 22, 2014  Inovio Pharmaceuticals, Inc. (NASDAQ: ... a phase I clinical trial in patients with ... tolerability, and immunogenicity of INO-3106. This immunotherapy targets ... aerodigestive cancers. Aerodigestive cancers affect the ... parts of the esophagus and windpipe. The unmet ...
Breaking Medicine Technology:Cantel Medical Corp. To Hold Conference Call To Discuss Results For Its Fourth Quarter And Fiscal 2014 Ended July 31, 2014 2Phoenix Arizona Hand Doctor Develops Revolutionary New Surgery System, Eliminates Need for Large Incisions 2Inovio Pharmaceuticals Expands HPV Immunotherapy Development to Aerodigestive Cancers 2Inovio Pharmaceuticals Expands HPV Immunotherapy Development to Aerodigestive Cancers 3Inovio Pharmaceuticals Expands HPV Immunotherapy Development to Aerodigestive Cancers 4
... (Nasdaq: REGN ) (the "Company"), today announced that ... of its common stock pursuant to an underwriting agreement with ... Company expects to use the net proceeds from the sale ... offering is expected to occur on or about October 11, ...
... at Self Regional Healthcare,s South Carolina Spine Center in ... of spinal conditions in its new advanced surgical operating ... Already recognized by leading health care ratings organization HealthGrades ... its commitment to advanced spinal care by becoming the ...
Cached Medicine Technology:Regeneron Pharmaceuticals, Inc. Announces The Sale of 4,500,000 Shares of Common Stock 2Regeneron Pharmaceuticals, Inc. Announces The Sale of 4,500,000 Shares of Common Stock 3Self Regional Healthcare Becomes First in the Southeast to Treat Spine Patients Using Advanced Integrated Operating Room Technology From Brainlab 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: