Navigation Links
Cervical Cancer Can Now Be Better Handled With Gene Silencing Therapy

Queensland University researchers have ventured into a new approach called ‘gene silencing’ for the treatment of cervical cancer. The technique is targeted towards turning // the cancer causing genes on and off to help cervical cancer patients.

Certain genes called tumor suppressor genes are responsible for preventing the occurrence of a particular type of cancer. On the other hand, tumor-promoting genes help in the initiation and progression of tumor. A logical way to combat tumor is to either turn on the tumor suppressor genes or turn off the tumor promoting genes.

Cervical cancer is the leading cause of cancer death in women aged 25-50 worldwide. Infection with the human papilloma virus is regarded to be a causative factor in cervical cancer as it results in the over-production of two viral cancer-causing genes called E6 and E7.

The researchers were successful in killing the cervical cancer cells by turning of the production of these genes in cancer cells. Furthermore, gene silencing was found to enhance the effect of chemotherapy by up to four times.

One main advantage of this approach is that the normal cells remain unaffected during manipulation, as the main target is the viral gene. The researchers hope to exploit this form of treatment to all forms of cervical cancer including the premalignant lesions picked up by the pap smear and especially for advanced cervical cancers where the cancer has moved to other sites such as the lung or liver.

The current results have been demonstrated in cervical cancer cell lines grown in test tubes. The next step is to achieve the same desired effect in animal models. If successful, the next stage of research will focus on the development of materials for human trials to allow proper delivery of the drug to patients and to investigate whether other cancer types can be treated this way.

Although the trials are under an experimental phase, if successful, it can turn out to be an advanced form of the currently existing treatment options such as surgery, radiotherapy and chemotherapy. At the least, a cancer-specific treatment for advanced cervical cancers would be arrived at either alone or in combination with existing treatments.

'"/>




Related medicine news :

1. Virus Level could Predict Cervical Cancer Risk
2. Smallpox Vaccine May Help Fight Cervical Cancer
3. Obesity Increases Risk of Cervical Cancer
4. Reducing The Risk Of Cervical Cancer
5. Improving Fertility In Patients With Cervical Cancer
6. Vaccine for Cervical cancer
7. Cervical spinal injury patients may have more damage left undetected
8. Cervical Cancer Vaccine To Be Developed In India
9. Cervical Cancer Recurrence Risk Even After Removal Of Pre-Cancerous Cells
10. HPV Vaccines for Cervical Cancer
11. Vaccine For Cervical Cancer Awaits Approval
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/30/2016)... , ... April 30, 2016 , ... Orlando-based Maximized Living ... they go for gold in Rio. Under the care of Maximized Living doctors ... , In an unprecedented showing, Maximized Living is sending the largest contingent of elite ...
(Date:4/29/2016)... ... April 30, 2016 , ... Mercy College is expanding its Graduate Business ... will be expanding due to high demand: Master of Business Administration (MBA), Master of ... summer. , School of Business Graduate Program Chair Dr. Ray Manganelli said: ...
(Date:4/29/2016)... ... 29, 2016 , ... Since launching its annual volunteer campaign ... the footwear industry, has broken all previous participation records in its first two ... states during the months of April and May, the 2016 Footwear Cares initiative ...
(Date:4/29/2016)... Sedona, Arizona (PRWEB) , ... April 29, 2016 ... ... Shamanic Healing and Spiritual Awakening , announces the addition Onnit brand Alpha BRAIN ... , The addition of Onnit brain and mood optimization products to the store ...
(Date:4/29/2016)... , ... April 29, 2016 , ... On Tuesday, April ... across the Southeast, celebrated the signature of Gov. Nathan Deal on SB 258, the ... Duncan (R - Cumming), offers a 70% tax credit to individuals and corporations which ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... 2016 Tie-up with Government hospitals ... to save newborns   Fortis La Femme, ... in collaboration with Breast Milk Foundation (BMF), a non-profit organization ... Milk Bank, ,Amaara, in Delhi-NCR today. This non-profit centre recognizes ... infants and should be available to babies deprived of mother,s ...
(Date:4/27/2016)... 2016 Oasmia Pharmaceutical AB ... a new generation of drugs within human and ... for Paclical/Apealea in the Phase III study that ... ovarian cancer. These preliminary results showed non-inferiority between ... carboplatin versus Taxol in combination with carboplatin. In ...
(Date:4/26/2016)... Mich. , April 26, 2016 Diplomat ... promotion of Jennifer Hagerman , Pharm D., to ... her growing role at Diplomat, Hagerman will continue to ... the company that delivers custom education and training to ... the specialty pharmacy industry. Diplomat University also houses the ...
Breaking Medicine Technology: