Navigation Links
Cervical Cancer Can Now Be Better Handled With Gene Silencing Therapy

Queensland University researchers have ventured into a new approach called ‘gene silencing’ for the treatment of cervical cancer. The technique is targeted towards turning // the cancer causing genes on and off to help cervical cancer patients.

Certain genes called tumor suppressor genes are responsible for preventing the occurrence of a particular type of cancer. On the other hand, tumor-promoting genes help in the initiation and progression of tumor. A logical way to combat tumor is to either turn on the tumor suppressor genes or turn off the tumor promoting genes.

Cervical cancer is the leading cause of cancer death in women aged 25-50 worldwide. Infection with the human papilloma virus is regarded to be a causative factor in cervical cancer as it results in the over-production of two viral cancer-causing genes called E6 and E7.

The researchers were successful in killing the cervical cancer cells by turning of the production of these genes in cancer cells. Furthermore, gene silencing was found to enhance the effect of chemotherapy by up to four times.

One main advantage of this approach is that the normal cells remain unaffected during manipulation, as the main target is the viral gene. The researchers hope to exploit this form of treatment to all forms of cervical cancer including the premalignant lesions picked up by the pap smear and especially for advanced cervical cancers where the cancer has moved to other sites such as the lung or liver.

The current results have been demonstrated in cervical cancer cell lines grown in test tubes. The next step is to achieve the same desired effect in animal models. If successful, the next stage of research will focus on the development of materials for human trials to allow proper delivery of the drug to patients and to investigate whether other cancer types can be treated this way.

Although the trials are under an experimental phase, if successful, it can turn out to be an advanced form of the currently existing treatment options such as surgery, radiotherapy and chemotherapy. At the least, a cancer-specific treatment for advanced cervical cancers would be arrived at either alone or in combination with existing treatments.

'"/>




Related medicine news :

1. Virus Level could Predict Cervical Cancer Risk
2. Smallpox Vaccine May Help Fight Cervical Cancer
3. Obesity Increases Risk of Cervical Cancer
4. Reducing The Risk Of Cervical Cancer
5. Improving Fertility In Patients With Cervical Cancer
6. Vaccine for Cervical cancer
7. Cervical spinal injury patients may have more damage left undetected
8. Cervical Cancer Vaccine To Be Developed In India
9. Cervical Cancer Recurrence Risk Even After Removal Of Pre-Cancerous Cells
10. HPV Vaccines for Cervical Cancer
11. Vaccine For Cervical Cancer Awaits Approval
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... , ... October 13, 2017 , ... Ellevate Network, the ... business to advocate for action towards gender equality at their inaugural Summit in New ... the globe, and reached a social audience of over 3 million. To watch the ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, ... lowdown on sciatica in a new episode of "Success Files," which is an ... and innovation and investigates each subject in-depth with passion and integrity. , Sciatica ...
(Date:10/13/2017)... , ... October 13, 2017 , ... “America On The ... identity. “America On The Brink” is the creation of published author, William Nowers. ... great-grandchildren. As a WWII veteran, he spent thirty years in the Navy. ...
(Date:10/12/2017)... ... ... Planet Fitness, one of the largest and fastest growing franchisors and operators ... location in Covington, LA at 401 N. U.S. Highway 190, in January of 2018. ... in the Holiday Square shopping center. Its location allows it to serve both Covington ...
(Date:10/12/2017)... ... 2017 , ... The American College of Medical Informatics (ACMI) will present the ... Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium ... a pioneer in the field of medical informatics, this prestigious award is presented to ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... 2, 2017  AllianceRx Walgreens Prime, the combined central ... and pharmacy benefit manager Prime Therapeutics LLC (Prime), today ... included the unveiling of new signage at its headquarters ... as at a few other company-owned facilities across the ... patients, some of whom will begin to see the ...
(Date:9/28/2017)... Hill-Rom Holdings, Inc. (NYSE: HRC), will host ... webcast on Friday, November 3, 2017, beginning at 7:00 ... approximately 8:30 a.m. (CDT) / 9:30 a.m. (EDT). ... performance and guidance for 2018, Hill-Rom executives will also ... performance, and long-range financial outlook through 2020. ...
(Date:9/27/2017)... , Sept. 27, 2017  DarioHealth Corp. (NASDAQ: DRIO), a leading global ... that its MyDario product is expected to appear on The Dr. Oz ... Dr. Oz Show airs in your area: http://www.doctoroz.com/page/where-watch-dr-oz-show ... The nine-time Emmy award-winning, The Dr. Oz Show kicked ... The segment features ...
Breaking Medicine Technology: